Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Patrick J. McMillen"'
Autor:
Timothy M. Willson, Joe Watson, John T. Moore, Patrick J. McMillen, Bryan Goodwin, Jodi M. Maglich
Publikováno v:
Journal of Biological Chemistry. 279:19832-19838
The orphan nuclear receptor CAR (NR1I3) has been characterized as a central component in the coordinate response to xenobiotic and endobiotic stress. In this study, we demonstrate that CAR plays a pivotal function in energy homeostasis and establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c8af0f950d0b88486f20194a4c9bae
https://doi.org/10.1074/jbc.m313601200
https://doi.org/10.1074/jbc.m313601200
Autor:
Elizabeth Docherty, Patrick J. McMillen, Laura E. Parton, Yingnian Shen, Frédérique Diraison, Celia P. Briscoe, Erin Sharpe, Guy A. Rutter
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 291(5)
Accumulation of intracellular lipid may contribute to defective insulin secretion in type 2 diabetes. Although Zucker diabetic fatty (ZDF; fa/fa) rat islets are fat-laden and overexpress the lipogenic master gene, sterol regulatory element binding pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a41f9b9651bc06b7275d3d85342ff11
https://pubmed.ncbi.nlm.nih.gov/16772326
https://pubmed.ncbi.nlm.nih.gov/16772326
Autor:
Patrick J. McMillen, Callum J. Bell, Nancy S. Shepherd, Linda P. Briley, Eric H. Lai, Jan Kopf, David Briley, Daniel K. Burns, Geoff Joslyn, Kirby Gottschalk, James L. Weber, Melanie Reisman, Maha Chabhar Karnoub, David Vaske, Donald C. Holt, Hakan Sakul, Quan Nguyen, Michael J. Wagner, Margaret G. Ehm
Publikováno v:
American journal of human genetics. 66(6)
Type 2 diabetes is a serious, genetically influenced disease for which no fully effective treatments are available. Identification of biochemical or regulatory pathways involved in the disease syndrome could lead to innovative therapeutic interventio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc40e28d8448a008076e45ace85df23
https://pubmed.ncbi.nlm.nih.gov/10793009
https://pubmed.ncbi.nlm.nih.gov/10793009
Publikováno v:
Toxicology and applied pharmacology. 143(1)
Certain human heritable forms of colon cancer have characteristically high frequencies of microsatellite alterations. These microsatellite changes are markers of genomic instability and the direct consequence of mutations in genes involved with DNA m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b3685e2b3395e9368832856213af42
https://pubmed.ncbi.nlm.nih.gov/9073604
https://pubmed.ncbi.nlm.nih.gov/9073604