Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Patrick J Dolph"'
Autor:
Ellen K Gagliani, Lisa M Gutzwiller, Yi Kuang, Yoshinobu Odaka, Phillipp Hoffmeister, Stefanie Hauff, Aleksandra Turkiewicz, Emily Harding-Theobald, Patrick J Dolph, Tilman Borggrefe, Franz Oswald, Brian Gebelein, Rhett A Kovall
Publikováno v:
PLoS Genetics, Vol 18, Iss 8, p e1010335 (2022)
Notch signaling is a conserved pathway that converts extracellular receptor-ligand interactions into changes in gene expression via a single transcription factor (CBF1/RBPJ in mammals; Su(H) in Drosophila). In humans, RBPJ variants have been linked t
Externí odkaz:
https://doaj.org/article/3d3ef8ff2e0245a7bfb1cb014a49f333
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 10, Pp 3139-3148 (2016)
Transvection—pairing-dependent interallelic regulation resulting from enhancer action in trans—occurs throughout the Drosophila melanogaster genome, likely as a result of the extensive somatic homolog pairing seen in Dipteran species. Recent stud
Externí odkaz:
https://doaj.org/article/7614ce7a6f714680b15fc89a1e917943
Autor:
Ronald D. Kinser, Patrick J. Dolph
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 3, Pp 655-662 (2012)
Endocytosis-mediated cell death is a form of degeneration displayed in several Drosophila mutants. This form of degeneration is displayed in several Drosophila mutant lines including flies lacking the eye-specific PLC (norpA). The cell death pathway
Externí odkaz:
https://doaj.org/article/10bad891679544f3a4d92c9e95f0d038
Autor:
Ellen K. Gagliani, Lisa M. Gutzwiller, Yi Kuang, Yoshinobu Odaka, Phillipp Hoffmeister, Stefanie Hauff, Aleksandra Turkiewicz, Emily Harding-Theobald, Patrick J. Dolph, Tilman Borggrefe, Franz Oswald, Brian Gebelein, Rhett A. Kovall
Publikováno v:
PLoS genetics. 18(8)
Notch signaling is a conserved pathway that converts extracellular receptor-ligand interactions into changes in gene expression via a single transcription factor (CBF1/RBPJ in mammals; Su(H) in Drosophila). In humans, RBPJ variants have been linked t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67dce116c72ecde6d05251bcac93ec40
https://pubmed.ncbi.nlm.nih.gov/35951645
https://pubmed.ncbi.nlm.nih.gov/35951645
Autor:
Ellen K. Gagliani, Brian Gebelein, Tilman Borggrefe, Yi Kuang, Patrick J. Dolph, Rhett A. Kovall, Phillipp Hoffmeister, Aleksandra Turkiewicz, Emily Harding-Theobald, Yoshinobu Odaka, Franz Oswald, Stefanie Hauff, Lisa M. Gutzwiller
Notch signaling is a conserved pathway that converts extracellular receptor-ligand interactions into changes in gene expression via a single transcription factor (CBF1/RBPJ in mammals; Su(H) in Drosophila). In humans, RBPJ variants have been linked t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48a3d161f94cc06c845756d7f7deccc1
https://doi.org/10.1101/2021.09.24.461537
https://doi.org/10.1101/2021.09.24.461537
Autor:
Sidhartha Dongre, Mikko Juusola, David Jaciuch, Xiaofeng Li, Diana Rien, Murali K. Bollepalli, Brian Chu, Zhuoyi Song, Lei Zheng, Roger C. Hardie, Patrick J. Dolph, Florence Blanchard, Anton Nikolaev, Ahmad N. Abou Tayoun, An Dau
Publikováno v:
The Journal of Neuroscience. 39:7132-7154
Ca2+-activated K+ channels (BK and SK) are ubiquitous in synaptic circuits, but their role in network adaptation and sensory perception remains largely unknown. Using electrophysiological and behavioral assays and biophysical modeling, we discover ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::503dbf41918ebb73eb20a4eb02b777f5
https://doi.org/10.1523/jneurosci.3213-18.2019
https://doi.org/10.1523/jneurosci.3213-18.2019
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34665 (2012)
A role for SK channels in synaptic plasticity has been very well-characterized. However, in the absence of simple genetic animal models, their role in behavioral memory remains elusive. Here, we take advantage of Drosophila melanogaster with its sing
Externí odkaz:
https://doaj.org/article/677bf50e760b4780a8192f2b5a4594d8
Publikováno v:
PLoS Genetics, Vol 5, Iss 2, p e1000377 (2009)
Progressive retinal degeneration is the underlying feature of many human retinal dystrophies. Previous work using Drosophila as a model system and analysis of specific mutations in human rhodopsin have uncovered a connection between rhodopsin endocyt
Externí odkaz:
https://doaj.org/article/45ab9916311b4865be51c6618aa9b5bd
Publikováno v:
PLoS Genetics, Vol 3, Iss 12, p e206 (2007)
The Drosophila melanogaster photoreceptor cell has long served as a model system for researchers focusing on how animal sensory neurons receive information from their surroundings and translate this information into chemical and electrical messages.
Externí odkaz:
https://doaj.org/article/01d7381071ef40f5b251b608f452539d
Autor:
Xiaofeng, Li, Ahmad, Abou Tayoun, Zhuoyi, Song, An, Dau, Diana, Rien, David, Jaciuch, Sidhartha, Dongre, Florence, Blanchard, Anton, Nikolaev, Lei, Zheng, Murali K, Bollepalli, Brian, Chu, Roger C, Hardie, Patrick J, Dolph, Mikko, Juusola
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(36)
Ca(2+)-activated K(+) channels (BK and SK) are ubiquitous in synaptic circuits, but their role in network adaptation and sensory perception remains largely unknown. Using electrophysiological and behavioral assays and biophysical modeling, we discove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::387f792ea26d7119e3240fba7f7c2534
https://pubmed.ncbi.nlm.nih.gov/31350259
https://pubmed.ncbi.nlm.nih.gov/31350259