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CCR5 blockade in rheumatoid arthritis: a randomised, double-blind, placebo-controlled clinical trial
Autor:
Arno W R, van Kuijk, Clarissa E, Vergunst, Danielle M, Gerlag, Barry, Bresnihan, Juan J, Gomez-Reino, Regine, Rouzier, Patrick C, Verschueren, Christiaan, van der Leij, Christiaan, van de Leij, Mario, Maas, Maarten C, