Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Patrick F.M. Meeus"'
Autor:
Tom L. McTier, Adam Schoell, Tara Bidgood, Joyce Login, Aleah Pullins, Patrick F.M. Meeus, Gregory A. Inskeep, Genevieve Gagnon, Huihao Fan
Publikováno v:
Parasites & Vectors, Vol 10, Iss S2, Pp 47-52 (2017)
Parasites & Vectors
Parasites & Vectors
Background Emerging resistance of heartworms (Dirofilaria immitis) to macrocyclic lactone (ML) preventives is an increasing concern for veterinarians, pet owners and animal health companies that supply heartworm preventives, with recent reports of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff5944f36bf98084fda4adb075325d2
http://link.springer.com/article/10.1186/s13071-017-2430-z
http://link.springer.com/article/10.1186/s13071-017-2430-z
Publikováno v:
Journal of Veterinary Internal Medicine
Background Leptospirosis in dogs is a disease of global importance. Early detection and appropriate therapeutic intervention are necessary to resolve infection and prevent zoonotic transmission. However, its diagnosis is hindered by nonspecific clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debfc5fd9371fb27fbb7706cefaa2357
http://europepmc.org/articles/PMC5787205
http://europepmc.org/articles/PMC5787205
Autor:
Erich W. Zinser, William Howson, Tom L. McTier, Tim Stuk, Goodwin Richard M, Patrick F.M. Meeus, Michael P. Curtis, Jason Koch, Jeffrey Ellis Price, Vaillancourt Valerie A, Sanjay Menon, Aleah Pullins, Debra J. Woods, Nathan Anthony Logan Chubb, Laura Hedges
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:1831-1835
Over the last decade, the isoxazoline motif has become the intense focus of crop protection and animal health companies in their search for novel pesticides and ectoparasiticides. Herein we report the discovery of sarolaner, a proprietary, optimized-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860dc9ac80dda49d88ef5693e01c4884
https://doi.org/10.1016/j.bmcl.2016.02.027
https://doi.org/10.1016/j.bmcl.2016.02.027
Publikováno v:
Journal of Feline Medicine and Surgery Open Reports, Vol 4 (2017)
JFMS Open Reports
JFMS Open Reports
Objectives The objective of this study was to compare the diagnostic sensitivities and specificities of WITNESS FeLV-FIV (Zoetis) and SNAP FIV/FeLV Combo Test (IDEXX) for the detection of FeLV p27 antigen in the sera of experimentally feline leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0182862b6ea31281f27f14a6acc93d41
https://doaj.org/article/52cde19be67c4c4ea92f90d8ad1ba7bf
https://doaj.org/article/52cde19be67c4c4ea92f90d8ad1ba7bf
Autor:
Christopher S. Knauer, Gregory A. Inskeep, Laura Hedges, Debra J. Woods, Sanjay Menon, Nathan Anthony Logan Chubb, Tom L. McTier, Michael P. Curtis, Erich W. Zinser, Aleah Pullins, Brian Mills, Patrick F.M. Meeus
Publikováno v:
Veterinary parasitology. 222
The novel isoxazoline ectoparasiticide, sarolaner, was identified during a lead optimization program for an orally-active compound with efficacy against fleas and ticks on dogs. The aim of the discovery program was to identify a novel isoxazoline spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f994d89eca397a808f7377aeda4fba
https://pubmed.ncbi.nlm.nih.gov/26961590
https://pubmed.ncbi.nlm.nih.gov/26961590
Autor:
Hollis N. Erb, Alicia Rollins, David Garcia-Tapia, Bettina Wagner, Christopher G. Earnhart, Richard T. Marconi, Patrick F.M. Meeus, Heather Freer
Lyme disease in the United States is caused byBorrelia burgdorferisensu stricto, which is transmitted to mammals by infected ticks.Borreliaspirochetes differentially express immunogenic outer surface proteins (Osp). Our aim was to evaluate antibody r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9349b4ac195709c2304c8c787d0266b4
https://europepmc.org/articles/PMC3318275/
https://europepmc.org/articles/PMC3318275/
Publikováno v:
Future medicinal chemistry. 3(7)
Despite investment in programs to manage the development of resistance to existing agents, this continues to drive the need for discovery of novel antiparasitic agents for veterinary medicine. Historically, antiparasitic drug discovery was driven by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4268733107a9483d6eca99660ad50291
https://pubmed.ncbi.nlm.nih.gov/21644834
https://pubmed.ncbi.nlm.nih.gov/21644834