Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Patrick Hamilton"'
Autor:
Dharshi Karalapillai, Laurence Weinberg, Ary Serpa Neto, Philip J. Peyton, Louise Ellard, Raymond Hu, Brett Pearce, Chong O. Tan, David Story, Mark O’Donnell, Patrick Hamilton, Chad Oughton, Jonathan Galtieri, Anthony Wilson, Grace Liskaser, Ajay Balasubramaniam, Glenn Eastwood, Rinaldo Bellomo, Daryl A. Jones
Publikováno v:
BMC Anesthesiology, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background We recently reported the results for a large randomized controlled trial of low tidal volume ventilation (LTVV) versus conventional tidal volume (CTVV) during major surgery when positive end expiratory pressure (PEEP) was equal be
Externí odkaz:
https://doaj.org/article/92f11032c9e84138be40ceee99775576
Autor:
Dharshi Karalapillai, Laurence Weinberg, Ary Serpa Neto, Philip J. Peyton, Louise Ellard, Raymond Hu, Brett Pearce, Chong Tan, David Story, Mark O’Donnell, Patrick Hamilton, Chad Oughton, Jonathan Galtieri, Sree Appu, Anthony Wilson, Glenn Eastwood, Rinaldo Bellomo, Daryl A. Jones
Publikováno v:
BMC Anesthesiology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Low tidal volume (VT) ventilation and its associated increase in arterial carbon dioxide (PaCO2) may affect postoperative neurologic function. We aimed to test the hypothesis that intraoperative low VT ventilation affect the incid
Externí odkaz:
https://doaj.org/article/030986c63abb4516abe43296236207e5
Autor:
Patrick Hamilton, Kieran Blaikie, Stephen A Roberts, Matthew Gittins, Mallory L Downie, Sanjana Gupta, Catalin Voinescu, Durga Kanigicherla, Horia Stanescu, Robert Kleta, Paul Brenchley
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0281795 (2023)
BackgroundDespite MN being one of the most common causes of nephrotic syndrome worldwide, its biological and environmental determinants are poorly understood in large-part due to it being a rare disease. Making use of the UK Biobank, a unique resourc
Externí odkaz:
https://doaj.org/article/4f56f781985d4549bd09452989ed66ef
Autor:
Omar Ragy, Vilma Rautemaa, Alison Smith, Paul Brenchley, Durga Kanigicherla, Patrick Hamilton
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281726 (2023)
BackgroundSince the emergence of the anti-PLA2R antibody (PLA2R-Ab) test, nephrology practice has not changed dramatically, with most nephrologists still relying on a kidney biopsy to diagnose membranous nephropathy. In this study, we examined the cl
Externí odkaz:
https://doaj.org/article/41c1ffb9dbee471ba1e612ea2955ce07
Autor:
Kathrine Parker, Patrick Hamilton, Prasanna Hanumapura, Laveena Castelino, Michelle Murphy, Rachael Challiner, Jecko Thachil, Leonard Ebah
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background Coronavirus-19 (COVID-19) has been declared a global pandemic by the World Health Organisation. Severe disease typically presents with respiratory failure but Acute Kidney Injury (AKI) and a hypercoagulable state can also occur. E
Externí odkaz:
https://doaj.org/article/aabd2dfd1ec84e33835fe3828ba5fe93
Autor:
Marcus Lowe, Antony Payton, Arpana Verma, Judith Worthington, Isla Gemmell, Patrick Hamilton, William Ollier, Titus Augustine, Kay Poulton
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Human leukocyte antigens (HLA) have been associated with renal function, but previous studies report contradictory findings with little consensus on the exact nature or impact of this observation. This study included 401,307 white British su
Externí odkaz:
https://doaj.org/article/9e4bec67b54e4d8488a8d21324532617
Autor:
Omar Ragy, Patrick Hamilton, Anjali Pathi, Adil Abdalla Mohamed Ahmed, Sandip Mitra, Durga A.K. Kanigicherla
Publikováno v:
Glomerular Diseases, Pp 1-1 (2023)
