Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Patrick Hauswirth"'
Autor:
Christian Roehrig, Markus Huemer, Dominique Lorgé, Fabienne Arn, Nadine Heinrich, Lavanja Selvakumar, Lynn Gasser, Patrick Hauswirth, Chun-Chi Chang, Tiziano A. Schweizer, Fritz Eichenseher, Steffi Lehmann, Annelies S. Zinkernagel, Mathias Schmelcher
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Bacterial infections are a growing global healthcare concern, as an estimated annual 4.95 million deaths are associated with antimicrobial resistance (AMR). Methicillin-resistant Staphylococcus aureus is one of the deadliest pathogens and a
Externí odkaz:
https://doaj.org/article/49556bdc79fb40e0848bc9a5790f6e34
Autor:
Claudio L. Alter, Pascal Detampel, Roman B. Schefer, Claudia Lotter, Patrick Hauswirth, Ramya D. Puligilla, Vera J. Weibel, Susanne H. Schenk, Wolf Heusermann, Melanie Schürz, Nicole Meisner-Kober, Cornelia Palivan, Tomaž Einfalt, Jörg Huwyler
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Extracellular vesicles (EVs) are highly interesting for the design of next-generation therapeutics. However, their preparation methods face challenges in standardization, yield, and reproducibility. Here, we describe a highly efficient and r
Externí odkaz:
https://doaj.org/article/be10fbb715fc4794919ad22eb4023b74
Autor:
Patrick Hauswirth, Jonas Buck, Ramya Puligilla, Claudio Luca Alter, Sandro Sieber, Beatrice Claudi, Joseph Fanous, Dirk Bumann, Jörg Huwyler
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 5, p 99 (2023)
Introduction: Blood infections from multi-drug-resistant Salmonella pose a major health burden. This is especially true because Salmonella can survive and replicate intracellularly, and the development of new treatment strategies is dependent on expe
Externí odkaz:
https://doaj.org/article/0c7e1f50b348432794061c38b095f880
Autor:
Patrick Hauswirth, Philipp Graber, Katarzyna Buczak, Riccardo Vincenzo Mancuso, Susanne Heidi Schenk, Jürg P. F. Nüesch, Jörg Huwyler
Publikováno v:
Viruses, Vol 15, Iss 1, p 209 (2023)
Oncotoxic proteins such as the non-structural protein 1 (NS1), a constituent of the rodent parvovirus H1 (H1-PV), offer a novel approach for treatment of tumors that are refractory to other treatments. In the present study, mutated NS1 variants were
Externí odkaz:
https://doaj.org/article/381a555128ab48bc97c9cf8e4d23cdea
Autor:
Jörg Huwyler, Dirk Bumann, Joseph Fanous, Beatrice Claudi, Sandro Sieber, Claudio Luca Alter, Ramya Puligilla, Jonas Buck, Patrick Hauswirth
Publikováno v:
Frontiers in Bioscience-Landmark. 28:99
Autor:
Bernhard Englinger, Salvatore Piscuoglio, Jean Rommelaere, Dominik Witzigmann, Sushilla van Schoonhoven, Walter Berger, David Grünig, Xue-Ting Tran, Patrick Hauswirth, Susanne H. Schenk, Stephan Krähenbühl, Jörg Huwyler, Luigi Terracciano, Manuela Lanzafame, Philip Grossen, Cristina Quintavalle, Jürg P. F. Nüesch, Luca Quagliata
Publikováno v:
Journal of Controlled Release. 334:138-152
Hepatocellular carcinoma (HCC) is related to increasing incidence rates and poor clinical outcomes due to lack of efficient treatment options and emerging resistance mechanisms. The aim of the present study is to exploit a non-viral gene therapy enab
Autor:
Stephan Urban, Anna Pratsinis, Philipp Uhl, Dominik Witzigmann, Walter Mier, Susanne H. Schenk, Jörg Huwyler, Patrick Hauswirth, Jan Stephan Bolten
Publikováno v:
Molecular Pharmaceutics. 18:2004-2014
Recently, a lipopeptide derived from the hepatitis B virus (HBV) large surface protein has been developed as an HBV entry inhibitor. This lipopeptide, called MyrcludexB (MyrB), selectively binds to the sodium taurocholate cotransporting polypeptide (