Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Patrick C. M. Vermote"'
Autor:
Marian Geldof, Meindert Danhof, Patrick C. M. Vermote, Ludy van Beijsterveldt, Jan Freijer, Anton Megens
Publikováno v:
European Journal of Pharmaceutical Sciences. 32:200-208
The pharmacokinetic-pharmacodynamic (PK-PD) correlation of the effect of fluvoxamine on para-chloroamphetamine (PCA)-induced behavior was determined in the rat. Rats (n=66) with permanent arterial and venous cannulas received a 30-min intravenous inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858b21412efc3204bcfd79dfb1e33a0e
https://doi.org/10.1016/j.ejps.2007.07.004
https://doi.org/10.1016/j.ejps.2007.07.004
Autor:
Margot H. Bakker, Ilse Biesmans, Anton Megens, Koen A. Hens, Sonia Martı́nez, J. Alonso, Joaquín Pastor, J.Ignacio Andrés, Ana Isabel de Lucas, Ilse Lenaerts, Javier Fernández, Thomas Steckler, Laura Iturrino, Luis M. Font, Patrick C. M. Vermote, José María Cid, Jesús Alcázar, Rosa M. Alvarez
Publikováno v:
Journal of Medicinal Chemistry. 48:2054-2071
The synthesis and pharmacology of a new series of 3-piperazinylmethyl-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazoles that combine central serotonin (5-HT) reuptake inhibition with alpha(2)-adrenoceptor blocking activity is described as potential ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe19d273ff1de6df5fb25e7aa4991c3
https://doi.org/10.1021/jm049619s
https://doi.org/10.1021/jm049619s
Publikováno v:
Drug Development Research. 19:353-373
The results presented here indicate that 0.16 mg/kg LSD, 2.50 mg/kg 8-OHDPAT, 1.25 mg/kg d-amphetamine, 10.00 mg/kg cocaine, 40.00 mg/kg chlordiazepoxide, 2.50 mg/kg xylazine, and 0.04 mg/kg fentanyl can be used as discriminative stimuli in a two-lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31565eeb4664258c8b7298f30ddbc8fc
https://doi.org/10.1002/ddr.430190403
https://doi.org/10.1002/ddr.430190403
Publikováno v:
Animal Models in Psychopharmacology ISBN: 9783034864213
R 79598, a new potent neuroleptic, was compared with haloperidol and risperidone in a drug discrimination test procedure in rats. Generalization and antagonism studies were performed in rats trained to discriminate either LSD, DOM, d-amphetamine, coc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be0585f26d88c129a8eb5f26435ef6b3
https://doi.org/10.1007/978-3-0348-6419-0_36
https://doi.org/10.1007/978-3-0348-6419-0_36
Autor:
Carlos J. E. Niemegeers, Frans Awouters, Jozef Vermeire, Frans Smeyers, Patrick C. M. Vermote, René van Beek
Publikováno v:
Drug Development Research. 8:95-102
The antiallergic effectiveness of twelve compounds was studied in ascaris hypersensitive dogs by measuring allergen-induced skin reactions before and 1, 4, 20, and 72 hr after oral treatment. The specific serotonin S2-antagonist ritanserin at 2.5 mg/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c1e131888f50a1fd245e228f193b877
https://doi.org/10.1002/ddr.430080112
https://doi.org/10.1002/ddr.430080112