Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Patrick Han"'
Publikováno v:
BMC Neuroscience, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Background Myelin oligodendrocyte glycoprotein-associated disorders (MOGAD) is an autoimmune central nervous system disease. Antigen-specific immune tolerance using nanoparticles such as Polylactic-co-glycolic acid (PLGA) have recently been
Externí odkaz:
https://doaj.org/article/87397938ade640c280fbf50edec49bae
Autor:
Joanna B Pawlak, Jack Chun-Chieh Hsu, Hongjie Xia, Patrick Han, Hee-Won Suh, Tyler L Grove, Juliet Morrison, Pei-Yong Shi, Peter Cresswell, Maudry Laurent-Rolle
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011286 (2023)
Flaviviruses continue to emerge as global health threats. There are currently no Food and Drug Administration (FDA) approved antiviral treatments for flaviviral infections. Therefore, there is a pressing need to identify host and viral factors that c
Externí odkaz:
https://doaj.org/article/4b0c2f150fa74a3386313ece1cbb0c9c
Publikováno v:
International Journal of Strategic Property Management, Vol 25, Iss 4, Pp 254-266 (2021)
This study explicitly rejects the prima facie proposition that the top-tier investment banks are capable of delivering supernormal value creation to the shareholders of a REIT acquirer in a corporate acquisition. Using the event study method, we find
Externí odkaz:
https://doaj.org/article/eca51fd0bfad4bdca12bf5d4471f8e3a
Autor:
Ayesha B. Alvero, Douglas Hanlon, Mary Pitruzzello, Renata Filler, Eve Robinson, Olga Sobolev, Roslyn Tedja, Alessandra Ventura, Marcus Bosenberg, Patrick Han, Richard L. Edelson, Gil Mor
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Ovarian cancer accounts for most deaths from gynecologic malignancies. Although more than 80% of patients respond to first-line standard of care, most of these responders present with recurrence and eventually succumb to carcinomatosis and chemothera
Externí odkaz:
https://doaj.org/article/9887764f3ef24c5c98a8fced536f8082
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Molecular self-assembly is controlled by chemical and entropic factors, but theory has not been able to differentiate the role of each. Here, the authors unambiguously address this question for self-assembly on metal surfaces, using a new computation
Externí odkaz:
https://doaj.org/article/565d824c16234efa8fdba44e3b51cb27
Publikováno v:
Royal Society Open Science, Vol 3, Iss 7 (2016)
Direct simulation of a model with a large state space will generate enormous volumes of data, much of which is not relevant to the questions under study. In this paper, we consider a molecular self-assembly model as a typical example of a large state
Externí odkaz:
https://doaj.org/article/5253d5c8944c41239461cacaff4d56cb
Autor:
Michael D McHugh, Tarek M. Fahmy, Sean Bickerton, Jung Seok Lee, Ragy Ragheb, Rabib Chaudhury, David A. Horwitz, Shihan N. Khan, Alyssa Siefert, Robert M. Samstein, Karlo Perica, José M. Carballido, Gerald Rea, Dongin Kim, Hyun Bong Park, Jason M. Criscione, Patrick Han
Publikováno v:
Nature Biomedical Engineering. 5:983-997
Oral formulations of insulin are typically designed to improve its intestinal absorption and increase its blood bioavailability. Here we show that polymerized ursodeoxycholic acid, selected from a panel of bile-acid polymers and formulated into nanop
Autor:
Hemalatha Kanakarajan, Wouter De Baene, Karin Gehring, Daniëlle B. P. Eekers, Patrick Hanssens, Margriet Sitskoorn
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background Enhancing Local Control (LC) of brain metastases is pivotal for improving overall survival, which makes the prediction of local treatment failure a crucial aspect of treatment planning. Understanding the factors that influence LC
Externí odkaz:
https://doaj.org/article/20d6cad0c21e42758e61761f6eee3c8a
Publikováno v:
Bioconjugate Chemistry. 31:2541-2552
Exosomes have been widely demonstrated as an effective anticancer therapeutic moiety. However, their clinical translation has been limited by the requirement of prohibitively high therapeutic doses due to their lack of specificity in delivery and, co
Autor:
Tarek M. Fahmy, Shari Yosinski, Rabib Chaudhury, Mark A. Reed, Zachary Kobos, Jung Seok Lee, Patrick Han
Publikováno v:
ACS Nano. 14:8646-8657
The sensitivity and speed with which the immune system reacts to host disruption is unrivaled by any detection method for pathogenic biomarkers or infectious signatures. Engagement of cellular immunity in response to infections or cancer is contingen