Zobrazeno 1 - 10
of 292
pro vyhledávání: '"Patrick C. D'Haese"'
Autor:
Catarina Meng, Hanne Skou Jørgensen, Lieve Verlinden, Nathalie Bravenboer, Henriette de Loor, Patrick C. D'Haese, Geert Carmeliet, Pieter Evenepoel
Publikováno v:
Bone Reports, Vol 16, Iss , Pp 101172- (2022)
Bone microarchitecture is an important component of bone quality and disturbances may reduce bone strength and resistance to trauma. Kidney transplant recipients have an excess risk of fractures, and bone loss affecting both trabecular and cortical b
Externí odkaz:
https://doaj.org/article/60f320836ea749d299c5a1a3190b0dc1
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 9043 (2023)
Diabetic Kidney Disease (DKD) is a major microvascular complication for diabetic patients and is the most common cause of chronic kidney disease (CKD) and end-stage renal disease. Antidiabetic drugs, such as metformin and canagliflozin, have been sho
Externí odkaz:
https://doaj.org/article/7698efe8755c437a99a28e16ed921b8d
Autor:
Antonia E. Schantl, Anja Verhulst, Ellen Neven, Geert J. Behets, Patrick C. D’Haese, Marc Maillard, David Mordasini, Olivier Phan, Michel Burnier, Dany Spaggiari, Laurent A. Decosterd, Mark G. MacAskill, Carlos J. Alcaide-Corral, Adriana A. S. Tavares, David E. Newby, Victoria C. Beindl, Roberto Maj, Anne Labarre, Chrismita Hegde, Bastien Castagner, Mattias E. Ivarsson, Jean-Christophe Leroux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Cardiovascular calcification is a serious pathology for which effective pharmacological treatments are lacking. Here the authors show that an optimized oligo(ethylene glycol) derivative of inositol phosphate interferes with calcium phosphate crystall
Externí odkaz:
https://doaj.org/article/af7eef951f974f1d9573843564c6bad9
Autor:
Britt Opdebeeck, Ellen Neven, Stuart Maudsley, Hanne Leysen, Deborah Walter, Hilde Geryl, Patrick C. D’Haese, Anja Verhulst
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3657 (2023)
Arterial media calcification refers to the pathological deposition of calcium phosphate crystals in the arterial wall. This pathology is a common and life-threatening complication in chronic kidney disease, diabetes and osteoporosis patients. Recentl
Externí odkaz:
https://doaj.org/article/1818903f59b84d99813b32d55d7183f6
Autor:
Yentl Huybrechts, Pieter Evenepoel, Mathias Haarhaus, Etienne Cavalier, Geert Dams, Wim Van Hul, Patrick C. D’Haese, Anja Verhulst
Publikováno v:
Nutrients, Vol 15, Iss 3, p 598 (2023)
Renal osteodystrophy (ROD) is a complex and serious complication of chronic kidney disease (CKD), a major global health problem caused by loss of renal function. Currently, the gold standard to accurately diagnose ROD is based on quantitative histomo
Externí odkaz:
https://doaj.org/article/b344f9a6c8094da4b9ed635386fd590f
Autor:
Jeremy Rott, Eva Teresa Toepfer, Maria Bartosova, Ana Kolevica, Alexander Heuser, Michael Rabe, Geert Behets, Patrick C. D’Haese, Viktoria Eichwald, Manfred Jugold, Ivan Damgov, Sotirios G. Zarogiannis, Rukshana Shroff, Anton Eisenhauer, Claus Peter Schmitt
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7796 (2022)
Serum calcium isotopes (δ44/42Ca) have been suggested as a non-invasive and sensitive Ca balance marker. Quantitative δ44/42Ca changes associated with Ca flux across body compartment barriers relative to the dietary Ca and the correlation of δ44/4
Externí odkaz:
https://doaj.org/article/4f233d10398e40e5b16d1a5a6ab0adbe
Publikováno v:
BMC Nephrology, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Acute kidney injury (AKI) is an underestimated, yet important, risk factor for the development of chronic kidney disease (CKD). Persistence of inflammation after a renal ischemic injury has been observed, both in experimental mode
Externí odkaz:
https://doaj.org/article/2a0c6106472a4a46a9ae0ce7762ac363
Publikováno v:
Metabolites, Vol 12, Iss 4, p 327 (2022)
The presence of arterial media calcification, a highly complex and multifactorial disease, puts patients at high risk for developing serious cardiovascular consequences and mortality. Despite the numerous insights into the mechanisms underlying this
Externí odkaz:
https://doaj.org/article/a619bdc985614985a3c872d4801b2854
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12767 (2021)
One of the most important risk factors for developing chronic kidney disease (CKD) is diabetes. To assess the safety and efficacy of potential drug candidates, reliable animal models that mimic human diseases are crucial. However, a suitable model of
Externí odkaz:
https://doaj.org/article/7e4e8fd08f604946aa679145ceee5575
Autor:
Britt Opdebeeck, Ellen Neven, José Luis Millán, Anthony B. Pinkerton, Patrick C. D’Haese, Anja Verhulst
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1138 (2021)
Patients with chronic kidney disease (CKD) suffer from arterial media calcification and a disturbed bone metabolism. Tissue-nonspecific alkaline phosphatase (TNAP) hydrolyzes the calcification inhibitor pyrophosphate (PPi) into inorganic phosphate (P
Externí odkaz:
https://doaj.org/article/b24f5325eb034c2e911dcef9b2c84cff