Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Patrick J. Skelly"'
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Schistosomiasis is a parasitic disease caused by trematodes of the genus Schistosoma. The intravascular worms acquire the nutrients necessary for their survival from host blood. Since all animals are auxotrophic for riboflavin (vi
Externí odkaz:
https://doaj.org/article/e317cf90d47b4fb0a04b7edd9fb6f283
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28271- (2024)
Schistosomes are intravascular parasitic worms infecting >200 million people globally. Here we examine how the worms acquire an essential nutrient - vitamin B2 (riboflavin). We demonstrate that all intravascular life stages (schistosomula, adult male
Externí odkaz:
https://doaj.org/article/35428c9b62ce4f85a3db1ef102dfa05a
Autor:
Patrick J. Skelly, Akram A. Da’dara
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Schistosomes are long-lived parasitic worms that infect >200 million people globally. The intravascular life stages are known to display acetylcholinesterase (AChE) activity internally as well as, somewhat surprisingly, on external tegumental membran
Externí odkaz:
https://doaj.org/article/c8f1ef2a98b64216a191681618ac716a
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 568-579 (2020)
Infection with intravascular platyhelminths of the genus Schistosoma can result in the debilitating disease schistosomiasis. Schistosomes (blood flukes) can survive in the host for many years. We hypothesize that proteins on their host-interactive su
Externí odkaz:
https://doaj.org/article/4783348f8ee441e7ada5d28a2f1dea9c
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Fructose 1,6-bisphosphate aldolase is a ubiquitous cytosolic enzyme that catalyzes the fourth step of glycolysis. Aldolases are classified into three groups: Class-I, Class-IA, and Class-II; all classes share similar structural features but low amino
Externí odkaz:
https://doaj.org/article/c82f883841ad4da58ec921860ea73b77
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Schistosomes are parasitic platyhelminths that currently infect >200 million people globally. The adult worms can live within the vasculature of their hosts for many years where they acquire all nutrients necessary for their survival and growth. In t
Externí odkaz:
https://doaj.org/article/4645d7baa1964c10acba6394b0f2c9fd
Publikováno v:
Pathogens, Vol 11, Iss 2, p 155 (2022)
Schistosomes (blood flukes) can survive in the bloodstream of their hosts for many years. We hypothesize that proteins on their host-interactive surface impinge on host biochemistry to help ensure their long-term survival. Here, we focus on a surface
Externí odkaz:
https://doaj.org/article/a323eeeef42d42c9a98552a4ce26b3d4
Publikováno v:
Biology Open, Vol 9, Iss 3 (2020)
Schistosomes are intravascular blood flukes that cause the parasitic disease schistosomiasis. In agreement with Schistosoma mansoni (Sm) proteomic analysis, we show here that the normally intracellular glycolytic enzyme glyceraldehyde-3-phosphate deh
Externí odkaz:
https://doaj.org/article/f775ac38370a4c46bae407cb33c068d0
Publikováno v:
Parasites & Vectors, Vol 11, Iss 1, Pp 1-10 (2018)
Abstract Background Schistosomes are blood dwelling parasitic worms that cause the debilitating disease schistosomiasis. Here we examined the influence of the parasites on their external environment by monitoring the impact of adult Schistosoma manso
Externí odkaz:
https://doaj.org/article/932a70840c344b268072ad6d90462310
Autor:
Andrea Angeli, Mariana Pinteala, Stelian S. Maier, Bogdan C. Simionescu, Akram A. Da’dara, Patrick J. Skelly, Claudiu T. Supuran
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1842 (2020)
Schistosomiasis is a debilitating infection provoked by parasitic flatworms called schistosomes. The species Schistosoma mansoni is endemic in Africa, where it causes intestinal schistosomiasis. Recently, an α-carbonic anhydrase (CA, EC 4.2.1.1) was
Externí odkaz:
https://doaj.org/article/e1ba47ed44974de0947fa405109a0683