Výsledky vyhledávání - "Patrick D. Scheu"

Akademický článek

Polar localization of a tripartite complex of the two-component system DcuS/DcuR and the transporter DctA in Escherichia coli depends on the sensor kinase DcuS.

Autor: Patrick D Scheu, Philipp A Steinmetz, Felix Dempwolff, Peter L Graumann, Gottfried Unden

Publikováno v: PLoS ONE, Vol 9, Iss 12, p e115534 (2014)

The C4-dicarboxylate responsive sensor kinase DcuS of the DcuS/DcuR two-component system of E. coli is membrane-bound and reveals a polar localization. DcuS uses the C4-dicarboxylate transporter DctA as a co-regulator forming DctA/DcuS sensor units.

Externí odkaz: https://doaj.org/article/d9fb50a95c364891bb2ae1efd0cfd8b3

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The sensor kinase DcuS of Escherichia coli: two stimulus input sites and a merged signal pathway in the DctA/DcuS sensor unit

Autor: Gottfried Unden, Patrick D. Scheu, Julian Witan, Christian Monzel

Publikováno v: bchm. 393:1291-1297

The membrane-integral sensor kinase DcuS of Escherichia coli consists of a periplasmically located sensory PASP domain, transmembrane helices TM1 and TM2, a cytoplasmic PASC domain and the kinase domain. Stimulus (C4-dicarboxylate) binding at PASP is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65d62c9af4a0476c14cc357cf82e573
https://doi.org/10.1515/hsz-2012-0229

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CitA/CitB Two-Component System Regulating Citrate Fermentation in Escherichia coli and Its Relation to the DcuS/DcuR System In Vivo

Autor: Yun-Feng Liao, Thomas Basché, Andrea Ebert-Jung, Gottfried Unden, Julian Witan, Patrick D. Scheu, M. Rauschmeier, Wolfgang Erker, Sabrina Graf

Publikováno v: Journal of Bacteriology. 194:636-645

Citrate fermentation by Escherichia coli requires the function of the citrate/succinate antiporter CitT ( citT gene) and of citrate lyase ( citCDEFXG genes). Earlier experiments suggested that the two-component system CitA/CitB, consisting of the mem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b02b0cf78458ebe323600377fb1944e
https://doi.org/10.1128/jb.06345-11

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Oligomeric Sensor Kinase DcuS in the Membrane of Escherichia coli and in Proteoliposomes: Chemical Cross-linking and FRET Spectroscopy

Autor: Yun-Feng Liao, Holger Kneuper, Wolfgang Erker, Patrick D. Scheu, Gottfried Unden, Thomas Basché, Julia Bauer

Publikováno v: Journal of Bacteriology. 192:3474-3483

The DcuSR (dicarboxylate uptake sensor and regulator) system of Escherichia coli is a typical two-component system consisting of a membranous sensor kinase (DcuS) and a cytoplasmic response regulator (DcuR) (11, 26, 48). DcuS responds to C4-dicarboxy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1211ccf214c50a6bdd6c404dd4eaa451
https://doi.org/10.1128/jb.00082-10

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Polar accumulation of the metabolic sensory histidine kinases DcuS and CitA in Escherichia coli

Autor: Wolfgang Erker, Thomas Basché, Gottfried Unden, Yun-Feng Liao, Patrick D. Scheu, Sven Sdorra, Maria Wegner

Publikováno v: Microbiology. 154:2463-2472

Signal transduction in prokaryotes is frequently accomplished by two-component regulatory systems in which a histidine protein kinase is the sensory component. Many of these sensory kinases control metabolic processes that do not show an obvious requ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606b66eb4fecb1e36954ac801b66b06a
https://doi.org/10.1099/mic.0.2008/018614-0

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Sensing by the membrane-bound sensor kinase DcuS: exogenous versus endogenous sensing of C(4)-dicarboxylates in bacteria

Autor: Gottfried Unden, Christian Griesinger, Patrick D. Scheu, Ok Bin Kim

Publikováno v: Future Microbiology

Bacteria are able to grow at the expense of both common (succinate, L-malate, fumarate and aspartate) and uncommon (L-tartrate and D-malate) C4-dicarboxylates, which are components of central metabolism. Two types of sensors/regulators responding to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e4afe9c09b345ffcf4219c59c5857f
https://pubmed.ncbi.nlm.nih.gov/20860483

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Polar Localization of a Tripartite Complex of the Two-Component System DcuS/DcuR and the Transporter DctA in Escherichia coli Depends on the Sensor Kinase DcuS

Autor: Gottfried Unden, Felix Dempwolff, Peter L. Graumann, Patrick D. Scheu, Philipp Aloysius Steinmetz

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 12, p e115534 (2014)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3e71c35afe2a5e78700ff80ff2a34e
https://doi.org/10.1371/journal.pone.0115534

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Akademický článek

The sensor kinase DcuS of Escherichia coli: two stimulus input sites and a merged signal pathway in the DctA/DcuS sensor unit.

Autor: Witan, Julian, Monzel, Christian, Scheu, Patrick D., Unden, Gottfried

Publikováno v: Biological Chemistry; Nov2012, Vol. 393 Issue 11, p1291-1297, 7p, 3 Diagrams

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Elektronická kniha

Sensory Mechanisms in Bacteria: Molecular Aspects of Signal Recognition

Autor: Stephen Spiro, Ray Dixon

Bacteria have evolved extraordinary abilities to regulate aspects of their behaviour (such as gene expression) in response to signals in the intracellular and extracellular environment. Key to this are the diverse macromolecules (proteins or RNA) tha

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