Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Patrick E. Gelbach"'
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Microbial communities play a crucial role in ecosystem function through metabolic interactions. Genome-scale modeling is a promising method to understand these interactions and identify strategies to optimize the community. Flux b
Externí odkaz:
https://doaj.org/article/68430eeee1e14322a45f8122119299d7
Autor:
Patrick E. Gelbach, Stacey D. Finley
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107569- (2023)
Summary: Colorectal cancer (CRC) shows high incidence and mortality, partly due to the tumor microenvironment (TME), which is viewed as an active promoter of disease progression. Macrophages are among the most abundant cells in the TME. These immune
Externí odkaz:
https://doaj.org/article/d1bc9229143d43949e58376e13d1c026
Autor:
Laura A. Gonyar, Patrick E. Gelbach, Dennis G. McDuffie, Alexander F. Koeppel, Qing Chen, Gloria Lee, Louise M. Temple, Scott Stibitz, Erik L. Hewlett, Jason A. Papin, F. Heath Damron, Joshua C. Eby
Publikováno v:
mSphere, Vol 4, Iss 3 (2019)
ABSTRACT Bordetella pertussis is the causative agent of whooping cough, a serious respiratory illness affecting children and adults, associated with prolonged cough and potential mortality. Whooping cough has reemerged in recent years, emphasizing a
Externí odkaz:
https://doaj.org/article/d637cd0d98204829b52e75663e7cbc25
Autor:
Patrick E. Gelbach, Stacey D. Finley
1.AbstractMicrobial communities play a crucial role in ecosystem function through metabolic interactions. Genome-scale modeling is a promising method to understand these interactions. Flux balance analysis (FBA) is most often used to predict the flux
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2989d993ef91c06b30d5c6528db70e84
https://doi.org/10.1101/2023.04.18.537368
https://doi.org/10.1101/2023.04.18.537368
Autor:
Patrick E. Gelbach, Stacey D. Finley
1SummaryColorectal cancer (CRC) shows high incidence and mortality, partly due to the tumor microenvironment, which is viewed as an active promoter of disease progression. Macrophages are among the most abundant cells in the tumor microenvironment. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7f8fdfda6e6a5d526964a46ce02f882
https://doi.org/10.1101/2023.03.09.532000
https://doi.org/10.1101/2023.03.09.532000
Autor:
Patrick E. Gelbach, Jason A. Papin, Joshua C. Eby, Gloria M. Lee, Alexander F. Koeppel, Laura A. Gonyar, Larissa K. Temple, Dennis G. McDuffie, F. Heath Damron, Scott Stibitz, Qing Chen, Erik L. Hewlett
Publikováno v:
mSphere, Vol 4, Iss 3 (2019)
mSphere
mSphere, Vol 4, Iss 3, p e00694-18 (2019)
mSphere
mSphere, Vol 4, Iss 3, p e00694-18 (2019)
Our study describes the first in vivo transposon sequencing (Tn-seq) analysis of B. pertussis and identifies genes predicted to be essential for in vivo growth in a murine model of intranasal infection, generating key resources for future investigati
Autor:
Patrick E Gelbach, Dongqing Zheng, Scott E Fraser, Kate L White, Nicholas A Graham, Stacey D Finley
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 10, p e1010555 (2022)
Pancreatic β-cells respond to increased extracellular glucose levels by initiating a metabolic shift. That change in metabolism is part of the process of glucose-stimulated insulin secretion and is of particular interest in the context of diabetes.
Externí odkaz:
https://doaj.org/article/fe77bacb0dce4ad5b98c883832f02538