Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Patrick C. Reid"'
Autor:
Dawei Sun, Kelly M. Storek, Dimitry Tegunov, Ying Yang, Christopher P. Arthur, Matthew Johnson, John G. Quinn, Weijing Liu, Guanghui Han, Hany S. Girgis, Mary Kate Alexander, Austin K. Murchison, Stephanie Shriver, Christine Tam, Hiroshi Ijiri, Hiroko Inaba, Tatsuya Sano, Hayato Yanagida, Junichi Nishikawa, Christopher E. Heise, Wayne J. Fairbrother, Man-Wah Tan, Nicholas Skelton, Wendy Sandoval, Benjamin D. Sellers, Claudio Ciferri, Peter A. Smith, Patrick C. Reid, Christian N. Cunningham, Steven T. Rutherford, Jian Payandeh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract BamA is the central component of the essential β-barrel assembly machine (BAM), a conserved multi-subunit complex that dynamically inserts and folds β-barrel proteins into the outer membrane of Gram-negative bacteria. Despite recent advanc
Externí odkaz:
https://doaj.org/article/bf48c6d78a39468c81c644c4c61faa56
Autor:
Yasuomi Urano, Ikuo Hayashi, Noriko Isoo, Patrick C. Reid, Yoshikazu Shibasaki, Noriko Noguchi, Taisuke Tomita, Takeshi Iwatsubo, Takao Hamakubo, Tatsuhiko Kodama
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 5, Pp 904-912 (2005)
Cholesterol has been implicated in the pathogenesis of Alzheimer's disease (AD). Although the underlying mechanisms are not yet clear, several studies have provided evidence for the involvement of cholesterol-rich lipid rafts in the production of amy
Externí odkaz:
https://doaj.org/article/437b6b409817495dbd404afba2ab5136
Autor:
Yoshio Yamauchi, Catherine C.Y. Chang, Michi Hayashi, Sumiko Abe-Dohmae, Patrick C. Reid, Ta-Yuan Chang, Shinji Yokoyama
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 10, Pp 1943-1951 (2004)
Differential regulation has been suggested for cellular cholesterol and phospholipid release mediated by apolipoprotein A-I (apoA-I)/ABCA1. We investigated various factors involved in cholesterol mobilization related to this pathway. ApoA-I induced a
Externí odkaz:
https://doaj.org/article/11044ae0feed4d01950467b71c93054e
Autor:
Patrick C. Reid, Naomi Sakashita, Shigeki Sugii, Yoshiko Ohno-Iwashita, Yukiko Shimada, William F. Hickey, Ta-Yuan Chang
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 3, Pp 582-591 (2004)
Niemann-Pick type C (NPC) is a neurodegenerative disorder characterized by progressive accumulation of cholesterol, gangliosides, and other lipids in the central nervous system and visceral organs. In the NPC1 mouse model, neurodegeneration and neuro
Externí odkaz:
https://doaj.org/article/bea23713b1544e268d826f433828d7b1
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 5, Pp 1010-1019 (2003)
Niemann-Pick type C1 disease (NPC1) is an inherited neurovisceral lipid storage disorder, hallmarked by the intracellular accumulation of unesterified cholesterol and glycolipids in endocytic organelles. Cells acquire cholesterol through exogenous up
Externí odkaz:
https://doaj.org/article/37045ac78d764af9a6cb8e25dd7920e3
Autor:
Shigeki Sugii, Patrick C. Reid, Nobutaka Ohgami, Yukiko Shimada, Robert A. Maue, Haruaki Ninomiya, Yoshiko Ohno-Iwashita, Ta-Yuan Chang
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 5, Pp 1033-1041 (2003)
BCθ is a proteolytically nicked and biotinylated derivative of a cholesterol binding protein perfringolysin O (θ-toxin), and has been used to detect cholesterol-rich domains at the plasma membrane (PM). Here we show that by modifying the cell fixat
Externí odkaz:
https://doaj.org/article/126374b3ddf84e7dac98a60a4e3ae71d
Autor:
Yannick Mesrouze, Hanspeter Gubler, Frédéric Villard, Ralf Boesch, Johannes Ottl, Joerg Kallen, Patrick C. Reid, Clemens Scheufler, Andreas L. Marzinzik, Patrick Chène
Publikováno v:
ACS Chemical Biology. 18:643-651
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4808188d8d2d91d270aa5073b3cd649
https://doi.org/10.1021/acschembio.2c00936
https://doi.org/10.1021/acschembio.2c00936
Autor:
Samuel Hintermann, Andreas Marzinzik, Johannes Ottl, Joerg Kallen, Therese-Marie Stachyra, Patrick C. Reid, Stephan Ruetz, Anselm F. L. Schneider, Christian P. R. Hackenberger, Christoph E. Dumelin, Sebastien Ripoche
Publikováno v:
RSC Chemical Biology
Mouse double minute 2 homolog (MDM2, Hdm2) is an important negative regulator of the tumor suppressor p53. Using a mRNA based display technique to screen a library of >1012in vitro-translated cyclic peptides, we have identified a macrocyclic ligand t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79c0089311703a726113d94f5b84104
http://europepmc.org/articles/PMC8637822
http://europepmc.org/articles/PMC8637822
Autor:
Christian M. Gampe, Jingzhou Li, Patel Tajesh Jayprakash, Jakal Amin, Charles Babu, Lihua Yang, Eugene Liu, Andrei Golosov, Katsumasa Nakajima, David Nettleton, Patrick C. Reid, Lauren G. Monovich, Flyer Alec
Publikováno v:
Journal of Medicinal Chemistry. 64:2622-2633
Advances in the design of permeable peptides and in the synthesis of large arrays of macrocyclic peptides with diverse amino acids have evolved on parallel but independent tracks. Less precedent combines their respective attributes, thereby limiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2dd9795db77b2153f204b31c1dd80d9
https://doi.org/10.1021/acs.jmedchem.0c01505
https://doi.org/10.1021/acs.jmedchem.0c01505
Autor:
James Lin, Louis F. Amorosa, Meghan Cerpa, Michael P. Kelly, Lawrence G. Lenke, Richard Menger, Griffin R. Baum, Peter D. Angevine, Marc D. Dyrszka, Christopher E. Mandigo, Patrick C. Reid, Zeeshan M. Sardar, Joseph A Osorio
Publikováno v:
Spine Deformity. 9:175-183
To propose and test the reliability of a radiographic classification system for adult idiopathic scoliosis. A three-component radiographic classification for adult idiopathic scoliosis consisting of curve type, a lumbosacral modifier, and a global al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e749ea38ac7793e5bd8375dccc7668d
https://doi.org/10.1007/s43390-020-00181-7
https://doi.org/10.1007/s43390-020-00181-7