Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Patrick J. Dunn"'
Autor:
Andrea Comba, Maria Luisa Varela, Syed M. Faisal, Clifford C. Abel, II, Anna E. Argento, Wajd N. Al-Holou, Todd C. Hollon, Jacqueline D. Perelman, Patrick J. Dunn, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102174- (2023)
Summary: Development of spatial-integrative pre-clinical models is needed for glioblastoma, which are heterogenous tumors with poor prognosis. Here, we present an optimized protocol to generate three-dimensional ex vivo explant slice glioma model fro
Externí odkaz:
https://doaj.org/article/2c43e2be55634ce0ab0275ab171a6f0b
Autor:
Andrea Comba, Syed M. Faisal, Patrick J. Dunn, Anna E. Argento, Todd C. Hollon, Wajd N. Al-Holou, Maria Luisa Varela, Daniel B. Zamler, Gunnar L. Quass, Pierre F. Apostolides, Clifford Abel, Christine E. Brown, Phillip E. Kish, Alon Kahana, Celina G. Kleer, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
It is essential to improve our understanding of the features that influence aggressiveness and invasion in high grade gliomas (HGG). Here, the authors characterize dynamic anatomical structures in HGG called oncostreams, which are associated with tum
Externí odkaz:
https://doaj.org/article/3b351a9de1174a41bae1168e3664c972
Autor:
Elizabeth J. Salm, Patrick J. Dunn, Lili Shan, Miwako Yamasaki, Nathalie M. Malewicz, Taisuke Miyazaki, Joongkyu Park, Akio Sumioka, R. Richard L. Hamer, Wei-Wu He, Megumi Morimoto-Tomita, Robert H. LaMotte, Susumu Tomita
Publikováno v:
Cell Reports, Vol 31, Iss 9, Pp - (2020)
Summary: Fast purinergic signaling is mediated by ATP and ATP-gated ionotropic P2X receptors (P2XRs), and it is implicated in pain-related behaviors. The properties exhibited by P2XRs vary between those expressed in heterologous cells and in vivo. Se
Externí odkaz:
https://doaj.org/article/989eda6db00a41328abe0881dd92de9a
Autor:
Patrick J. Dunn, Hadi Danawi
Digital health tools have been used in a wide variety of healthcare services including promoting healthy behaviors and improving health outcomes in people with chronic conditions including cardiovascular disease. However, there is no “one size fits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5fe483d67ccec108ea3a1b00d7e1c93
https://doi.org/10.4018/978-1-7998-9490-2.ch006
https://doi.org/10.4018/978-1-7998-9490-2.ch006
Autor:
Andrea Comba, Syed Faisal, Patrick J. Dunn, Anna E. Argento, Todd C. Hollon, Wajd N. Al-Holou, Maria L. Varela, Daniel B. Zamler, Gunnar L. Quass, Pierre F. Apostolides, Christine E. Brown, Phillip E. E. Kish, Alon Kahana, Celina G. Kleer, Sebastien Motsch, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
Cancer Research. 82:2476-2476
Glioblastomas multiforme (GBMs) are the most lethal tumors of the brain. Tumoral mesenchymal transformation is a hallmark of GBMs associated with alterations in cellular morphology and dynamic organization. However, little is known about the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afb77c3bd64dfe2beacb84bec2850734
https://doi.org/10.1158/1538-7445.am2022-2476
https://doi.org/10.1158/1538-7445.am2022-2476
Autor:
Andrea Comba, Syed M. Faisal, Patrick J. Dunn, Anna E. Argento, Todd C. Hollon, Wajd N. Al-Holou, Maria Luisa Varela, Daniel B. Zamler, Gunnar L Quass, Pierre F. Apostolides, Clifford Abel, Christine E. Brown, Phillip E. Kish, Alon Kahana, Celina G. Kleer, Sebastien Motsch, Maria G Castro, Pedro R. Lowenstein
Intra-tumoral heterogeneity and diffuse infiltration are hallmarks of glioblastoma that challenge treatment efficacy. However, the mechanisms that set up both tumor heterogeneity and invasion remain poorly understood. Herein, we present a comprehensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba7efacd60c014926db1fa75a4e7e734
https://doi.org/10.1101/2020.12.01.404970
https://doi.org/10.1101/2020.12.01.404970
Autor:
Andrea Comba, Patrick J Dunn, Anna E Argento, Padma Kadiyala, Maria Ventosa, Priti Patel, Daniel B Zamler, Felipe J Nunez, Lili Zhao, Maria G Castro, Pedro R Lowenstein
Publikováno v:
Neuro-Oncology. 23:1413-1413
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdf23ce08c21d3633880e68bdaee593a
https://doi.org/10.1093/neuonc/noaa063
https://doi.org/10.1093/neuonc/noaa063
Autor:
Zhen, Chen, Wakana, Mori, Xiaofei, Zhang, Tomoteru, Yamasaki, Patrick J, Dunn, Genwei, Zhang, Hualong, Fu, Tuo, Shao, Yiding, Zhang, Akiko, Hatori, Longle, Ma, Masayuki, Fujinaga, Lin, Xie, Xiaoyun, Deng, Hua, Li, Qingzhen, Yu, Jian, Rong, Lee, Josephson, Jun-An, Ma, Yihan, Shao, Susumu, Tomita, Ming-Rong, Zhang, Steven H, Liang
Publikováno v:
European journal of medicinal chemistry. 157
a-Amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are implicated in the pathology of neurological diseases such as epilepsy and schizophrenia. As pan antagonists for this target are often accompanied with undesired effects at hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b13c6d39d7674855365a1884dde58b9
https://pubmed.ncbi.nlm.nih.gov/30145376
https://pubmed.ncbi.nlm.nih.gov/30145376
Autor:
Patrick J Dunn
Publikováno v:
Stellenbosch Theological Journal, Volume: 2, Issue: 2, Pages: 39-56, Published: 2016
Across the Global South, contemporary Christian theology is grappling with the best way to understand and respond to the rise of neo-Pentecostalism and the associated emphasis on charismatic experience. Speaking from a vastly different contest, the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a39ac34aef486a9c090d6636a6d34dd
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S2413-94672016000200004&lng=en&tlng=en
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S2413-94672016000200004&lng=en&tlng=en
Autor:
Patrick J Dunn, Joseph H. Nadeau
Publikováno v:
Current Opinion in Genetics & Development. 8:311-315
A major challenge in genetics research is defining and dissecting the diversity of developmental and physiological pathways that lie between genes and traits. New functional genomics methods are transforming these studies by providing comprehensive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a158bdf3baad781401276d4e3e2eeb
https://doi.org/10.1016/s0959-437x(98)80087-7
https://doi.org/10.1016/s0959-437x(98)80087-7