Zobrazeno 1 - 10
of 146 912
pro vyhledávání: '"Patrick J"'
Autor:
Maria J. Santana, Oyindamola Jaja, Qiuli Duan, Erika D. Penz, Kristin L. Fraser, Patrick J. Hanly, Sachin R. Pendharkar
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract Background Previous research has suggested that alternative (respiratory) care providers (ACP) may provide affordable, accessible care for sleep-disordered breathing (SDB) that decreases wait-times and improves clinical outcomes. The objecti
Externí odkaz:
https://doaj.org/article/2a4da50739da4a429f0b5a76b8cb151b
Autor:
Sebastian T. Tong, Kris Pui Kwan Ma, Ajla Pleho, Brennan Keiser, Chialing Hsu, Dawn M. Ehde, Mary C. Curran, Judith I. Tsui, Patrick J. Raue, Kari A. Stephens
Publikováno v:
Addiction Science & Clinical Practice, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background Patients with chronic pain on opioids frequently experience loneliness, which is associated with poorer health outcomes and higher risk for opioid misuse and opioid use disorder. Given that almost half of opioids are prescribed in
Externí odkaz:
https://doaj.org/article/b7c9abf708b64cd89ad1bed8fb2c0d6e
Publikováno v:
IET Control Theory & Applications, Vol 18, Iss 13, Pp 1710-1728 (2024)
Abstract This paper considers the equilibrium‐free stability and performance analysis of discrete‐time nonlinear systems. Two types of equilibrium‐free notions are considered. Namely, the universal shifted concept, which considers stability and
Externí odkaz:
https://doaj.org/article/5b30a42f2fda45e79c03dd812708cd88
Autor:
Zahraa S. Al-Taie, Simon J. Coles, Aileen Congreve, Dylan Ford, Lucy Green, Peter N. Horton, Leigh F. Jones, Pippa Kett, Rolf Kraehenbuehl, Patrick J. Murphy, Graham J. Tizzard, Niles B. Willmore, Oliver T. Wright
Publikováno v:
Reactions, Vol 5, Iss 3, Pp 567-586 (2024)
N-alkylated C2-symmetric amino acid amide derivatives were shown to catalyse the Michael addition of 2-hydroxy-1,4-napthoquinone to β-nitrostyrene, achieving a maximum ee of 44%. The corresponding trifluoroacetic acid salts also catalysed the aldol
Externí odkaz:
https://doaj.org/article/2e058adf8e1e4961b8135f679ae6da19
Autor:
Ivan Duran, Ankita Banerjee, Patrick J. Flaherty, Yok-Ai Que, Colleen M. Ryan, Laurence G. Rahme, Amy Tsurumi
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Background Multiple organ failure/dysfunction syndrome (MOF/MODS) is a major cause of mortality and morbidity among severe trauma patients. Current clinical practices entail monitoring physiological measurements and applying clinical score s
Externí odkaz:
https://doaj.org/article/b1d2358f051443a1afa40bbecfc74c6c
Autor:
Jaclyn M. W. Hughto, Josiah D. Rich, Patrick J. A. Kelly, Stephanie A. Vento, Joseph Silcox, Madeline Noh, David R. Pletta, Earth Erowid, Fire Erowid, Traci C. Green
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background In recent years, overdoses involving illicit cocaine, methamphetamine, and other stimulants have increased in the U.S. The unintentional consumption of stimulants containing illicit fentanyl is a major risk factor for overdoses, p
Externí odkaz:
https://doaj.org/article/d7da2575573848e4abbfe8db1b912e38
Autor:
Peipei Wang, Melissa D. Lehti-Shiu, Serena Lotreck, Kenia Segura Abá, Patrick J. Krysan, Shin-Han Shiu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The formation of complex traits is the consequence of genotype and activities at multiple molecular levels. However, connecting genotypes and these activities to complex traits remains challenging. Here, we investigate whether integrating ge
Externí odkaz:
https://doaj.org/article/dfaccd8c0e494c988f05fd0ef164293b
Autor:
Hannah C. Bennett, Qingguang Zhang, Yuan-ting Wu, Steffy B. Manjila, Uree Chon, Donghui Shin, Daniel J. Vanselow, Hyun-Jae Pi, Patrick J. Drew, Yongsoo Kim
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Aging is frequently associated with compromised cerebrovasculature and pericytes. However, we do not know how normal aging differentially impacts vascular structure and function in different brain areas. Here we utilize mesoscale microscopy
Externí odkaz:
https://doaj.org/article/109877cae2124134aef4a4db00150a19
Autor:
F. Aaron Cruz-Navarrete, Nicola J. Baxter, Adam J. Flinders, Anamaria Buzoianu, Matthew J. Cliff, Patrick J. Baker, Jonathan P. Waltho
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Metabolic regulation occurs through precise control of enzyme activity. Allomorphy is a post-translational fine control mechanism where the catalytic rate is governed by a conformational switch that shifts the enzyme population between forms
Externí odkaz:
https://doaj.org/article/3a6f90adbcce473198152379b2b8647a
Publikováno v:
Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract Regenerative potential is governed by a complex process of transcriptional reprogramming, involving chromatin reorganization and dynamics in transcription factor binding patterns throughout the genome. The degree to which chromatin and epige
Externí odkaz:
https://doaj.org/article/91bd966c9e0f4dd186dd0f806506d69b