Zobrazeno 1 - 10 of 103 pro vyhledávání: '"Patrick J Venables"'
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Akademický článek
Porphyromonas gingivalis facilitates the development and progression of destructive arthritis through its unique bacterial peptidylarginine deiminase (PAD).
Autor: Katarzyna J Maresz, Annelie Hellvard, Aneta Sroka, Karina Adamowicz, Ewa Bielecka, Joanna Koziel, Katarzyna Gawron, Danuta Mizgalska, Katarzyna A Marcinska, Malgorzata Benedyk, Krzysztof Pyrc, Anne-Marie Quirke, Roland Jonsson, Saba Alzabin, Patrick J Venables, Ky-Anh Nguyen, Piotr Mydel, Jan Potempa
Publikováno v: PLoS Pathogens, Vol 9, Iss 9, p e1003627 (2013)
Rheumatoid arthritis and periodontitis are two prevalent chronic inflammatory diseases in humans and are associated with each other both clinically and epidemiologically. Recent findings suggest a causative link between periodontal infection and rheu
Externí odkaz: https://doaj.org/article/a0922d2790624eb3aee8e6c974fa32fc
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Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis
Autor: Marie-Laëtitia Thézénas, N.A. Burgess-Brown, Roman Fischer, Patrick J Venables, Leela Shrestha, Anna B Montgomery, Wyatt W. Yue, Jolanta Kopec
Publikováno v: Annals of the Rheumatic Diseases
BackgroundPeriodontitis (PD) is a known risk factor for rheumatoid arthritis (RA) and there is increasing evidence that the link between the two diseases is due to citrullination by the unique bacterial peptidylarginine deiminase (PAD) enzyme express
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91009714b4b08847a71601c014b2f8fc
https://ora.ox.ac.uk/objects/uuid:6944c2a9-e1c6-4a1f-82b8-ea85eb3b80ee
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4
AB0290 Lower educational levels are associated with a higher risk of rheumatoid arthritis in a southern european nested case-control study
Autor: E. Riboli, Dora Romaguera, P. de Pablo, Amalia Mattiello, Salvatore Panico, Paolo Vineis, Diana Gavrila, Carlotta Sacerdote, Carmen Navarro, Rosario Tumino, W. E. R. Ollier, Patrick J Venables, Benjamin A Fisher
Publikováno v: Rheumatoid arthritis – prognosis, predictors and outcome.
Objectives To investigate the association between socioeconomic status (SES) on an individual level and incident RA Methods EPIC is a multicentre, pan-European prospective cohort study of apparently healthy populations. We undertook a nested case-con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f7f2b85934b926b9676336e3fb8c539
https://doi.org/10.1136/annrheumdis-2018-eular.6972
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Is Citrullination the Missing Link between Periodontal Disease and Rheumatoid Arthritis?
Autor: Anna B Montgomery, Patrick J Venables, Elena B. Lugli
Publikováno v: Current Oral Health Reports. 2:30-36
Connections between periodontitis (PD) and rheumatoid arthritis (RA) are suggested by an increased prevalence of PD in RA, shared environmental and genetic risk factors, and correlating levels of severity when the two diseases occur together. Here, w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d96b2ccf37aa9c9ce119339bc84d1bb0
https://doi.org/10.1007/s40496-014-0042-7
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03.25 Three enzymes co-expressed on the outer membrane of p.gingivalis, collaborate in breaking tolerance to citrullinated proteins
Autor: Ashish Patel, Sheri Saunders, Dominika Staniec, Anna B Montgomery, Ewa Cairns, Katarzyna Gawron, Patrick J Venables, Jan Potempa
Publikováno v: Immune regulation.
Introduction Periodontitis (PD) is an environmental risk factor for rheumatoid arthritis (RA), and there is increasing evidence that this is due to infection with Porphyromonas gingivalis. P. gingivalis expresses 3 candidate enzymes potentially capab
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8bdc6a059066631232c0b1fe4a27a81c
https://doi.org/10.1136/annrheumdis-2016-211049.25
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Porphyromonas gingivalis Peptidyl Arginine Deiminase : a Unique Bacterial PAD with Implications for Periodontal Disease and Rheumatoid Arthritis
Autor: Katarzyna Łazarz-Bartyzel, Katarzyna Gawron, Anna B Montgomery, Jan Potempa, Grzegorz Bereta, Patrick J Venables, Maria Chomyszyn-Gajewska
Publikováno v: Protein Deimination in Human Health and Disease ISBN: 9783319582436
Recently, peptidyl arginine deiminase from Porphyromonas gingivalis (PPAD) has become a subject of an intense research. Despite catalyzing the reaction of citrullination (deimination) and being a member of the guanidino-group modifying superfamily of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891eecc6b01ad565d7d03dd694f6857c
https://ruj.uj.edu.pl/xmlui/handle/item/120083
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Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis
Autor: Patrick J Venables, Shauna Culshaw, Bart C. Hamilton, A. Jimmy Ytterberg, Muslima Chowdhury, Ted R. Mikuls, Geoffrey M. Thiele, Elena B. Lugli, Peter Charles, Jan Potempa, Yonghua Guo, Roman A. Zubarev, Anne-Marie Quirke, Benjamin A Fisher, Natalia Wegner
Publikováno v: Annals of the Rheumatic Diseases; Vol 73
Annals of the Rheumatic Diseases
Background: Rheumatoid arthritis (RA) is characterised by autoimmunity to citrullinated proteins, and there is increasing epidemiologic evidence linking Porphyromonas gingivalis to RA. P gingivalis is apparently unique among periodontal pathogens in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d08315ebc12671284b78ba39c78ef9
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