Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Patrick C. Sachs"'
Autor:
Martina Zamponi, Peter A. Mollica, Yara Khodour, Julie S. Bjerring, Robert D. Bruno, Patrick C. Sachs
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
We have previously shown that human and murine breast extracellular matrix (ECM) can significantly impact cellular behavior, including stem cell fate determination. It has been established that tissue-specific extracellular matrix from the central ne
Externí odkaz:
https://doaj.org/article/ebf6f577917c464b981c1a91673613af
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-13 (2018)
Abstract Background Standard three-dimensional (3D) in vitro culture techniques, such as those used for mammary epithelial cells, rely on random distribution of cells within hydrogels. Although these systems offer advantages over traditional 2D model
Externí odkaz:
https://doaj.org/article/875beeaad55440a08b782c6a10833273
Publikováno v:
Journal of Biological Engineering, Vol 11, Iss 1, Pp 1-11 (2017)
Abstract The accumulated evidence points to the microenvironment as the primary mediator of cellular fate determination. Comprised of parenchymal cells, stromal cells, structural extracellular matrix proteins, and signaling molecules, the microenviro
Externí odkaz:
https://doaj.org/article/6b4a55bc67084b68a546f9ee81438b44
Autor:
Casey L. Roberts, Silvia S. Chen, Angela C. Murchison, Rebecca A. Ogle, Michael P. Francis, Roy C. Ogle, Patrick C. Sachs
Publikováno v:
Stem Cells International, Vol 2017 (2017)
While induced pluripotent stem cells (iPSCs) hold great clinical promise, one hurdle that remains is the existence of a parental germ-layer memory in reprogrammed cells leading to preferential differentiation fates. While it is problematic for genera
Externí odkaz:
https://doaj.org/article/e964e2c53d364dca897b493e0b6e418b
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-1 (2018)
Following publication of the original article [1], the authors reported a typesetting error in the spelling of the second author’s name.
Externí odkaz:
https://doaj.org/article/d8872fc0f0644722879ef2ceb6034355
Autor:
Elizabeth N. Booth-Creech, Shea M. Sullivan, Patrick C. Sachs, Robert D. Bruno, Xavier-Lewis Palmer, Martina Zamponi, Peter A. Mollica, John A. Reid
Publikováno v:
Acta Biomater
The extracellular matrix (ECM) of tissues is an important mediator of cell function. Moreover, understanding cellular dynamics within their specific tissue context is also important for developmental biology, cancer research, and regenerative medicin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b5e237c714fa85c797ac93aeeff627
https://doi.org/10.1016/j.actbio.2019.06.017
https://doi.org/10.1016/j.actbio.2019.06.017
Autor:
Roy C. Ogle, Rebecca A. Ogle, Patrick C. Sachs, Michael Francis, Casey L. Roberts, Angela C. Murchison, Silvia S. Chen
Publikováno v:
Stem Cells International
Stem Cells International, Vol 2017 (2017)
Stem Cells International, Vol 2017 (2017)
While induced pluripotent stem cells (iPSCs) hold great clinical promise, one hurdle that remains is the existence of a parental germ-layer memory in reprogrammed cells leading to preferential differentiation fates. While it is problematic for genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd643b11f15a5f4118d58e9793dfc08f
https://doi.org/10.1155/2017/1513281
https://doi.org/10.1155/2017/1513281
Autor:
Patrick C. Sachs, Nicole Northam, Robert D. Bruno, Xavier-Lewis Palmer, John A. Reid, Peter A. Mollica
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
The normal mammary microenvironment can suppress tumorigenesis and redirect cancer cells to adopt a normal mammary epithelial cell fate in vivo. Understanding of this phenomenon offers great promise for novel treatment and detection strategies in can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b58c611ed2f7aae8e38c1eb59ba8a2
https://doi.org/10.1038/s41598-019-43922-z
https://doi.org/10.1038/s41598-019-43922-z
Publikováno v:
Breast Cancer Research : BCR
Background Standard three-dimensional (3D) in vitro culture techniques, such as those used for mammary epithelial cells, rely on random distribution of cells within hydrogels. Although these systems offer advantages over traditional 2D models, limita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740230da7953a904a9a8a1dff4d3126e
https://pubmed.ncbi.nlm.nih.gov/30305139
https://pubmed.ncbi.nlm.nih.gov/30305139
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 20, Iss 1, Pp 1-1 (2018)
Breast Cancer Research, Vol 20, Iss 1, Pp 1-1 (2018)
Following publication of the original article [1], the authors reported a typesetting error in the spelling of the second author’s name.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c202d5dcee0d6d164ba4362ba8bee4
http://europepmc.org/articles/PMC6245868
http://europepmc.org/articles/PMC6245868