Corrigendum: Selective Histone Deacetylase Inhibitor ACY-241 (Citarinostat) Plus Nivolumab in Advanced Non-Small Cell Lung Cancer: Results From a Phase Ib Study

Autor: Mark M. Awad, Yvan Le Bruchec, Brian Lu, Jason Ye, Julie Ann Miller, Patrick H. Lizotte, Megan E. Cavanaugh, Amanda J. Rode, Calin Dan Dumitru, Alexander Spira

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Externí odkaz: https://doaj.org/article/3963600921ff4ed4ab2f25dbc17d9408

Pre-T cell receptor self-MHC sampling restricts thymocyte dedifferentiation

Autor: Jonathan S. Duke-Cohan, Aoi Akitsu, Robert J. Mallis, Cameron M. Messier, Patrick H. Lizotte, Jon C. Aster, Wonmuk Hwang, Matthew J. Lang, Ellis L. Reinherz

Publikováno v: Nature

Programming T lymphocytes to distinguish self from non-self is a vital, multi-step process arising in the thymus(1–4). Signalling through the pre-T cell receptor (preTCR), a CD3-associated heterodimer comprising an invariant pTα chain and a clone-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7892b18e723adaf83475c6a15162d7
https://doi.org/10.1038/s41586-022-05555-7

Data from Activation of Tumor-Cell STING Primes NK-Cell Therapy

Autor: David A. Barbie, Raphael Bueno, Cloud P. Paweletz, Rizwan Romee, Michael Y. Tolstorukov, Juan J. Miret, Pasi A. Jänne, Eric L. Smith, Neil Lineberry, Alexander Parent, Richard C. Gregory, Vicky A. Appleman, Adnan O. Abu-Yousif, William G. Richards, Assunta De Rienzo, Marina Vivero, Israel Cañadas, Ze-Hua Li, Pinar O. Eser, Antja-Voy Hartley, Thomas P. Albertson, Timothy J. Haggerty, Kartika Venugopal, Corinne E. Gustafson, Tran C. Thai, Saemi Han, Arrien A. Bertram, Minh Ha, Ha V. Vo, Ari Zlota, Anna M. Lee-Hassett, Pieter J. Schol, Tetsuo Tani, Navin R. Mahadevan, Erin Shannon, Cameron M. Messier, Bonje Obua, Nathaniel Spicer, Brandon Piel, Minyue Chen, Brittany Meisenheimer, Moataz Noureddine, Ismail Ozgenc, Matthew A. Booker, Patrick H. Lizotte, Marco Campisi, Mubin Tarannum, Elena V. Ivanova, Erik H. Knelson

Activation of the stimulator of interferon genes (STING) pathway promotes antitumor immunity but STING agonists have yet to achieve clinical success. Increased understanding of the mechanism of action of STING agonists in human tumors is key to devel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34335b05bd2da45a66fc885095d546f7
https://doi.org/10.1158/2326-6066.c.6550907

Supplementary Data from Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

Autor: David A. Barbie, Cloud Peter Paweletz, David Dornan, Kwok-Kin Wong, Genevieve M. Boland, Roger D. Kamm, Keith T. Flaherty, F. Stephen Hodi, Patrick A. Ott, Jochen H. Lorch, Paul T. Kirschmeier, Gordon J. Freeman, Eliezer M. Van Allen, Levi A. Garraway, Meenhard Herlyn, Juan Miret, Charles H. Yoon, Raphael Bueno, William G. Richards, Joshua Wong, Vivek Sivathanu, Thanh U. Barbie, Benchun Miao, Rohit Thummalapalli, Shunsuke Kitajima, Brian C. Miller, James M. Cleary, Sareh Parangi, Viswanath Gunda, Guilherme Rabinowits, Nicole R. LeBoeuf, Manisha Thakuria, Benjamin Izar, Parin Shah, Mei-Ju Su, Lisa Cameron, Anat O. Stemmer-Rachamimov, Jean-Pierre Eliane, Adriano Piris, Mai P. Hoang, Wei Huang, Glenn J. Hanna, Shuai Li, Hua Zhang, Eric S. Wang, Raven Vlahos, Marc R. Hammond, Tran C. Thai, Israel Cañadas, Michal Barzily-Rokni, Zhiheng Jia, Lance Stapleton, Maria Anguiano, Lauren Keogh, Robert E. Jones, Asaf Rotem, Alicia Smart, Bart Phillips, Prafulla C. Gokhale, Andrew Portell, Joshua A. Kaplan, Chandrasekar Venkataramani, Max Quinn, Ashley Merlino, Jong Wook Kim, Hans Vitzthum, Mark Bittinger, Sangeetha Palakurthi, Zhi Wei, Chaoran Cheng, Tian Tian, Gao Zhang, William Walker, Meng Xiao He, Diana Miao, Hongye Liu, Jiehui Deng, Michaela Bowden, Chensheng W. Zhou, Susanna Stinson, Elena Ivanova, Patrick H. Lizotte, Amir R. Aref, Russell W. Jenkins

Supplementary Figure Legends and Figures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2e4f5e724ad7a5b7c5e1c4faeafecb
https://doi.org/10.1158/2159-8290.22531831.v1

Supp. Movie 2 from Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids

Autor: David A. Barbie, Cloud Peter Paweletz, David Dornan, Kwok-Kin Wong, Genevieve M. Boland, Roger D. Kamm, Keith T. Flaherty, F. Stephen Hodi, Patrick A. Ott, Jochen H. Lorch, Paul T. Kirschmeier, Gordon J. Freeman, Eliezer M. Van Allen, Levi A. Garraway, Meenhard Herlyn, Juan Miret, Charles H. Yoon, Raphael Bueno, William G. Richards, Joshua Wong, Vivek Sivathanu, Thanh U. Barbie, Benchun Miao, Rohit Thummalapalli, Shunsuke Kitajima, Brian C. Miller, James M. Cleary, Sareh Parangi, Viswanath Gunda, Guilherme Rabinowits, Nicole R. LeBoeuf, Manisha Thakuria, Benjamin Izar, Parin Shah, Mei-Ju Su, Lisa Cameron, Anat O. Stemmer-Rachamimov, Jean-Pierre Eliane, Adriano Piris, Mai P. Hoang, Wei Huang, Glenn J. Hanna, Shuai Li, Hua Zhang, Eric S. Wang, Raven Vlahos, Marc R. Hammond, Tran C. Thai, Israel Cañadas, Michal Barzily-Rokni, Zhiheng Jia, Lance Stapleton, Maria Anguiano, Lauren Keogh, Robert E. Jones, Asaf Rotem, Alicia Smart, Bart Phillips, Prafulla C. Gokhale, Andrew Portell, Joshua A. Kaplan, Chandrasekar Venkataramani, Max Quinn, Ashley Merlino, Jong Wook Kim, Hans Vitzthum, Mark Bittinger, Sangeetha Palakurthi, Zhi Wei, Chaoran Cheng, Tian Tian, Gao Zhang, William Walker, Meng Xiao He, Diana Miao, Hongye Liu, Jiehui Deng, Michaela Bowden, Chensheng W. Zhou, Susanna Stinson, Elena Ivanova, Patrick H. Lizotte, Amir R. Aref, Russell W. Jenkins

PDOTS Movie 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5816e3f89be3fcf42e03c4886a26bb
https://doi.org/10.1158/2159-8290.22531837.v1