Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Patrick J. Farmer"'
Autor:
Murugaeson R. Kumar, Patrick J. Farmer
Publikováno v:
Redox Biology, Vol 14, Iss , Pp 485-491 (2018)
Small oxoacids of sulfur (SOS) are elusive molecules like sulfenic acid, HSOH, and sulfinic acid, HS(O)OH, generated during the oxidation of hydrogen sulfide, H2S, in aqueous solution. Unlike their alkyl homologs, there is a little data on their gene
Externí odkaz:
https://doaj.org/article/8e717e01b7ee47d69224e75330469c07
Autor:
Ottis Scrivner, Ahmed Ismaeel, Murugaeson R. Kumar, Kristina Sorokolet, Panagiotis Koutakis, Patrick J. Farmer
Publikováno v:
Molecules, Vol 26, Iss 23, p 7160 (2021)
Hydrogen sulfide (H2S) is an endogenous signaling molecule which is important for cardiovascular health, but its mechanism of action remains poorly understood. Here, we report measurements of H2S as well as its oxidized metabolites, termed small oxoa
Externí odkaz:
https://doaj.org/article/119eb90b657c4c8994a550bdf5610770
Autor:
Ottis Scrivner, Kristina Sorokolet, Bessie W. Kebaara, Murugaeson R. Kumar, Patrick J. Farmer, Angelo Wong
Publikováno v:
ACS Chemical Biology. 16:1413-1424
This report characterizes and quantifies endogenous hydrogen sulfide (H2S) and small oxoacids of sulfur (SOS = HOSH, HOSOH) in a panel of cell lines including human cancer (A375 melanoma cells, HeLa cervical cells) and noncancer (HEK293 embryonic kid
Autor:
Ottis Scrivner, Long Dao, M Karen Newell-Rogers, Babbak Shahandeh, Frank L Meyskens, Susan Kurumi Kozawa, Feng Liu-Smith, Germán Plascencia-Villa, Miguel José-Yacamán, Shang Jia, Christopher J Chang, Patrick J Farmer
Publikováno v:
Metallomics
Metallomics : integrated biometal science, vol 14, iss 1
Metallomics : integrated biometal science, vol 14, iss 1
In this report, we investigate the toxicity of the ionophore thiomaltol (Htma) and Cu salts to melanoma. Divalent metal complexes of thiomaltol display toxicity against A375 melanoma cell culture resulting in a distinct apoptotic response at submicro
Autor:
Alton Hassell, Touradj Solouki, Patrick J. Farmer, Ian G.M. Anthony, Matthew R. Brantley, Michael T. Spiegel
Publikováno v:
Energy & Fuels. 32:10549-10555
Comprehensive characterization and structural elucidation of specific chemical subclasses within a complex mixture often require analyte separation, a variety of spectroscopic techniques, and inqui...
Autor:
Murugaeson R. Kumar, Patrick J. Farmer
Publikováno v:
Molecules
The authors wish to make the following corrections to this paper [...]
Autor:
Touradj Solouki, Patrick J. Farmer, Tara Clover, Murugaeson R. Kumar, Abayomi D. Olaitan, Christopher Becker
Publikováno v:
Nitric Oxide. 77:96-105
Several recent reports suggest that HNO may be produced endogenously by reaction of H2S and S-nitrosoglutathione (GSNO). This hypothesis was tested using deoxymyoglobin (MbFeII) to trap the expected HNO released from the target reaction, which should
Autor:
Matthew T. Jackson, Charles M. Garner, Maggie E. Jones, Patrick J. Farmer, Michael T. Spiegel, Kimberly A. Brien, Kevin K. Klausmeyer, Nathan C. Duncan, Barry Rich
Publikováno v:
Inorganica Chimica Acta. 473:180-185
Crystal structures of five first-row transition metal complexes of a recently-available bis-pyrazolylpyridine (bpp) ligand, 2,6-bis(3′,5′-diphenylpyrazolyl)pyridine (bdppp), prepared by reaction with transition metal chlorides, are reported. The
Mechanistic Investigations of Photoinduced Oxygenation of Ru(II) Bis-bipyridyl Flavonolate Complexes
Autor:
Lauren M. Harris, Kevin K. Klausmeyer, Amanda Hoogerbrugge, Patrick J. Farmer, Mukunda M. Ghimire, Mohammad A. Omary, Murugaeson R. Kumar, Xiaozhen Han
Publikováno v:
Inorganic Chemistry. 57:2416-2424
We previously reported that a Ru-bound flavonolate model of flavonol dioxygenases, [RuII(bpy)2(3-hydroxyfla)][PF6], photochemically reacts with dioxygen in two different manners. Broad-band excitation generates mixtures of products characteristic of
Autor:
Shamus Truksa, Patrick J. Farmer, Andrew G. Smith, Kevin K. Klausmeyer, Michael T. Spiegel, Kevin L. Shuford, Amanda Hoogerbrugge
Publikováno v:
Dalton Transactions. 47:9030-9037
We report an efficient, one-step synthesis of the chelator 3-hydroxy-2-methyl-4-selenopyrone (selenomaltol). Complexes of selenomaltol with Fe(iii), Ni(ii), Cu(ii) and Zn(ii) have been prepared and studied by NMR, X-ray crystallography, cyclic voltam