Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Patrick Kearney"'
Autor:
Tiantian Cui, Sergio Corrales-Guerrero, Veronica Castro-Aceituno, Sindhu Nair, Daniel C. Maneval, Curtis Monnig, Patrick Kearney, Sam Ellis, Nicholas Raheja, Neil Raheja, Terence M. Williams
Publikováno v:
Molecular Therapy: Oncolytics, Vol 30, Iss , Pp 181-192 (2023)
Albumin is an attractive candidate carrier for the development of novel therapeutic drugs. Gemcitabine has been FDA approved for the treatment of solid tumors; however, new drugs that optimize gemcitabine delivery are not available for clinical use.
Externí odkaz:
https://doaj.org/article/082c3e3a95e54afc8d405e1d14c0a9ab
Autor:
Brenda Roxana García-Rivera, Efraín Antonio Rodríguez-Urrutia, Ada Yanira Arias-de Linares, Marcia Lizeth Barrera-de-Calder´ón, Sean Patrick Kearney
Publikováno v:
Revista Minerva. 3:60-73
La investigación se realizó de mayo a noviembre 2015 en los siguientes sitios: municipios de “Las Vueltas”, “La Laguna” y “Chalatenango”, cantones “Guarjila” y “Upatoro”, y en la región de la Mancomunidad La Montañona, departa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b90a54aa9711e03ce805ed08a3a5c66e
https://doi.org/10.5377/revminerva.v3i2.12559
https://doi.org/10.5377/revminerva.v3i2.12559
Autor:
Patrick Kearney, Yuanxi Zhang, Yanglan Tan, Elizabeth Kahuno, Tucker Conklin, Rita Fagan, Rebecca Pavchinskiy, Scott Shaffer, Zhenyu Yue, Haley Melikian
Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease and arises from dopamine (DA) neuron death selectively in the substantia nigra pars compacta (SNc) . Rit2 is a reported PD risk allele, and recent single cell transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b14e8612587972100fa03b79f569a4a9
https://doi.org/10.21203/rs.3.rs-2944614/v1
https://doi.org/10.21203/rs.3.rs-2944614/v1
Autor:
Tiantian Cui, Sergio Corrales-Guerrero, Dan Maneval, Curtis Monnig, Patrick Kearney, Sam Ellis, Terence M. Williams
Publikováno v:
Cancer Research. 82:4070-4070
Purpose: Human serum albumin (HSA) is an attractive candidate as a carrier in developing novel albumin-bound nanoparticle therapeutic drugs. Gemcitabine has been used in the treatment of solid tumors, including non-small cell lung, pancreatic, bladde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b714e6743e90696f8cd75044d58f48f7
https://doi.org/10.1158/1538-7445.am2022-4070
https://doi.org/10.1158/1538-7445.am2022-4070
Autor:
Yoon-Suk Hwang, Patrick Kearney
Publikováno v:
Mindfulness in Behavioral Health ISBN: 9783319765372
The theory and practice of mindfulness originate in an ancient oriental religion and yet is being appropriated by modern social and psychological sciences. This has created problems in how mindfulness and its theoretical framework can be adapted to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b6308de1e5ecc017be5cc2abad4591
https://doi.org/10.1007/978-3-319-76538-9_15
https://doi.org/10.1007/978-3-319-76538-9_15
Autor:
Patrick Kearney, Yoon-Suk Hwang
Publikováno v:
Research in Developmental Disabilities. 34:314-326
Can individuals with developmental disabilities learn mindfulness? If so, with what result? A systematic literature review identified 12 studies that taught mindfulness practice to individuals with mild to severe developmental disabilities, demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6439f029faf1f84fdb5b51a80e7d45e
https://doi.org/10.1016/j.ridd.2012.08.008
https://doi.org/10.1016/j.ridd.2012.08.008
Autor:
Patrick Kearney, Yoon-Suk Hwang
Publikováno v:
Journal of Child and Family Studies. 23:497-509
Parental and professional caregivers of individuals with developmental disabilities (DD) often experience stress and hardship associated with their role, placing them in real danger of burnout and affecting their quality of care. Mindfulness practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b161170dc07f1e37d4e6ac996f4e5cb
https://doi.org/10.1007/s10826-012-9707-9
https://doi.org/10.1007/s10826-012-9707-9
Autor:
Yoon-Suk Hwang, Patrick Kearney
This book presents emerging research on the effectiveness of mindfulness methods in reducing behavior problems associated with autism spectrum disorders (ASD) in children. The volume synthesizes current research and theories on the therapeutic uses o
Autor:
John M. Nuss, Gordon Mark Stott, Hongwang Du, E.S. Koltun, A.D Laird, I Ngan, Amy Lew Tsuhako, Adam A. Galan, Ping Huang, Thomas J. Stout, Patrick Kearney, Chan, Stuart Johnston, W. Zhang, R Lin, Stefan Engst, Peiwen Zhou, L Mock, Maurizio Franzini, Brown S David, Moon Hwan Kim, Brian Kane, Naing Aay, Arlyn Arcalas, Wei Xu, Michael Pack, Peiwen Yu, Cristiana A. Zaharia
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:3732-3738
A series of substituted benzofuropyrimidinones with pan-PIM activities and excellent selectivity against a panel of diverse kinases is described. Initial exploration identified aryl benzofuropyrimidinones that were potent, but had cell permeability l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ad4fc4a63c7985616e1d826de93fb2
https://doi.org/10.1016/j.bmcl.2012.04.025
https://doi.org/10.1016/j.bmcl.2012.04.025
Autor:
Arlyn Arcalas, Richards Steven J, Amy Lew Tsuhako, Naing Aay, Kim Ferguson, Arthur Plonowski, Gordon Mark Stott, Wei Xu, Jenny Young, Peiwen Yu, Wentao Zhang, Charles R. Holst, Kevin Noson, Cristiana A. Zaharia, Brown S David, Hongwang Du, Manisha Mohan, Ping Huang, Thomas J. Stout, Adam A. Galan, Patrick Kearney, David W. Markby, Stefan Engst, Maurizio Franzini, Peiwen Zhou, John M. Nuss, Brian Kane, Kenneth J. Shaw, Elena S. Koltun, Scott Robertson, Moon Hwan Kim, Vicky Chan, Jia Li
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:3727-3731
CDC7 is a serine/threonine kinase that has been shown to be required for the initiation and maintenance of DNA replication. Up-regulation of CDC7 is detected in multiple tumor cell lines, with inhibition of CDC7 resulting in cell cycle arrest. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728a0209cfabeafbb8605b83873ecf26
https://doi.org/10.1016/j.bmcl.2012.04.024
https://doi.org/10.1016/j.bmcl.2012.04.024