Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Patrick Grailhe"'
Autor:
Stephane Illiano, Bruno Poirier, Claire Minoletti, Olivier Pasquier, Laurence Riva, Xavier Chenede, Isabelle Menguy, Michel Guillotel, Philippe Prigent, Stéphane Le Claire, Florence Gillot, Gilbert Thill, François Lo Presti, Alain Corbier, Jean-Christophe Le Bail, Patrick Grailhe, Edith Monteagudo, Raffaele Ingenito, Elisabetta Bianchi, Christophe Philippo, Olivier Duclos, Sergio Mallart, Ross Bathgate, Philip Janiak
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Despite beneficial effects in acute heart failure, the full therapeutic potential of recombinant relaxin-2 has been hampered by its short half-life and the need for intravenous administration limiting its use to intensive care units. A multi
Externí odkaz:
https://doaj.org/article/9680bc4f067244f5859525deb060514b
Publikováno v:
FEBS Open Bio, Vol 10, Iss 10, Pp 2010-2020 (2020)
Sphingosine‐1 phosphate receptor‐1 (S1P1) activation maintains endothelial barrier integrity, whereas S1P1 desensitization induces peripheral blood lymphopenia. The latter is exploited in the approval and/or late‐stage development of receptor
Externí odkaz:
https://doaj.org/article/e022a51d0677491c9f42e7504f1fb2ef
Publikováno v:
FEBS Open Bio, Vol 10, Iss 10, Pp 2010-2020 (2020)
Sphingosine-1 phosphate receptor-1 (S1P1 ) activation maintains endothelial barrier integrity, whereas S1P1 desensitization induces peripheral blood lymphopenia. The latter is exploited in the approval and/or late-stage development of receptor-desens
Autor:
Bruno, Poirier, Veronique, Briand, Dieter, Kadereit, Matthias, Schäfer, Paulus, Wohlfart, Marie-Claire, Philippo, Dominique, Caillaud, Laurent, Gouraud, Patrick, Grailhe, Jean-Pierre, Bidouard, Marc, Trellu, Anthony J, Muslin, Philip, Janiak, Ashfaq A, Parkar
Publikováno v:
Science signaling. 13(634)
Endothelial dysfunction is a hallmark of tissue injury and is believed to initiate the development of vascular diseases. Sphingosine-1 phosphate receptor-1 (S1P
Autor:
Philip Janiak, Dieter Kadereit, Marie-Claire Philippo, Laurent Gouraud, Anthony J. Muslin, Dominique Caillaud, Paulus Wohlfart, Jean-Pierre Bidouard, Véronique Briand, Bruno Poirier, Ashfaq Parkar, Marc Trellu, Patrick Grailhe, Matthias Schäfer
Publikováno v:
Science Signaling. 13
Endothelial dysfunction is a hallmark of tissue injury and is believed to initiate the development of vascular diseases. Sphingosine-1 phosphate receptor-1 (S1P1) plays fundamental physiological roles in endothelial function and lymphocyte homing. Cu
Publikováno v:
European journal of biochemistry. 219(3)
It is well established that tissue-type plasminogen activator (t-PA) binds to the D region of fibrin(ogen) and that two distinct CNBr fragments of fibrinogen (FCB), FCB-2 and FCB-5, comprising parts of this region, stimulate plasminogen activation by