Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Patrick J. Ferrara"'
Autor:
Justin L. Shahtout, Hiroaki Eshima, Patrick J. Ferrara, J. Alan Maschek, James E. Cox, Micah J. Drummond, Katsuhiko Funai
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 1, Pp 319-330 (2024)
Abstract Background Lipid hydroperoxides (LOOH) have been implicated in skeletal muscle atrophy with age and disuse. Lysophosphatidylcholine acyltransferase 3 (LPCAT3), an enzyme of the Lands cycle, conjugates a polyunsaturated fatty acyl chain to a
Externí odkaz:
https://doaj.org/article/7c0fa7d511e2444a85949c4cde575b28
Autor:
Elena M. Yee, Carson T. Hauser, Jonathan J. Petrocelli, Naomi M. M. P. de Hart, Patrick J. Ferrara, Princess Bombyck, Zachary J. Fennel, Lisha van Onselen, Sohom Mookerjee, Katsuhiko Funai, J. David Symons, Micah J. Drummond
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: A hallmark of aging is poor muscle recovery following disuse atrophy. Efficacious strategies to enhance muscle recovery following disuse atrophy in aging are non-existent. Prior exercise training could result in favorable muscle morphol
Externí odkaz:
https://doaj.org/article/f3ceec9fe95142e98734ae6ea2f14d58
Autor:
Jordan M. Johnson, Anthony R.P. Verkerke, J. Alan Maschek, Patrick J. Ferrara, Chien-Te Lin, Kimberly A. Kew, P. Darrell Neufer, Irfan J. Lodhi, James E. Cox, Katsuhiko Funai
Publikováno v:
Molecular Metabolism, Vol 31, Iss , Pp 55-66 (2020)
Objective: Phosphatidylethanolamine methyltransferase (PEMT) generates phosphatidylcholine (PC), the most abundant phospholipid in the mitochondria and an important acyl chain donor for cardiolipin (CL) biosynthesis. Mice lacking PEMT (PEMTKO) are co
Externí odkaz:
https://doaj.org/article/18dd0661e3eb419f9648dcc98c3e8fc2
Autor:
Patrick J. Ferrara, Paul T. Reidy, Jonathan J. Petrocelli, Elena M. Yee, Dennis K. Fix, Ziad S. Mahmassani, Jessie A. Montgomery, Alec I. McKenzie, Naomi M. M. P. de Hart, Micah J. Drummond
Publikováno v:
Journal of Applied Physiology. 134:923-932
We provide evidence that the whole body loss of CCL2 in mice has adverse impacts on whole body function and skeletal muscle-specific contractile characteristics and collagen content. These defects in muscle function worsened during the recovery from
Autor:
Jonathan J. Petrocelli, Naomi M.M.P. de Hart, Marisa J. Lang, Elena M. Yee, Patrick J. Ferrara, Dennis K. Fix, Amandine Chaix, Katsuhiko Funai, Micah J. Drummond
Publikováno v:
Aging. 15:1808-1832
Autor:
Patrick J Ferrara, Marisa J Lang, Jordan M Johnson, Shinya Watanabe, Kelsey L McLaughlin, John Alan Maschek, Anthony R P Verkerke, Piyarat Siripoksup, Amandine Chaix, James E Cox, Kelsey H Fisher-Wellman, Katsuhiko Funai
Publikováno v:
Life Metab
Weight loss from an overweight state is associated with a disproportionate decrease in whole-body energy expenditure that may contribute to the heightened risk for weight regain. Evidence suggests that this energetic mismatch originates from lean tis
Autor:
Justin L Shahtout, Hiroaki Eshima, Piyarat Siripoksup, MacKenzie J Pearson, Ziad S Mahmassani, Patrick J Ferrara, Alexis W Lyons, John Alan Maschek, Alek D Peterlin, Anthony RP Verkerke, Jordan M Johnson, Anahy Salcedo, Jonathan J Petrocelli, Edwin R Miranda, Ethan J Anderson, Sihem Boudina, Qitao Ran, James E Cox, Micah J Drummond, Katsuhiko Funai
Publikováno v:
eLife. 12
SummaryReactive oxygen species (ROS) accumulation is a cardinal feature of skeletal muscle atrophy. ROS refers to a collection of radical molecules whose cellular signals are vast, and it is unclear which downstream consequences of ROS are responsibl
Autor:
Justin L Shahtout, Hiroaki Eshima, Piyarat Siripoksup, MacKenzie J Pearson, Ziad S Mahmassani, Patrick J Ferrara, Alexis W Lyons, John Alan Maschek, Alek D Peterlin, Anthony RP Verkerke, Jordan M Johnson, Anahy Salcedo, Jonathan J Petrocelli, Edwin R Miranda, Ethan J Anderson, Sihem Boudina, Qitao Ran, James E Cox, Micah J Drummond, Katsuhiko Funai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e7eb61bb5551c675fd037ca1a17842
https://doi.org/10.7554/elife.85289.sa2
https://doi.org/10.7554/elife.85289.sa2
Autor:
Patrick J. Ferrara, Marisa J. Lang, Jordan M. Johnson, Shinya Watanabe, Kelsey L. McLaughlin, J. Alan Maschek, Anthony R.P. Verkerke, Piyarat Siripoksup, Amandine Chaix, James E. Cox, Kelsey H. Fisher-Wellman, Katsuhiko Funai
Weight loss is associated with a disproportionate decrease in whole-body energy expenditure that may contribute to the heightened risk for weight-regain. Evidence suggests that this energetic mismatch originates from lean tissue. Although this phenom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97aa369535ea4fb5a64c3fba983fc737
https://doi.org/10.1101/2022.12.21.521461
https://doi.org/10.1101/2022.12.21.521461
Autor:
Alec I. McKenzie, Ziad S. Mahmassani, Jonathan J. Petrocelli, Naomi M.M.P. de Hart, Dennis K. Fix, Patrick J. Ferrara, Paul C. LaStayo, Robin L. Marcus, Matthew T. Rondina, Scott A. Summers, Jordan M. Johnson, Joel D. Trinity, Katsuhiko Funai, Micah J. Drummond
Publikováno v:
Exp Gerontol
BACKGROUND AND AIMS. Metformin is the most commonly prescribed medication to treat diabetes. Emerging evidence suggests that metformin could have off target effects that might help promote healthy muscle aging, but these effects have not been thoroug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec3e81bb9a4e5c3884562c0cc58277f
https://europepmc.org/articles/PMC9237837/
https://europepmc.org/articles/PMC9237837/