Výsledky vyhledávání - "Patrick J. Daniels"

Dynamics of the metal-dependent transcription factor complex in vivo at the mouse metallothionein-I promoter

Autor: Glen K. Andrews, Patrick J. Daniels

Publikováno v: Nucleic Acids Research. 31:6710-6721

The in vivo association of transcription factors with the metallothionein-I promoter was examined using chromatin immunoprecipitation (ChIP) assays. The results demonstrated that c-fos is rapidly recruited along with the metal response element-bindin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9080c07ea895eeaef1c136ebbfd88138
https://doi.org/10.1093/nar/gkg913

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Mammalian metal response element-binding transcription factor-1 functions as a zinc sensor in yeast, but not as a sensor of cadmium or oxidative stress

Autor: Irina V. Smirnova, Dennis R. Winge, Glen K. Andrews, Patrick J. Daniels, Doug Bittel

Publikováno v: Nucleic Acids Research. 30:3130-3140

The zinc finger protein, metal response element-binding transcription factor-1 (MTF-1) regulates the expression of genes in response to metal ions and oxidative stress. The precise mechanisms by which this occurs are not understood. To further examin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c3d9f00b17f8fd400b233443874d36
https://doi.org/10.1093/nar/gkf432

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Interferon-Mediated Block in Cell Cycle and Altered Integrin Expression in a Differentiated Salivary Gland Cell Line (HSG) Cultured on Matrigel

Autor: Steven Gustafson, William DePond, Patrick J. Daniels, Carole McArthur, Diana French, Yan Wang

Publikováno v: Journal of Interferon & Cytokine Research. 20:1101-1109

Sjögren's syndrome (SS), an idiopathic, autoimmune exocrinopathy, is partly characterized by diminished salivary flow, acinar cell atrophy, and increased expression of several cytokines. Several in vivo characteristics of the sialoadenitis are also

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708190e9dca42d981dd0b9858cb888a4
https://doi.org/10.1089/107999000750053771

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The Transcription Factor MTF-1 Mediates Metal Regulation of the Mouse ZnT1 Gene

Autor: Rudravajhala Ravindra, S. Joshua Langmade, Glen K. Andrews, Patrick J. Daniels

Publikováno v: Journal of Biological Chemistry. 275:34803-34809

Metal regulation of the mouse zinc transporter (ZnT)-1 gene was examined in cultured cells and in the developing conceptus. Zinc or cadmium treatment of cell lines rapidly (3 h) and dramatically (about 12-fold) induced ZnT1 mRNA levels. In cells incu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fcc9fd4375cb05e71f5e9b68b2c3b7
https://doi.org/10.1074/jbc.m007339200

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Sjögren’s Syndrome Salivary Gland Immunopathology: Increased Laminin Expression Precedes Lymphocytic Infiltration

Autor: Peter J. Kragel, Linda Julian, Paul Howard, Carole McArthur, Patrick J. Daniels

Publikováno v: Journal of Autoimmunity. 10:59-65

Previous studies have demonstrated increased expression of a laminin-like protein in labial salivary glands from Sjogren’s syndrome (SS) patients. The objective of the present study was to verify the identity of this protein and to compare lymphocy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ff68536f9e248d374d0a1d8c31b472
https://doi.org/10.1006/jaut.1996.0109

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Expressed phosphorylase b kinase and its alphagammadelta subcomplex as regulatory models for the rabbit skeletal muscle holoenzyme

Autor: Priyadarsini Kumar, Igor G. Boulatnikov, Jennifer L. Peters, Donal A. Walsh, Patrick J. Daniels, Owen W. Nadeau, Jessica M. Sage, Gerald M. Carlson

Publikováno v: Biochemistry. 48(42)

Phosphorylase b kinase (PhK),1 a hexadecameric enzyme complex with (αβγδ)4 subunit stoichiometry (1), controls glycogen degradation via phosphorylation of glycogen phosphorylase b (GPb). The kinase activity, which resides on the catalytic γ subu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9136decbeafb4a90252785eff9bc880c
https://pubmed.ncbi.nlm.nih.gov/19764815

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The Regulatory β Subunit of Phosphorylase Kinase Interacts with Glyceraldehyde‐3‐phosphate Dehydrogenase

Autor: Jessica M. Sage, Antonio Artigues, Marina D. Jeyasingham, Igor G. Boulatnikov, Owen W. Nadeau, Gerald M. Carlson, Maria T. Villar, Patrick J. Daniels

Publikováno v: The FASEB Journal. 21

Phosphorylase kinase (ATP:phosphorylase b phosphotransferase, EC 2.7.1.38), hereafter termed PhK,1 is in fast-twitch skeletal muscle a hexadecameric complex with a subunit composition of (αβγδ)4 and a mass of 1.3 × 106 Da (reviewed in ref 1). Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe2cbbe4af5a59c0efa5fb056bb4b08
https://doi.org/10.1096/fasebj.21.5.a276-b

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Putative zinc-sensing zinc fingers of metal-response element-binding transcription factor-1 stabilize a metal-dependent chromatin complex on the endogenous metallothionein-I promoter

Autor: Huimin Jiang, Glen K. Andrews, Patrick J. Daniels

Publikováno v: The Journal of biological chemistry. 278(32)

The metalloregulatory functions of metal-response element-binding transcription factor-1 (MTF-1) have been mapped, in part, to its six highly conserved zinc fingers. Here we examined the ability of zinc finger deletion mutants of mouse MTF-1 to regul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941f0d83830823bea7c3fb7df3465083
https://pubmed.ncbi.nlm.nih.gov/12764133

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