Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Patrick K, Randall"'
Autor:
Konstantin Voronin, Patricia K. Latham, Michaela Hoffman, Joseph P. Schacht, Sarah W. Book, Raymond F. Anton, Patrick K. Randall, Willam Bailey Glen
Publikováno v:
Alcohol Clin Exp Res
Background While the opiate antagonist, naltrexone, is approved for treating alcohol use disorder (AUD), not everyone who receives the medication benefits from it. This study evaluated whether the OPRM1 SNP rs1799971 interacts with the dopamine trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd8d735c20b8ec785f04ca8b775c175
https://pubmed.ncbi.nlm.nih.gov/32772383
https://pubmed.ncbi.nlm.nih.gov/32772383
Autor:
Raymond F. Anton, Michaela Hoffman, Joseph P. Schacht, Patrick K. Randall, Patricia K. Latham, Sarah W. Book, Konstantin Voronin
Publikováno v:
Alcoholism: Clinical and Experimental Research. 42:751-760
BACKGROUND The opioid antagonist naltrexone is not efficacious for every alcohol treatment seeker. However, various individual factors, such as genetic differences and nicotine-use/smoking status, have been suggested as predictors of naltrexone respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97810ce3aa95d74ebcf98dbc46b7a29
https://doi.org/10.1111/acer.13601
https://doi.org/10.1111/acer.13601
Publikováno v:
Neuropsychopharmacology. 43:1247-1256
Dopamine (DA) signaling regulates many aspects of Alcohol Use Disorder (AUD). However, clinical studies of dopaminergic medications, including the DA partial agonist aripiprazole (APZ), have been inconsistent, suggesting the possibility of a pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3590f5d9fb8b9e499db83d1f545cb395
https://doi.org/10.1038/npp.2017.298
https://doi.org/10.1038/npp.2017.298
Publikováno v:
Alcoholism: Clinical and Experimental Research. 41:1370-1380
Background Aspects of impulsivity have been implicated in the development, or maintenance, of Alcohol Use Disorder (AUD). The brain dopamine system is implicated in both reward processing/memory (typically subcortical) and in brain inhibitory control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23484998e2243cd3f76b357ef0b43ec2
https://doi.org/10.1111/acer.13417
https://doi.org/10.1111/acer.13417
Autor:
Raymond F. Anton, Patricia K. Latham, Sarah W. Book, Patrick K. Randall, Joseph P. Schacht, Konstantin Voronin, Hugh Myrick
Publikováno v:
Neuropsychopharmacology. 42:2640-2653
Naltrexone reduces drinking among individuals with alcohol use disorders (AUDs), but it is not effective for everyone. Variability in its effects on reward-related brain activation, genetic variation, and/or cigarette smoking may account for this mix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e20e609eecd3f90fbf7c1baaee8e10b
https://doi.org/10.1038/npp.2017.74
https://doi.org/10.1038/npp.2017.74
Autor:
Robert W. Williams, L. Judson Chandler, Jennifer A. Rinker, Heather Trantham-Davidson, Maren L. Smith, Michael F. Miles, Patrick K. Randall, Howard C. Becker, Diana Fulmer, Marcelo F. Lopez, Patrick J. Mulholland
Publikováno v:
Alcohol. 58:33-45
Alcohol (ethanol) dependence is a chronic relapsing brain disorder partially influenced by genetics and characterized by an inability to regulate harmful levels of drinking. Emerging evidence has linked genes that encode KV7, KIR, and KCa2 K+ channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc48c1db90fa2d71dc3a329d37959d5
https://doi.org/10.1016/j.alcohol.2016.05.007
https://doi.org/10.1016/j.alcohol.2016.05.007
Publikováno v:
Journal of Studies on Alcohol and Drugs. 77:354-361
People consume alcohol at problematic levels for many reasons. These different motivational pathways may have different biological underpinnings. Valid, brief measures that discriminate individuals' reasons for drinking could facilitate inquiry into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8670e84137fe2351695f7c70c62f28ec
https://doi.org/10.15288/jsad.2016.77.354
https://doi.org/10.15288/jsad.2016.77.354
Autor:
Patrick K. Randall, Byron A. Campbell
Publikováno v:
Aberrant Development in Infancy ISBN: 9781351169042
Aberrant Development in Infancy
Aberrant Development in Infancy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9ff0831548b4cfe875ef6f92ad65cf7
https://doi.org/10.4324/9781351169042-7
https://doi.org/10.4324/9781351169042-7
Autor:
Rachel J. Smith, Benjamin A. Hughes, John J. Woodward, Patrick K. Randall, Peter W. Kalivas, Jacob T. Beckley
Publikováno v:
Addiction Biology. 21:530-546
Abused inhalants are voluntarily inhaled at high concentrations to produce intoxicating effects. Results from animal studies show that the abused inhalant toluene triggers behaviors, such as self-administration and conditioned place preference, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c46f87af438acfc8f48455df05404f9
https://doi.org/10.1111/adb.12235
https://doi.org/10.1111/adb.12235
Autor:
Marcelo F. Lopez, Heather Trantham-Davidson, Stan B. Floresco, Justin T. McGonigal, Richard Yaxley, Justin T. Gass, Patrick K. Randall, L. Judson Chandler, William B. Glen
Publikováno v:
Neuropsychopharmacology. 39:2570-2583
The prefrontal cortex (PFC) is a brain region that is critically involved in cognitive function and inhibitory control of behavior, and adolescence represents an important period of continued PFC development that parallels the maturation of these fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776096b618347ac52e30c6fe2cff831f
https://doi.org/10.1038/npp.2014.109
https://doi.org/10.1038/npp.2014.109