Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Patrick J. C. May"'
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Lifetime experiences and lifestyle, such as education and engaging in leisure activities, contribute to cognitive reserve (CR), which delays the onset of age-related cognitive decline. Word-finding difficulties have been identified as the most promin
Externí odkaz:
https://doaj.org/article/21d5140e03474d24b84f1b866ad5d4bb
Autor:
Patrick J. C. May
Publikováno v:
Frontiers in Human Neuroscience, Vol 15 (2021)
An unpredictable stimulus elicits a stronger event-related response than a high-probability stimulus. This differential in response magnitude is termed the mismatch negativity (MMN). Over the past decade, it has become increasingly popular to explain
Externí odkaz:
https://doaj.org/article/25e6dc2b170b45168acd7117d8f2ee5e
Publikováno v:
The Journals of Gerontology: Series B. 78:777-788
The World Health Organization (WHO) aims to improve our understanding of the factors that promote healthy cognitive aging and combat dementia. Aging theories that consider individual aging trajectories are of paramount importance to meet the WHO’s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8514fe57b47396a93e31c9f47fc10c20
https://doi.org/10.1093/geronb/gbac197
https://doi.org/10.1093/geronb/gbac197
Publikováno v:
Biological cybernetics, 116(4):475-499
Adaptation, the reduction of neuronal responses by repetitive stimulation, is a ubiquitous feature of auditory cortex (AC). It is not clear what causes adaptation, but short-term synaptic depression (STSD) is a potential candidate for the underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f44591ad828dd87012777e58edd27d6
https://repository.publisso.de/resource/frl:6434181
https://repository.publisso.de/resource/frl:6434181
Autor:
Stephanie L. Stout, Leonard L. Winneroski, Jorg Hendle, Warren J. Porter, Patrick J. C. May, Leonard N. Boggs, Thomas K. Baker, James P. Beck, Steven James Green, Anthony R. Borders, Erik James Hembre, Stephen L. Lowe, Christopher D Aluise, David L. McKinzie, Brian Morgan Watson, Brian Michael Mathes, Jon A. Erickson, Zhixiang Yang, Patrick J Cocke, Dustin J. Mergott, Brian A. Willis, Scott A. Monk, Pablo Garcia-Losada, David E. Timm, Richard A. Brier, Jose Eduardo Lopez
Publikováno v:
Journal of medicinal chemistry. 64(12)
The beta-site APP cleaving enzyme 1, known as BACE1, has been a widely pursued Alzheimer's disease drug target owing to its critical role in the production of amyloid-beta. We have previously reported the clinical development of LY2811376 and LY28867
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698057ee408d2f35c662510d099e51b3
https://pubmed.ncbi.nlm.nih.gov/34081466
https://pubmed.ncbi.nlm.nih.gov/34081466
Publikováno v:
Biological Cybernetics
Biological cybernetics, 113(3):321-345
Biological cybernetics, 113(3):321-345
Event-related fields of the magnetoencephalogram are triggered by sensory stimuli and appear as a series of waves extending hundreds of milliseconds after stimulus onset. They reflect the processing of the stimulus in cortex and have a highly subject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2899a266db3730f1913f0315641fef96
https://doi.org/10.1007/s00422-019-00795-9
https://doi.org/10.1007/s00422-019-00795-9
Publikováno v:
Psychophysiology, 58(4):e13769
Auditory event-related fields (ERFs) measured with magnetoencephalography (MEG) are useful for studying the neuronal underpinnings of auditory cognition in human cortex. They have a highly subject-specific morphology, albeit certain characteristic de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155253658f0df9a48fdfbd2ddd71e30b
https://zenodo.org/record/4537089
https://zenodo.org/record/4537089
Adaptation, the reduction of neuronal responses by repetitive stimulation, is a ubiquitous feature of auditory cortex (AC). It is not clear what causes adaptation, but short-term synaptic depression (STSD) is a potential candidate for the underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018a4ce4a31e9ec9e5b9845075555aae
Describing complex cells in primary visual cortex: a comparison of context and multifilter LN models
Autor:
Johan Westö, Patrick J. C. May
Publikováno v:
Journal of Neurophysiology. 120:703-719
Receptive field (RF) models are an important tool for deciphering neural responses to sensory stimuli. The two currently popular RF models are multifilter linear-nonlinear (LN) models and context models. Models are, however, never correct, and they r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557d5b212752653ef13e0440490d52da
https://doi.org/10.1152/jn.00916.2017
https://doi.org/10.1152/jn.00916.2017
Publikováno v:
NEURAL COMPUTATION. 28(2):327-353
Robust representations of sounds with a complex spectrotemporal structure are thought to emerge in hierarchically organized auditory cortex, but the computational advantage of this hierarchy remains unknown. Here, we used computational models to stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17cbe0699ad076a7a442d1e80aed9e3d
http://juuli.fi/Record/0274645316
http://juuli.fi/Record/0274645316