Successive Bloodmeals Enhance Virus Dissemination within Mosquitoes and Increase Transmission Potential

Autor: Joshua L. Warren, Doug E. Brackney, Tereza Magalhaes, Megan R. Miller, Angela Bransfield, Patrick J. Conway, John J. Shepard, Philip M. Armstrong, Michael J. Misencik, Brian D. Foy, Theodore G. Andreadis, Virginia E. Pitzer, Hanna Y. Ehrlich, Andrea Gloria-Soria

Publikováno v: Nature microbiology

The recent Zika virus (ZIKV) and chikungunya virus epidemics highlight the explosive nature of arthropod-borne viruses (arboviruses) transmitted by Aedes spp. mosquitoes1,2. Vector competence and the extrinsic incubation period (EIP) are two key ento

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f4e902259d828fcf9df03d55e3af5f
http://europepmc.org/articles/PMC7199921

Abstract 3156: Over-expression of CEACAM6 negatively modulates the tumor microenvironment in pancreatic cancer

Autor: Aisha Al-Khinji, Yuliang Chen, Patrick J. Conway, Daruka Mahadevan, Ritu Pandey, Mihir Patil

Publikováno v: Cancer Research. 81:3156-3156

Background: CEACAM6 is a cell adhesion receptor of the Ig-family over-expressed exclusively in primates and human pancreatic ductal adenocarcinoma (PDA). It is present in all subtypes and is enriched classical activated stroma subtype. CEACAM6 has mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54adc249a180b344d2874054f21ee61c
https://doi.org/10.1158/1538-7445.am2021-3156

Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial

Autor: Susan Gunn, Stephanie Guilford, Lisa Sulkowski, Shannon E. G. Hamrick, David P. Carlton, Cathy Grisby, Sara B. De Mauro, Scott A. McDonald, Amir M. Khan, Christine A. Gleason, Jeffrey L. Segar, Sandra Grimes, William E. Truog, Lenora Jackson, Conra Backstrom Lacy, Cheri Gauldin, Kimberley A. Fisher, Carmen Garcia, Jacky R. Walker, Nancy S. Newman, Brenda B. Poindexter, Nirupama Laroia, Monica V. Collins, Jonathan M. Klein, Ellen C. Hale, Jeffrey R. Parker, Emilee Little, Tracy L. Nolen, Carol K. Redmond, Sandra Sundquist Beauman, Namasivayam Ambalavanan, Toni Mancini, Richard A. Polin, Aasma S. Chaudhary, Janice Bernhardt, Athina Pappas, Alexis S. Davis, Emma Ramon, Kathleen Weingarden, Laura Sumner, Edward F. Bell, Edward G. Shepherd, Karen J. Johnson, Beena G. Sood, Holly I.M. Wadkins, Robert D. Roghair, Patrick J. Conway, Julie Arldt-McAlister, Mary E. Johnson, Kevin Dysart, Myra H. Wyckoff, Lina F. Chalak, Ann Marie Scorsone, Donia B. Campbell, Rebecca Bara, Howard W. Kilbride, Anne Marie Reynolds, Dennis Wallace, Soraya Abbasi, Satyanarayana Lakshminrusimha, Carl L. Bose, Jon E. Tyson, Kathy Johnson, Ronnie Guillet, Robert T. Burke, Sharon L. Wright, Jeanette O'Donnell Auman, Teresa Chanlaw, Glenda K. Rabe, Suhas G. Kallapur, Ashley Williams, Gail E. Besner, Elisa Vierira, Stephanie Wilson Archer, Waldemar A. Carlo, Greg Muthig, Leslie T. McKinley, Sandra Wuertz, Shirley S. Cosby, Kristin Kirker, Melinda S. Proud, Melinda Caskey, Angelita M. Hensman, Kimberly Hayes-Hart, Karen Martin, Claudia Pedroza, Eugenia K. Pallotto, Carolyn M. Petrie Huitema, Lauritz R. Meyer, Jane E. Brumbaugh, Patricia Luzader, Jamie E. Newman, Georgia E. McDavid, Joanne Finkle, Meena Garg, Carl T. D'Angio, Vipinchandra Bhavsar, Krisa P. Van Meurs, Anne Holmes, Sudarshan R. Jadcherla, Ross Sommers, John D.E. Barks, Rosemary D. Higgins, Traci E Clemons, Leslie Dawn Wilson, Michael G. Sacilowski, Karen A. Wynn, Martin Keszler, Kristi L. Watterberg, Nicole Walker, Christine A. Fortney, Stephanie A. Wiggins, Cary R. Murphy, Marian Willinger, Michael S. Caplan, Betty R. Vohr, Rachel Geller, Ronald N. Goldberg, Margaret M. Crawford, Lucy Smiley, Steven J. Weiner, Dara M. Cucinotta, Barbara Schmidt, Mary E. D'Alton, Tarah T. Colaizy, John M. Dagle, Robin K. Ohls, Gregory M Sokol, Yvonne Loggins, Katrina Burson, Luc P. Brion, Kathleen A. Kennedy, Pablo J. Sánchez, Abbot R. Laptook, Ronald J. Wong, Roy J. Heyne, Anna Maria Hibbs, Haresh Kirpalani, Andrea Halbrook, Carol Kibler, Seetha Shankaran, Patti L. Pierce Tate, Carol H. Hartenberger, Steven J. McElroy, Dan L. Ellsbury, Diana M. Vasil, Teresa L. Gratton, Kurt Schibler, M. Bethany Ball, Michele C. Walsh, Nehal A. Parikh, Maria Batts, Abhik Das, Richard A. Ehrenkranz, Dianne E. Herron, Birju A. Shah, Marian M. Adams, Jenna Gabrio, Jennifer Jennings, Cindy Clark, Barbara J. Stoll, Robert J. Boyle, Matthew M. Laughon, Marie Gantz, Lilia C. De Jesus, Julie B. Lindower, U. Devaskar, Shawna Rodgers, Estelle E. Fischer, Kristin M. Zaterka-Baxter, Mary Christensen, David K. Stevenson, Lijun Chen, Michael G. Ross, Girija Natarajan, Nicholas Guerina, Barbara D. Alexander

Publikováno v: JAMA, vol 312, iss 24

Importance Hypothermia at 33.5°C for 72 hours for neonatal hypoxic ischemic encephalopathy reduces death or disability to 44% to 55%; longer cooling and deeper cooling are neuroprotective in animal models. Objective To determine if longer duration c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc1161ccd31cb7fbe9f4fa2939ba5e6
https://pubmed.ncbi.nlm.nih.gov/28295535

Nature, capital, and trade: A second look

Autor: Patrick J. Conway

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9484923069797c7503e5b08a4d187d3b
https://doi.org/10.1017/cbo9780511528392.003

Nucleophilic decomposition of α-disulfones

Autor: Paul Allen, Patrick J. Conway

Publikováno v: Canadian Journal of Chemistry. 47:873-877

The sulfur–sulfur bond of α-disulfones is attacked by hydroxide ion in alcohol to yield sulfinate and sulfonate ion by a second-order reaction, first order in each of the reactants. With aromatic disulfones the ρ value of the Hammett equation is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e76eb6c9bede63baf02efc384c9081a
https://doi.org/10.1139/v69-144