Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Patrick Jack, Spencer"'
Autor:
Rodolfo Ferreira Marques, Wagner Quintilio, Marcos Camargo Knirsch, Tamara Mieco Fucase, Patrick Jack Spencer, Marco Antonio Stephano
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022)
Abstract The treatment with hyperimmune sera constitute the only specific and effective therapy available against snakebite envenomation, most common in developing countries. Serum quality is an important factor on patient recovery time and in the in
Externí odkaz:
https://doaj.org/article/ed7ecd1754b146258e29b75fada10165
Autor:
Felipe Raimondi Guidolin, Kemily Stephanie de Godoi, Angela Alice Amadeu Megale, Cristiane Castilho Fernandes da Silva, Roberto Tadashi Kodama, Daniela Cajado-Carvalho, Leo Kei Iwai, Patrick Jack Spencer, Fernanda Calheta Vieira Portaro, Wilmar Dias da Silva
Publikováno v:
Toxins, Vol 15, Iss 9, p 584 (2023)
Accidents with snakes are responsible for about 32,000 deaths annually in sub-Saharan Africa, caused mostly by snakes from the genus Bitis, in particular Bitis arietans. B. arietans venom is composed of a complex mixture of toxins, mainly metalloprot
Externí odkaz:
https://doaj.org/article/0e60d8ffdb78430f90d2ff59203e729d
Autor:
Kemily Stephanie de Godoi, Felipe Raimondi Guidolin, Fernanda Calheta Vieira Portaro, Patrick Jack Spencer, Wilmar Dias da Silva
Publikováno v:
Toxins, Vol 15, Iss 4, p 264 (2023)
Bitis arietans is a medically important snake found in Sub-Saharan Africa. The envenomation is characterized by local and systemic effects, and the lack of antivenoms aggravates the treatment. This study aimed to identify venom toxins and develop ant
Externí odkaz:
https://doaj.org/article/79a087c8001e4116b6ed9655e388f7ef
Autor:
Wilmar Dias da Silva, Sonia A. De Andrade, Ângela Alice Amadeu Megale, Daniel Alexandre De Souza, Osvaldo Augusto Sant’Anna, Fábio Carlos Magnoli, Felipe Raimondi Guidolin, Kemily Stephanie Godoi, Lucas Yuri Saladini, Patrick Jack Spencer, Fernanda Calheta Vieira Portaro
Publikováno v:
Toxins, Vol 14, Iss 9, p 606 (2022)
Snakebite envenomation is considered a neglected tropical disease, affecting tens of thousands of people each year. The recommended treatment is the use of antivenom, which is composed of immunoglobulins or immunoglobulin fragments obtained from the
Externí odkaz:
https://doaj.org/article/605280e763be432dbf575c5f3d970262
Autor:
Giselle Pacifico Sartori, Andréa da Costa, Fernanda Lúcio dos Santos Macarini, Douglas Oscar Ceolin Mariano, Daniel Carvalho Pimenta, Patrick Jack Spencer, Luiz Henrique da Silva Nali, Andrés Jimenez Galisteo Jr.
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 27 (2021)
Abstract Background Tetanus toxin blocks the release of the inhibitory neurotransmitters in the central nervous system and causes tetanus and its main form of prevention is through vaccination. The vaccine is produced by inactivation of tetanus toxin
Externí odkaz:
https://doaj.org/article/0080d5c38a93493897adfdadb347f0a5
Autor:
Carla Daruich de Souza, Angelica Bueno Barbezan, Wilmmer Alexander Arcos Rosero, Sofia Nascimento dos Santos, Diego Vergaças de Sousa Carvalho, Carlos Alberto Zeituni, Emerson Soares Bernardes, Daniel Perez Vieira, Patrick Jack Spencer, Martha Simões Ribeiro, Maria Elisa Chuery Martins Rostelato
Publikováno v:
Nanomaterials, Vol 12, Iss 2, p 187 (2022)
New forms of cancer treatment, which are effective, have simple manufacturing processes, and easily transportable, are of the utmost necessity. In this work, a methodology for the synthesis of radioactive Gold-198 nanoparticles without the use of sur
Externí odkaz:
https://doaj.org/article/8c0419ce9465414a8cb14bade277a833
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 21, Iss 0 (2015)
AbstractBackground:Since ionizing radiation has the potential to alter the molecular structure and affect the biologica properties of biomolecules, it has been successfully employed to attenuate animal toxins. The present study aimed to characterize
Externí odkaz:
https://doaj.org/article/c92457a2d20347b8a36738865e66ad26
Autor:
Juliana Mozer Sciani, Fernanda Cortinhas Barbosa, Sandra Coccuzzo Sampaio, Fernanda D'Amélio, Guilherme Rabelo Coelho, Daniel C. Pimenta, Patricia Brigatte, Rafael Silva Santos, Pedro Prezotto Neto, Patrick Jack Spencer
Publikováno v:
Fish & Shellfish Immunology. 93:832-840
Stingrays skin secretions are largely studied due to the human envenoming medical relevance of the sting puncture that evolves to inflammatory events, including necrosis. Such toxic effects can be correlated to the biochemical composition of the stin
Autor:
Ruth Camargo Vassão, Juliana Mozer Sciani, Adriana da Costa Neves, Carlos Jared, Patrick Jack Spencer, Daniel C. Pimenta, Marta M. Antoniazzi
Publikováno v:
The Protein Journal. 38:83-94
Amphibians are, currently, considered the first vertebrates that had performed the aquatic to terrestrial transition during evolution; therefore, water balance and dehydration control were prerequisites for such environment conquering. Among anurans,
Publikováno v:
Brazilian Journal of Development. 5:24780-24793
O objetivo principal deste artigo e caracterizar o Perfil Clinico e Epidemiologico da Leishmaniose Tegumentar Americana, no periodo de 2010 a 2016, do Hospital de Doencas Tropicais (HDT) da Universidade Federal do Tocantins no municipio de Araguaina-