Výsledky vyhledávání - "Patrick F Kelly"

Olutasidenib (FT-2102) in patients with relapsed or refractory IDH1-mutant glioma: A multicenter, open-label, phase Ib/II trial

Autor: Macarena I de la Fuente, Howard Colman, Mark Rosenthal, Brian A Van Tine, Danijela Levacic, Tobias Walbert, Hui K Gan, Maria Vieito, Mohammed M Milhem, Kathryn Lipford, Sanjeev Forsyth, Sylvie M Guichard, Yelena Mikhailov, Alexander Sedkov, Julie Brevard, Patrick F Kelly, Hesham Mohamed, Varun Monga

Publikováno v: Scientia

Background Olutasidenib (FT-2102) is a highly potent, orally bioavailable, brain-penetrant and selective inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). The aim of the study was to determine the safety and clinical activity of olutasidenib in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b253bb132081b03fc3679216acf7f5
https://doi.org/10.1093/neuonc/noac139

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Olutasidenib (FT-2102) in patients with relapsed or refractory IDH1-mutant glioma: a multicenter, open-label, phase 1b/2 trial

Autor: Macarena I, de la Fuente, Howard, Colman, Mark, Rosenthal, Brian A, Van Tine, Danijela, Levacic, Tobias, Walbert, Hui K, Gan, Maria, Vieito, Mohammed M, Milhem, Kathryn, Lipford, Sanjeev, Forsyth, Sylvie M, Guichard, Yelena, Mikhailov, Alexander, Sedkov, Julie, Brevard, Patrick F, Kelly, Hesham, Mohamed, Varun, Monga

Publikováno v: Neuro-oncology.

Olutasidenib (FT2102) is a highly potent, orally bioavailable, brain-penetrant and selective inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). The aim of the study was to determine the safety and clinical activity of olutasidenib in patients wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::32e6ebd70c69fd59005b777face6583f
https://pubmed.ncbi.nlm.nih.gov/35639513

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Author response for 'Inhibition of fatty acid synthase with FT ‐4101 safely reduces hepatic de novo lipogenesis and steatosis in obese subjects with NAFLD non‐alcoholic fatty liver disease: results from two early phase randomized trials'

Autor: null Carine Beysen, null Patricia Schroeder, null Eric Wu, null Julie Brevard, null Maria Ribadeneira, null Wei Lu, null Kiran Dole, null Terry E O’Reilly, null Linda Morrow, null Marcus Hompesch, null Marc K Hellerstein, null Kelvin Li, null Lars Johansson, null Patrick F Kelly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4ec277a15895b68e1ce98f7b6c960134
https://doi.org/10.1111/dom.14272/v2/response1

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Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein

Autor: Patrick F. Kelly, Jody Vandergriff, Amit Nathwani, Arthur W. Nienhuis, Elio F. Vanin

Publikováno v: Blood. 96:1206-1214

Limited expression of the amphotropic envelope receptor is a recognized barrier to efficient oncoretroviral vector–mediated gene transfer. Human hematopoietic cell lines and cord blood–derived CD34+ and CD34+, CD38− cell populations and the pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6fc8d722b6f42b10a662139458c491df
https://doi.org/10.1182/blood.v96.4.1206.h8001206_1206_1214

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Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD34+ cells

Autor: Sebastian, Brenner, Narda L, Whiting-Theobald, Gilda F, Linton, Kevin L, Holmes, Mindy, Anderson-Cohen, Patrick F, Kelly, Elio F, Vanin, André M, Pilon, David M, Bodine, Mitchell E, Horwitz, Harry L, Malech

Publikováno v: Blood. 102(8)

In previous studies amphotropic MFGS-gp91phox (murine onco-retrovirus vector) was used in a clinical trial of X-linked chronic granulomatous disease (X-CGD) gene therapy to achieve transient correction of oxidase activity in 0.1% of neutrophils. We l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bb1f33a1ea801754eb01d11b88afc86b
https://pubmed.ncbi.nlm.nih.gov/12829597

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MEDIATION: A SETTLEMENT CONFERENCE FORMAT THAT WORKS

Autor: Patrick F. Kelly

Publisher Summary This chapter presents a settlement conference format that works. The attorneys should discuss settlement with their clients before the actual conference. In addition, opposing counsel should informally explore settlement prospects w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8934587b46913b74d3bd118a847119ae
https://doi.org/10.1016/b978-0-88063-124-2.50018-1

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Constraints on Algebraically Extended Theories of Gravity

Autor: Patrick F. Kelly

Publikováno v: Gauge Theory and the Early Universe ISBN: 9789401078764

The particle spectra for all of the algebraically extended theories of gravity are presented and only those which are free of ghosts and tachyons are suggested for physical viability. Of the much smaller class of theories that pass this hurdle, one i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38d6a978744ca905bc58b21d51993fe1
https://doi.org/10.1007/978-94-009-3059-9_19

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Settlement conference format and guidelines

Autor: Patrick F. Kelly

Publikováno v: Alternatives to the High Cost of Litigation. 3:13-14

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9d38614bf58369925b26a0ea6a0450d
https://doi.org/10.1002/alt.3810031116

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