Introduction and Aims Therapy of Primary Membranous nephropathy (PMN) with progressive advanced kidney dysfunction is challenging with limited literature and no clear therapeutic strategies. This is due to the scant evidence of effectiveness and unce
Externí odkaz:
https://doaj.org/article/e2cecc2947734e8cbbf5e49914bfeeef
Autor:
Jingyuan Xie, Lili Liu, Nikol Mladkova, Yifu Li, Hong Ren, Weiming Wang, Zhao Cui, Li Lin, Xiaofan Hu, Xialian Yu, Jing Xu, Gang Liu, Yasar Caliskan, Carlo Sidore, Olivia Balderes, Raphael J. Rosen, Monica Bodria, Francesca Zanoni, Jun Y. Zhang, Priya Krithivasan, Karla Mehl, Maddalena Marasa, Atlas Khan, Fatih Ozay, Pietro A. Canetta, Andrew S. Bomback, Gerald B. Appel, Simone Sanna-Cherchi, Matthew G. Sampson, Laura H. Mariani, Agnieszka Perkowska-Ptasinska, Magdalena Durlik, Krzysztof Mucha, Barbara Moszczuk, Bartosz Foroncewicz, Leszek Pączek, Ireneusz Habura, Elisabet Ars, Jose Ballarin, Laila-Yasmin Mani, Bruno Vogt, Savas Ozturk, Abdülmecit Yildiz, Nurhan Seyahi, Hakki Arikan, Mehmet Koc, Taner Basturk, Gonca Karahan, Sebahat Usta Akgul, Mehmet Sukru Sever, Dan Zhang, Domenico Santoro, Mario Bonomini, Francesco Londrino, Loreto Gesualdo, Jana Reiterova, Vladimir Tesar, Claudia Izzi, Silvana Savoldi, Donatella Spotti, Carmelita Marcantoni, Piergiorgio Messa, Marco Galliani, Dario Roccatello, Simona Granata, Gianluigi Zaza, Francesca Lugani, GianMarco Ghiggeri, Isabella Pisani, Landino Allegri, Ben Sprangers, Jin-Ho Park, BeLong Cho, Yon Su Kim, Dong Ki Kim, Hitoshi Suzuki, Antonio Amoroso, Daniel C. Cattran, Fernando C. Fervenza, Antonello Pani, Patrick Hamilton, Shelly Harris, Sanjana Gupta, Chris Cheshire, Stephanie Dufek, Naomi Issler, Ruth J. Pepper, John Connolly, Stephen Powis, Detlef Bockenhauer, Horia C. Stanescu, Neil Ashman, Ruth J. F. Loos, Eimear E. Kenny, Matthias Wuttke, Kai-Uwe Eckardt, Anna Köttgen, Julia M. Hofstra, Marieke J. H. Coenen, Lambertus A. Kiemeney, Shreeram Akilesh, Matthias Kretzler, Lawrence H. Beck, Benedicte Stengel, Hanna Debiec, Pierre Ronco, Jack F. M. Wetzels, Magdalena Zoledziewska, Francesco Cucca, Iuliana Ionita-Laza, Hajeong Lee, Elion Hoxha, Rolf A. K. Stahl, Paul Brenchley, Francesco Scolari, Ming-hui Zhao, Ali G. Gharavi, Robert Kleta, Nan Chen, Krzysztof Kiryluk
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Membranous nephropathy (MN) is a rare autoimmune disease of podocyte-directed antibodies, such as anti-phospholipase A2 receptor. Here, the authors report a genome-wide association study for MN and identify two previously unreported loci encompassing
Externí odkaz:
https://doaj.org/article/673c37d7cf9b414b91486e389bd81da8
Autor:
Patrick Hamilton, Prasanna Hanumapura, Laveena Castelino, Robert Henney, Kathrine Parker, Mukesh Kumar, Michelle Murphy, Tamer Al-Sayed, Sarah Pinnington, Tim Felton, Rachael Challiner, Leonard Ebah
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241544 (2020)
IntroductionCOVID-19 has spread globally to now be considered a pandemic by the World Health Organisation. Initially patients appeared to have a respiratory limited disease but there are now increasing reports of multiple organ involvement including
Externí odkaz:
https://doaj.org/article/f7d4fc95e1d54a61a79c29901c75ee9c
Autor:
Peter S Hall, Elizabeth D Mitchell, Alison F Smith, David A Cairns, Michael Messenger, Michelle Hutchinson, Judy Wright, Karen Vinall-Collier, Claire Corps, Patrick Hamilton, David Meads, Andrew Lewington
Publikováno v:
Health Technology Assessment, Vol 22, Iss 32 (2018)
Background: Acute kidney injury (AKI) is highly prevalent in hospital inpatient populations, leading to significant mortality and morbidity, reduced quality of life and high short- and long-term health-care costs for the NHS. New diagnostic tests may
Externí odkaz:
https://doaj.org/article/ad4b910541ef4316b0083230bbffb35c