Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Patrick J., Farmer"'
Autor:
Murugaeson R. Kumar, Patrick J. Farmer
Publikováno v:
Redox Biology, Vol 14, Iss , Pp 485-491 (2018)
Small oxoacids of sulfur (SOS) are elusive molecules like sulfenic acid, HSOH, and sulfinic acid, HS(O)OH, generated during the oxidation of hydrogen sulfide, H2S, in aqueous solution. Unlike their alkyl homologs, there is a little data on their gene
Externí odkaz:
https://doaj.org/article/8e717e01b7ee47d69224e75330469c07
Autor:
Ottis Scrivner, Ahmed Ismaeel, Murugaeson R. Kumar, Kristina Sorokolet, Panagiotis Koutakis, Patrick J. Farmer
Publikováno v:
Molecules, Vol 26, Iss 23, p 7160 (2021)
Hydrogen sulfide (H2S) is an endogenous signaling molecule which is important for cardiovascular health, but its mechanism of action remains poorly understood. Here, we report measurements of H2S as well as its oxidized metabolites, termed small oxoa
Externí odkaz:
https://doaj.org/article/119eb90b657c4c8994a550bdf5610770
Autor:
Ottis Scrivner, Kristina Sorokolet, Bessie W. Kebaara, Murugaeson R. Kumar, Patrick J. Farmer, Angelo Wong
Publikováno v:
ACS Chemical Biology. 16:1413-1424
This report characterizes and quantifies endogenous hydrogen sulfide (H2S) and small oxoacids of sulfur (SOS = HOSH, HOSOH) in a panel of cell lines including human cancer (A375 melanoma cells, HeLa cervical cells) and noncancer (HEK293 embryonic kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f34e7da1350e4850faf1bdbb8e84c9a8
https://doi.org/10.1021/acschembio.1c00257
https://doi.org/10.1021/acschembio.1c00257
Autor:
Murugaeson R Kumar, Patrick J Farmer
Publikováno v:
Molecules, Vol 24, Iss 17, p 3090 (2019)
Glutathione-based products, GSnX, of the reaction of hydrogen sulfide, H2S, S-nitroso glutathione, and GSNO, at varied stoichiometries have been analyzed by liquid chromatography high-resolution mass spectrometry (LC-HRMS) and chemical trapping exper
Externí odkaz:
https://doaj.org/article/3b66e34df55f4ef8b96f4b45ec62906f
Autor:
Ottis Scrivner, Long Dao, M Karen Newell-Rogers, Babbak Shahandeh, Frank L Meyskens, Susan Kurumi Kozawa, Feng Liu-Smith, Germán Plascencia-Villa, Miguel José-Yacamán, Shang Jia, Christopher J Chang, Patrick J Farmer
Publikováno v:
Metallomics
Metallomics : integrated biometal science, vol 14, iss 1
Metallomics : integrated biometal science, vol 14, iss 1
In this report, we investigate the toxicity of the ionophore thiomaltol (Htma) and Cu salts to melanoma. Divalent metal complexes of thiomaltol display toxicity against A375 melanoma cell culture resulting in a distinct apoptotic response at submicro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d831c10dc5fc209940ec12d9333f64d
https://pubmed.ncbi.nlm.nih.gov/34958363
https://pubmed.ncbi.nlm.nih.gov/34958363
Autor:
Alton Hassell, Touradj Solouki, Patrick J. Farmer, Ian G.M. Anthony, Matthew R. Brantley, Michael T. Spiegel
Publikováno v:
Energy & Fuels. 32:10549-10555
Comprehensive characterization and structural elucidation of specific chemical subclasses within a complex mixture often require analyte separation, a variety of spectroscopic techniques, and inqui...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66b7276fa35f0404d86472bb1c4f2690
https://doi.org/10.1021/acs.energyfuels.8b02342
https://doi.org/10.1021/acs.energyfuels.8b02342
Autor:
Touradj Solouki, Patrick J. Farmer, Tara Clover, Murugaeson R. Kumar, Abayomi D. Olaitan, Christopher Becker
Publikováno v:
Nitric Oxide. 77:96-105
Several recent reports suggest that HNO may be produced endogenously by reaction of H2S and S-nitrosoglutathione (GSNO). This hypothesis was tested using deoxymyoglobin (MbFeII) to trap the expected HNO released from the target reaction, which should
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a5206d43511d6ca5fed4318e8f3e24
https://doi.org/10.1016/j.niox.2018.04.012
https://doi.org/10.1016/j.niox.2018.04.012
Autor:
Matthew T. Jackson, Charles M. Garner, Maggie E. Jones, Patrick J. Farmer, Michael T. Spiegel, Kimberly A. Brien, Kevin K. Klausmeyer, Nathan C. Duncan, Barry Rich
Publikováno v:
Inorganica Chimica Acta. 473:180-185
Crystal structures of five first-row transition metal complexes of a recently-available bis-pyrazolylpyridine (bpp) ligand, 2,6-bis(3′,5′-diphenylpyrazolyl)pyridine (bdppp), prepared by reaction with transition metal chlorides, are reported. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c66d4ad641aee3aeeb0ecb52c20175bc
https://doi.org/10.1016/j.ica.2017.12.032
https://doi.org/10.1016/j.ica.2017.12.032
Mechanistic Investigations of Photoinduced Oxygenation of Ru(II) Bis-bipyridyl Flavonolate Complexes
Autor:
Lauren M. Harris, Kevin K. Klausmeyer, Amanda Hoogerbrugge, Patrick J. Farmer, Mukunda M. Ghimire, Mohammad A. Omary, Murugaeson R. Kumar, Xiaozhen Han
Publikováno v:
Inorganic Chemistry. 57:2416-2424
We previously reported that a Ru-bound flavonolate model of flavonol dioxygenases, [RuII(bpy)2(3-hydroxyfla)][PF6], photochemically reacts with dioxygen in two different manners. Broad-band excitation generates mixtures of products characteristic of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67349d6e6643dfc9d24d58e90f481f8
https://doi.org/10.1021/acs.inorgchem.7b01384
https://doi.org/10.1021/acs.inorgchem.7b01384
Autor:
Panagiotis Koutakis, Kristina Sorokolet, Ahmed Ismaeel, Ottis Scrivner, Patrick J. Farmer, Murugaeson R. Kumar
Publikováno v:
Molecules; Volume 26; Issue 23; Pages: 7160
Molecules, Vol 26, Iss 7160, p 7160 (2021)
Molecules, Vol 26, Iss 7160, p 7160 (2021)
Hydrogen sulfide (H2S) is an endogenous signaling molecule which is important for cardiovascular health, but its mechanism of action remains poorly understood. Here, we report measurements of H2S as well as its oxidized metabolites, termed small oxoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25c0b8e47bdf6fe3a0a63b467449bfb
https://doi.org/10.3390/molecules26237160
https://doi.org/10.3390/molecules26237160