Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Patrick J. LeRoy"'
Autor:
Todd B. Sells, Christopher F. Claiborne, Joseph B. Bolen, Melissa S. Germanos, Matthew D. Silva, Rachel E. Gershman, Patrick J. LeRoy, Marc L. Hyer, David A. Janowick, Deborah R. Wysong, Jessica J. Huck, Vaishali Shinde, Wei Chen, Stephen G. Stroud, Kara M. Hoar, Mengkun Zhang, Lee Silverman, Arijit Chakravarty, Jeffrey A. Ecsedy, Mark G. Manfredi
PDF file - 34K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd0a58f7cbd736328e57e7a23f7e5ec
https://doi.org/10.1158/1078-0432.22446309.v1
https://doi.org/10.1158/1078-0432.22446309.v1
Autor:
Todd B. Sells, Christopher F. Claiborne, Joseph B. Bolen, Melissa S. Germanos, Matthew D. Silva, Rachel E. Gershman, Patrick J. LeRoy, Marc L. Hyer, David A. Janowick, Deborah R. Wysong, Jessica J. Huck, Vaishali Shinde, Wei Chen, Stephen G. Stroud, Kara M. Hoar, Mengkun Zhang, Lee Silverman, Arijit Chakravarty, Jeffrey A. Ecsedy, Mark G. Manfredi
Purpose: Small-molecule inhibitors of Aurora A (AAK) and B (ABK) kinases, which play important roles in mitosis, are currently being pursued in oncology clinical trials. We developed three novel assays to quantitatively measure biomarkers of AAK inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2b8c17037133a1bc1c17abc8089fa3
https://doi.org/10.1158/1078-0432.c.6520713
https://doi.org/10.1158/1078-0432.c.6520713
Autor:
Todd B. Sells, Christopher F. Claiborne, Joseph B. Bolen, Melissa S. Germanos, Matthew D. Silva, Rachel E. Gershman, Patrick J. LeRoy, Marc L. Hyer, David A. Janowick, Deborah R. Wysong, Jessica J. Huck, Vaishali Shinde, Wei Chen, Stephen G. Stroud, Kara M. Hoar, Mengkun Zhang, Lee Silverman, Arijit Chakravarty, Jeffrey A. Ecsedy, Mark G. Manfredi
PDF file - 27K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889d43f96b1d811fca5e3c164e018a19
https://doi.org/10.1158/1078-0432.22446306
https://doi.org/10.1158/1078-0432.22446306
Autor:
Todd B. Sells, Christopher F. Claiborne, Joseph B. Bolen, Melissa S. Germanos, Matthew D. Silva, Rachel E. Gershman, Patrick J. LeRoy, Marc L. Hyer, David A. Janowick, Deborah R. Wysong, Jessica J. Huck, Vaishali Shinde, Wei Chen, Stephen G. Stroud, Kara M. Hoar, Mengkun Zhang, Lee Silverman, Arijit Chakravarty, Jeffrey A. Ecsedy, Mark G. Manfredi
PDF file - 65K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9737acec25fe2137ea4f1aa5f53a36c5
https://doi.org/10.1158/1078-0432.22446312.v1
https://doi.org/10.1158/1078-0432.22446312.v1
Autor:
Todd B. Sells, Christopher F. Claiborne, Joseph B. Bolen, Melissa S. Germanos, Matthew D. Silva, Rachel E. Gershman, Patrick J. LeRoy, Marc L. Hyer, David A. Janowick, Deborah R. Wysong, Jessica J. Huck, Vaishali Shinde, Wei Chen, Stephen G. Stroud, Kara M. Hoar, Mengkun Zhang, Lee Silverman, Arijit Chakravarty, Jeffrey A. Ecsedy, Mark G. Manfredi
PDF file - 36K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fa6e54e4641152cddff0837b8a5697
https://doi.org/10.1158/1078-0432.22446315
https://doi.org/10.1158/1078-0432.22446315
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Figures 5-7 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5550a69979710e76b33bf0c32049758a
https://doi.org/10.1158/0008-5472.22383065
https://doi.org/10.1158/0008-5472.22383065
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Figure 8 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1f22fa15aad5f236df43c06c726794
https://doi.org/10.1158/0008-5472.22383071
https://doi.org/10.1158/0008-5472.22383071
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Methods, Figure and Table Legends from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0800f85e6a3c750e356d1153687ea4d6
https://doi.org/10.1158/0008-5472.22383062.v1
https://doi.org/10.1158/0008-5472.22383062.v1
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Multiple pathways have been proposed to explain how proteasome inhibition induces cell death, but mechanisms remain unclear. To approach this issue, we performed a genome-wide siRNA screen to evaluate the genetic determinants that confer sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::447f83f4a5ac4ed58b1abc343d56192c
https://doi.org/10.1158/0008-5472.c.6500411
https://doi.org/10.1158/0008-5472.c.6500411
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Figures 1-4 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176e6d9a80ab572faac33eb8592ee188
https://doi.org/10.1158/0008-5472.22383068.v1
https://doi.org/10.1158/0008-5472.22383068.v1