Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Patrick Cozzone"'
Autor:
Hwee Kuan Lee, Matthew James Frost, Mathias Bøtcher Iversen, Heng Zhao, Scott D. Solomon, Patrick Cozzone, Weimin Huang, Lieng-Hsi Ling, Justin A. Ezekowitz, Jiang Zhubo, A. Mark Richards, Carolyn S.P. Lam, Seekings Paul James, Rick Siow Mong Goh, David Sim, Jasper Tromp, Chung-Lieh Hung, Frank Eisenhaber, Wouter Ouwerkerk
Publikováno v:
Lancet digital health, 4(1), 46-54. Elsevier
The Lancet Digital Health, 4(1), e46-e54. Elsevier Ltd
The Lancet Digital Health, 4(1), e46-e54. Elsevier Ltd
Background: Echocardiography is the diagnostic modality for assessing cardiac systolic and diastolic function to diagnose and manage heart failure. However, manual interpretation of echocardiograms can be time consuming and subject to human error. Th
Autor:
Philip Lee, Patrick Cozzone, Bhanu Prakash Kn, Jeslin J. L. Tan, Teck-Hui Teo, Wei Zhang, Isaac Huen, Tze-Kwang Chua, Laurent Rénia, Jun-Jia Koh, Yiu-Wing Kam, Fok-Moon Lum, Benoit Malleret, Siti Naqiah Amrun, Kuan J. Lee, Kheng-Choon Lim, Lisa F. P. Ng, Wearn-Xin Yee
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Animal models that recapitulate the human pathophysiology have been developed as useful research tools. Although laboratory mice are widely used, they are phylogenetically “distant” to humans. New world monkeys, such as the common marmoset (Calli
Autor:
Philip Lee, Dominique P.V. de Kleijn, Zhi Wei Tay, Patrick Cozzone, Carolyn S.P. Lam, Renee R. Li, Wei‐Hsin Wang, Xing Qi Teo, Christopher J. Charles, Stephane M. Ibraham Mazlan, Desiree Abdurrachim, A. Mark Richards, Teresa Yeung
Publikováno v:
ESC Heart Failure, 7(1), 93-103. WILEY PERIODICALS, INC
ESC Heart Failure, Vol 7, Iss 1, Pp 93-103 (2020)
ESC Heart Failure
ESC Heart Failure, Vol 7, Iss 1, Pp 93-103 (2020)
ESC Heart Failure
Aims A significant proportion of heart failure (HF) patients have HF preserved ejection fraction (HFpEF). The lack of effective treatments for HFpEF remains a critical unmet need. A key obstacle to therapeutic innovation in HFpEF is the paucity of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e113aa041788e7d20aa308f507a023
https://research.rug.nl/en/publications/43b1d1e1-f489-4a64-b29f-297118b18365
https://research.rug.nl/en/publications/43b1d1e1-f489-4a64-b29f-297118b18365
Autor:
Hiroshi Hamada, Bruno Reversade, Artina Metoska, Fui Mee Ng, Jeffrey Hill, Patrick Cozzone, Nithya Baburajendran, Hülya Kayserili, Oz Pomp, Nathalie Escande-Beillard, Joyner Wong, Abigail Loh, Kohei Kanata, Sahar N. Saleem, Joanes Grandjean, Yui Hashimoto, E. Beillard, Umut Altunoglu, Hidetaka Shiratori, Maha S. Zaki
Publikováno v:
Neuron, 107, 82-94 e6
Neuron, 107(1), 82-94.e6. Cell Press
Neuron, 107, 1, pp. 82-94 e6
Neuron, 107(1), 82-94.e6. Cell Press
Neuron, 107, 1, pp. 82-94 e6
Patients lacking PYCR2, a mitochondrial enzyme that synthesizes proline, display postnatal degenerative microcephaly with hypomyelination. Here we report the crystal structure of the PYCR2 apo-enzyme and show that a novel germline p.Gly249Val mutatio
Autor:
Marius George, Linguraru, Nicholas, Ayache, Miguel Angel, González Ballester, Eric, Bardinet, Damien, Galanaud, Stéphane, Haïk, Baptiste, Faucheux, Patrick, Cozzone, Didier, Dormont, Jean-Philippe, Brandel
Publikováno v:
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. 8(Pt 2)
We present a method for the analysis of deep grey brain nuclei for accurate detection of human spongiform encephalopathy in multisequence MRI of the brain. We employ T1, T2 and FLAIR-T2 MR sequences for the detection of intensity deviations in the in
Publikováno v:
Bulletin du cancer. 92(4)
Magnetic resonance spectroscopy (MRS), that may be added to conventional magnetic resonance imaging (MRI) exam exhibit an increasing role in the management of brain tumors. These technique allow quantitative analysis of metabolites, either cell speci
Autor:
Jean-Philippe, Ranjeva, Bertrand, Audoin, My Van, Au Duong, My Van Au, Duong, Danielle, Ibarrola, Sylviane, Confort-Gouny, Irina, Malikova, Elisabeth, Soulier, Patrick, Viout, André, Ali-Chérif, Jean, Pelletier, Patrick, Cozzone
Publikováno v:
AJNR Am J Neuroradiol
BACKGROUND AND PURPOSE: In the early stage of Multiple Sclerosis (MS), conventional MR imaging parameters such as T2 lesion load fail to explain the clinical status of patients. In the present work, we aimed to determine the ability of magnification
Autor:
Bertrand, Audoin, Danielle, Ibarrola, Jean-Philippe, Ranjeva, Sylviane, Confort-Gouny, Irina, Malikova, André, Ali-Chérif, Jean, Pelletier, Patrick, Cozzone
Publikováno v:
Hum Brain Mapp
Recent functional magnetic resonance imaging (fMRI) studies have suggested that functional cortical changes seen in patients with early relapsing‐remitting multiple sclerosis (MS) can have an adaptive role to limit the clinical impact of tissue inj
Autor:
Ludwig Kappos, Giancarlo Comi, Hillel Panitch, Joel Oger, Jack Antel, Paul Conlon, Lawrence Steinman, Alexander Rae-Grant, John Castaldo, Nancy Eckert, Joseph B. Guarnaccia, Pamela Mills, Gary Johnson, Peter A. Calabresi, Carlo Pozzilli, Stefano Bastianello, Elisabetta Giugni, Tatiana Witjas, Patrick Cozzone, Jean Pelletier, Dieter Pöhlau, Horst Przuntek, Volker Hoffmann, Christopher Bever, Eleanor Katz, Michel Clanet, Isabelle Berry, David Brassat, Irene Brunet, Gilles Edan, Pierre Duquette, Ernst-Wilhelm Radue, Dagmar Schött, Carmen Lienert, Alice Taksaoui, M. Rodegher, M. Filippi, Alan Evans, Pierre Bourgouin, Alex Zijdenbos, Shawki Salem, Nicholas Ling, David Alleva, Eric Johnson, Amitabh Gaur, Paul Crowe, Xin-Jun Liu
In this ‘double-blind’, randomized, placebo-controlled phase II trial, we compared an altered peptide ligand of myelin basic protein with placebo, evaluating their safety and influence on magnetic resonance imaging in relapsing–remitting multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84abfe4e0a3448d3713b0b3f314f980c
Autor:
Thierry Chalvidan, Christiane Dalmasso, Dragos Cozma, Pierre Laurent, Jean-Claude Deharo, Pierre Djiane, Patrick Cozzone, Monique Bernard
Publikováno v:
Molecular & Cellular Biochemistry; Oct2008, Vol. 317 Issue 1/2, p69-75, 7p