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pro vyhledávání: '"Patrick J. Costa"'
Publikováno v:
Molecular and Cellular Biology. 27:2800-2811
Proper transcription by RNA polymerase II is dependent on the modification state of the chromatin template. The Paf1 complex is associated with RNA polymerase II during transcription elongation and is required for several histone modifications that m
Autor:
Derek L. Lindstrom, Kelli L. Roinick, Grant A. Hartzog, Karen M. Arndt, Hien G. Tran, Alexander D. Johnson, Patrick J. Costa, Rajna Simic
Publikováno v:
The EMBO Journal. 22:1846-1856
Transcription in eukaryotes is influenced by the chromatin state of the template, and chromatin remodeling factors have well-documented roles in regulating transcription initiation by RNA polymerase (pol) II. Chromatin also influences transcription e
Autor:
Jennifer L. Jennings, Derek L. Lindstrom, Rajna Simic, Patrick J. Costa, Andrew J. Link, Sharon L. Squazzo, Kathryn E. Kumer, Grant A. Hartzog, Karen M. Arndt
We are using biochemical and genetic approaches to study Rtf1 and the Spt4–Spt5 complex, which independently have been implicated in transcription elongation by RNA polymerase II. Here, we report a remarkable convergence of these studies. First, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af05c7a4e075c486380e2cd9b04918f6
https://europepmc.org/articles/PMC125365/
https://europepmc.org/articles/PMC125365/
Autor:
Patrick J. Costa, Karen M. Arndt
Publikováno v:
Genetics. 156(2)
Strong evidence indicates that transcription elongation by RNA polymerase II (pol II) is a highly regulated process. Here we present genetic results that indicate a role for the Saccharomyces cerevisiae Rtf1 protein in transcription elongation. A scr