Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Patrick Gubser"'
Autor:
Gunhild Unterstab, Renato Paro, Marco Geigges, Christoph Hess, Patrick Gubser, Yannic Lecoultre
Publikováno v:
Scientific Reports, 10 (1)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Reverse-transcription quantitative real-time polymerase chain reaction (RT-qPCR) is widely used for mRNA quantification. To accurately measure changing gene transcript levels under different experimental conditions, the use of appropriate reference g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c87d84d6c81a1682da3b24f213df73
https://www.repository.cam.ac.uk/handle/1810/307055
https://www.repository.cam.ac.uk/handle/1810/307055
Autor:
Marco Fischer, Gunhild Unterstab, Jasmin Grählert, Ursula Sauder, Rebekah Steiner, Glenn R. Bantug, Christoph Hess, Patrick Gubser, Gideon Hoenger, Leyla Develioglu, Anne-Valérie Burgener, Sarah Dimeloe, Maria L. Balmer
Publikováno v:
European Journal of Immunology. 48:1632-1643
The role of mitochondrial biogenesis during naive to effector differentiation of CD8+ T cells remains ill explored. In this study, we describe a critical role for early mitochondrial biogenesis in supporting cytokine production of nascent activated h
Autor:
Patrick Gubser, Corina Frick, Sarah Dimeloe, Yannic Lecoultre, Alfred Zippelius, Anja Langenkamp, Glenn R. Bantug, Leyla Develioglu, Daniela S. Thommen, Jordan Loeliger, Marco Fischer, Christoph Hess, Florian Marquardsen
Publikováno v:
Science signaling. 12(599)
Transforming growth factor-β (TGF-β) is produced by tumors, and increased amounts of this cytokine in the tumor microenvironment and serum are associated with poor patient survival. TGF-β-mediated suppression of antitumor T cell responses contribu
Autor:
Patrick Gubser, Leyla Razik, Glenn R. Bantug, Sarah Dimeloe, Anja Langenkamp, Morgane Ravon, Marco Fischer, Corina Frick, Christoph Hess
Publikováno v:
European Journal of Immunology. 44:3614-3620
ATP-binding cassette (ABC) transporters, including ABC-transporter B1 (ABCB1), extrude drugs, metabolites, and other compounds (such as mitotracker green (MTG)) from cells. Susceptibility of CD4(+) regulatory T (Treg) cells to the ABCB1-substrate cyc
Autor:
Patrick Gubser, Jörg Sigle, Martin Stern, Andreas Buser, Olivier Gasser, Christoph Hess, Hans H. Hirsch, Bojana Durovic
Epstein-Barr virus (EBV) infects ∼95% of the adult population. The factors that confer protection in the remaining ∼5% remain unknown. In an exploratory study, we assessed immunogenetic factors and tonsillectomy in a cohort of 17 EBV-negative and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0920b30541f7d76193cce6836694811c
https://europepmc.org/articles/PMC3648112/
https://europepmc.org/articles/PMC3648112/
Autor:
Leyla Razik, Sarah Dimeloe, Marco Fischer, Glenn R. Bantug, Christoph Hess, Gideon Hoenger, Patrick Gubser, Annaïse Jauch, Bojana Durovic
Publikováno v:
Nature Immunology
Antigen-experienced memory T cells acquire effector function with innate-like kinetics; however, the metabolic requirements of these cells are unknown. Here we show that rapid interferon-γ (IFN-γ) production of effector memory (EM) CD8(+) T cells,
Autor:
Friederike Kesten, Katharina Glatz, Markus Aschwanden, Thomas Daikeler, Patrick Gubser, Christoph Hess
Publikováno v:
Swiss Medical Weekly.
Giant cell arteritis (GCA) is the most common of the vasculitis syndromes and, being a disease of the elderly, its incidence is increasing with the general ageing of the population. GCA is most feared for its early complications, namely blindness and
Autor:
Andrea Steinhuber, Petra S. Eisele, Christoph Handschin, Gabriela Zenhaeusern, Patrick Gubser, Andrej Trampuz, Andrew D. Luster, Olivier Gasser, Christoph Hess
T cells move randomly (“random-walk”), a characteristic thought to be integral to their function. Using migration assays and time-lapse microscopy, we found that CD8+ T cells lacking the lymph node homing receptors CCR7 and CD62L migrate more eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24da26250df993615730db485a609b18
https://edoc.unibas.ch/5035/
https://edoc.unibas.ch/5035/
Autor:
Ludwig Kappos, Patrick Gubser, Andrew D. Luster, Anne-Valérie Burgener, Volker Brinkmann, Christoph Hess, Matthias Mehling
Publikováno v:
Journal of Allergy and Clinical Immunology. 131:1440-1443.e7