Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Patrick J, Rochette"'
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Ultraviolet radiation (UVR) is a major environmental mutagen. In skin, UVR can initiate cancer through the induction of mutagenic DNA damage and promote its progression. An important cancer prevention mechanism is the regulated cell death (R
Externí odkaz:
https://doaj.org/article/014e8c2a674d49068b39f43dce225ab6
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Skin aging is a multifactorial process influenced by internal and external factors. The contribution of different environmental factors has been well established individually in the last few years. On the one hand, man is rarely exposed to a
Externí odkaz:
https://doaj.org/article/f2a1caf34c6a4049a028a77356063844
Autor:
Eloïse Larnac, Sébastien Méthot, Frédéric Pelchat, Marc-Antoine Millette, Alicia Montoni, Christian Salesse, Valérie Haydont, Laurent Marrot, Patrick J. Rochette
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9146 (2024)
Ultraviolet (UV) exposure and atmospheric pollution are both independently implicated in skin diseases such as cancer and premature aging. UVA wavelengths, which penetrate in the deep layers of the skin dermis, exert their toxicity mainly through chr
Externí odkaz:
https://doaj.org/article/7589113edca3402298f0ce0adf5765fe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Fuchs endothelial corneal dystrophy (FECD) is characterized by an accelerated loss of corneal endothelial cells. Since the function of these cells is to maintain the cornea in a state of deturgescence necessary for its transparency, the depl
Externí odkaz:
https://doaj.org/article/9326b6ab4eb54f6d8b13f63562578596
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1905 (2024)
Light and atmospheric pollution are both independently implicated in cancer induction and premature aging. Evidence has been growing more recently on the toxic synergy between light and pollutants. Polycyclic aromatic hydrocarbons (PAHs) originate fr
Externí odkaz:
https://doaj.org/article/ea375a4f96cf41b59041501626656bca
Autor:
Corinne Zinflou, Patrick J. Rochette
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17385 (2023)
High energy visible (HEV) blue light is an increasing source of concern for visual health. Polycyclic aromatic hydrocarbons (PAH), a group of compounds found in high concentrations in smokers and polluted environments, accumulate in the retinal pigme
Externí odkaz:
https://doaj.org/article/414769af51f644fd88b1c103ebba18b1
Autor:
Marie M Dorr, Patrick J Rochette
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0283572 (2023)
Absorption of ultraviolet radiation (UVR) by DNA leads to the predominant formation of cyclobutane pyrimidine dimers (CPD). Since those CPD are responsible for the driver mutations found in skin cancers, their efficient repair is critical. We previou
Externí odkaz:
https://doaj.org/article/4a6b5f8218f0419e857f367367c14e2a
Autor:
Rodrigo Molina Martins, Silvia de Siqueira Martins, Gustavo Luis Ferreira Barbosa, Maria José Vieira Fonseca, Patrick J. Rochette, Véronique J. Moulin, Luis Alexandre Pedro de Freitas
Publikováno v:
Journal of Microencapsulation. 39:668-679
Solid lipid nanoparticles (SLNs) containing rutin were prepared to enhance their photochemopreventive effect on the skin. SLNs were produced by the hot melt microemulsion technique. Two 3D skin models
Publikováno v:
Photochemistry and Photobiology.
Solar radiation and cigarette smoke are two environmental risk factors known to affect skin integrity. Although the toxic effects of these factors on skin have been widely studied separately, few studies have focused on their interaction. The objecti
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173740 (2017)
Exposure to solar ultraviolet type B (UVB), through the induction of cyclobutane pyrimidine dimer (CPD), is the major risk factor for cutaneous cancer. Cells respond to UV-induced CPD by triggering the DNA damage response (DDR) responsible for signal
Externí odkaz:
https://doaj.org/article/54bfd05a2bf74925a7f6ed7c541efdf5