Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Patrick J. CASEY"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-14 (2024)
Abstract Cancer stem cells (CSCs) are a group of specially programmed tumor cells that possess the characteristics of perpetual cell renewal, increased invasiveness, and often, drug resistance. Hence, eliminating CSCs is a major challenge for cancer
Externí odkaz:
https://doaj.org/article/5f3eb008a80846799d0daea493b5cd97
Autor:
Lalitha Vaishnavi Subramanyan, Suhail Ahmed Kabeer Rasheed, Lijin Wang, Sujoy Ghosh, Michelle Shi Ning Ong, Manikandan Lakshmanan, Mei Wang, Patrick J. Casey
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-17 (2024)
Abstract GNA13 (Gα13) is one of two alpha subunit members of the G12/13 family of heterotrimeric G-proteins which mediate signaling downstream of GPCRs. It is known to be essential for embryonic development and vasculogenesis and has been increasing
Externí odkaz:
https://doaj.org/article/ee581b5189c0431d82a0f8403a268c6b
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-13 (2022)
Abstract Epithelial-to-mesenchymal transition (EMT) is a critical underpinning process for cancer progression, recurrence and resistance to drug treatment. Identification of new regulators of EMT could lead to the development of effective therapies t
Externí odkaz:
https://doaj.org/article/ff2fc420f33847cca4cdc9a0f4e84b59
Autor:
Michael T. Forrester, Douglas T. Hess, J. Will Thompson, Rainbo Hultman, M. Arthur Moseley, Jonathan S. Stamler, Patrick J. Casey
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 2, Pp 393-398 (2011)
Protein S-acylation is a major posttranslational modification whereby a cysteine thiol is converted to a thioester. A prototype is S-palmitoylation (fatty acylation), in which a protein undergoes acylation with a hydrophobic 16 carbon lipid chain. Al
Externí odkaz:
https://doaj.org/article/2f7b93eb409b49f38595ffb502bbfe7a
Autor:
Mei Wang, Patrick J. Casey, Wan Long Zhu, Jing Tsong Teh, Tin Fan Chai, Kanjoormana Aryan Manu
Pancreatic cancer remains one of the most difficult to treat human cancers despite recent advances in targeted therapy. Inhibition of isoprenylcysteine carboxylmethyltransferase (ICMT), an enzyme that posttranslationally modifies a group of proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc2f36fde2ec429d19ebc21816f8d69
https://doi.org/10.1158/1535-7163.c.6537619
https://doi.org/10.1158/1535-7163.c.6537619
Autor:
Mei Wang, Patrick J. Casey, Wan Long Zhu, Jing Tsong Teh, Tin Fan Chai, Kanjoormana Aryan Manu
Supplementary Fig. S1. ICMT inhibitor treatment leads to reduced viability in sensitive pancreatic cancer cell lines. (A) MTS viability assay that measures the total viable cells (OD measured at 490 nm) at the time of initiation (0 hr) and end (48 hr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5370f28f579c727bd43adfbd0a69fb
https://doi.org/10.1158/1535-7163.22504090
https://doi.org/10.1158/1535-7163.22504090
Supplementary Table 1 from Activation of Rap1 Promotes Prostate Cancer Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072be74220541f57cc5a68ea0ab30282
https://doi.org/10.1158/0008-5472.22377656
https://doi.org/10.1158/0008-5472.22377656
Supplementary Figure 1 from Activation of Rap1 Promotes Prostate Cancer Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9006ef35dd3a11758e3f2f23131d5f0a
https://doi.org/10.1158/0008-5472.22377665.v1
https://doi.org/10.1158/0008-5472.22377665.v1
Supplementary Methods from Activation of Rap1 Promotes Prostate Cancer Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a6f57a8006717e9d45221d19dad957
https://doi.org/10.1158/0008-5472.22377662.v1
https://doi.org/10.1158/0008-5472.22377662.v1
Autor:
Patrick J. Casey
Publikováno v:
The Encyclopedia of Philosophy of Religion. :1-20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2edf603a8f62f0df44c084ca6d8e19df
https://doi.org/10.1002/9781119009924.eopr0165
https://doi.org/10.1002/9781119009924.eopr0165