Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Patrick J. Branigan"'
Autor:
Andrew Blauvelt, Yanqing Chen, Patrick J. Branigan, Xuejun Liu, Samuel DePrimo, Brice E. Keyes, Monica Leung, Steven Fakharzadeh, Ya-Wen Yang, Ernesto J. Muñoz-Elías, James G. Krueger, Richard G. Langley
Publikováno v:
JID Innovations, Vol 4, Iss 5, Pp 100297- (2024)
IL-23 is a cytokine produced by myeloid cells that drives the T helper 17 pathway and plays an essential role in the pathophysiology of plaque psoriasis. IL-23 activation initiates a cascade of cytokines subsequently inducing the expression of many p
Externí odkaz:
https://doaj.org/article/3cdb3a1625bb4d1bb4480d62cb6cb130
Autor:
Andrew Blauvelt, Richard G. Langley, Patrick J. Branigan, Xuejun Liu, Yanqing Chen, Samuel DePrimo, Keying Ma, Brittney Scott, Kim Campbell, Ernesto J. Muñoz-Elías, Kim A. Papp
Publikováno v:
JID Innovations, Vol 4, Iss 5, Pp 100287- (2024)
Background: Psoriasis is an immune-mediated inflammatory disease characterized by activation of IL-23–driven IL-17–producing T cell and other IL-23 receptor–positive IL-17–producing cell responses. Selective blockade of IL-23p19 with guselkum
Externí odkaz:
https://doaj.org/article/b95df6bc33d542458a2fcbb40566670b
Autor:
Jörg Menche, Emre Guney, Amitabh Sharma, Patrick J. Branigan, Matthew J. Loza, Frédéric Baribaud, Radu Dobrin, Albert-László Barabási
Publikováno v:
npj Systems Biology and Applications, Vol 3, Iss 1, Pp 1-10 (2017)
Molecular Medicine: Personalized expression profiles elucidate disease heterogeneity A comparison of gene expression profiles of different patients with the same disease reveals a combinatorial model for disease heterogeneity. A framework is develope
Externí odkaz:
https://doaj.org/article/edd0162ab2264d08b9f3fbaea8989ba2
Autor:
Joseph B. Domachowske, Danning Huang, Helene F. Rosenberg, Dongliang Wang, Patrick J. Branigan, Manika Suryadevara, Christy M. Tabarani, Cynthia A. Bonville
Publikováno v:
The Pediatric Infectious Disease Journal
Background Virus-induced inflammation contributes to respiratory syncytial virus (RSV) pathogenesis. We sought to determine the specific mediators that are associated with more severe illness in young children. Methods Children ≤ 5 years of age see
Autor:
Samuel Baker, Jyoti Rao, Daniel Baker, H. Ralph Schumacher, Zhao-heng Meng, Patrick J. Branigan, Jaeho Park
Publikováno v:
Inflammopharmacology. 8:113-121
Subacute and chronic CPPD crystal induced inflammation can be difficult to manage. We have used the rat subcutaneous air pouch to study the treatment of experimental CPPD crystal induced inflammation with hydroxychloroquine. The drug was given by gav
Autor:
Alan P. Hudson, Hervé C. Gérard, Patrick J. Branigan, Thurayya Arayssi, H. Ralph Schumacher, Shigeru Kotake, John H. Klippel, Cheryl Yarboro, Ronald L. Wilder
Publikováno v:
Infection and Immunity. 67:2682-2686
Genetically determined differences in interleukin-10 (IL-10) and gamma interferon (IFN-γ) responses in mice correlate with clearance of Chlamydia pneumonitis infection. We measured the synovial expression of IL-10 and IFN-γ and additional cytokine
Autor:
Christine M Heath, Alan P. Hudson, Hervé C. Gérard, Patrick J. Branigan, Shahab S Minassian, Gulnar R Balsara
Publikováno v:
Fertility and Sterility. 70:945-948
Objective: To use standard molecular methods to define the prevalence and metabolic characteristics of Chlamydia trachomatis during infection of fallopian tubes in women with ectopic pregnancies. Design: Polymerase chain reaction (PCR)- and reverse t
Autor:
Hervé C. Gérard, Lars Köhler, Henning Zeidler, Alan P. Hudson, Patrick J. Branigan, H. Ralph Schumacher
Publikováno v:
Medical Microbiology and Immunology. 187:115-120
The principal host cell for persistently infecting synovial Chlamydia trachomatis is the macrophage. During infection of human monocytes/macrophages in culture this bacterium displays aberrant morphology and produces no new elementary bodies, reflect
Autor:
Patrick J. Branigan, Alan P. Hudson, Denah M. Appelt, Brian J. Balin, J. Todd Abrams, Hervé C. Gérard, Judith A. Whittum-Hudson, E. James Arking
Publikováno v:
Medical Microbiology and Immunology. 187:23-42
We assessed whether the intracellular bacterium Chlamydia pneumoniae was present in post-mortem brain samples from patients with and without late-onset Alzheimer's disease (AD), since some indirect evidence seems to suggest that infection with the or
Autor:
Cynthia A. Bonville, Joseph B. Domachowske, Helene F. Rosenberg, Patrick J. Branigan, Manika Suryadevera, Lindsay McGann, Rana E. El Feghaly
Publikováno v:
The Pediatric Infectious Disease Journal
To describe the clinical manifestations of parainfluenza virus (PIV) infection and to characterize biochemical markers of PIV disease severity.We reviewed the medical records of 165 children who had a nasal wash culture positive for PIV at our instit