Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Patrick G. K. Mayer"'
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 6, Pp 1427-1445 (2019)
Externí odkaz:
https://doaj.org/article/b2df231c5db7440cb7b83b260ac40900
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 6, Pp 1427-1445 (2019)
Background/aims Hydrophobic bile salts, such as glycochenodeoxycholate (GCDC) can trigger hepatocyte apoptosis, which is prevented by tauroursodesoxycholate (TUDC), but the effects of GCDC and TUDC on sinusoidal bile salt uptake via the Na⁺-tauroch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e1de0af096b542744283e1f9da5375
https://pubmed.ncbi.nlm.nih.gov/31088037
https://pubmed.ncbi.nlm.nih.gov/31088037
Publikováno v:
Zeitschrift für Gastroenterologie. 53
In perfused rat liver, hepatocyte shrinkage induces a Fyn-dependent retrieval of the bile salt export pump (Bsep) and multidrug resistance-associated protein 2 (Mrp2) from the canalicular membrane (Cantore, M., Reinehr, R., Sommerfeld, A., Becker, M.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226096bd7009ab65ac150ad0742f3726
https://doi.org/10.1055/s-0035-1568046
https://doi.org/10.1055/s-0035-1568046
Publikováno v:
European Journal of Medical Research
The hydrophilic bile acid ursodeoxycholic acid (UDCA), which in vivo is converted to its taurine conjugate tauroursodeoxycholic acid (TUDC), is a mainstay in the treatment of cholestatic liver disease. TUDC prevents bile acid-induced cholestasis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3f60d8a63f2338a0057d20d854d1b0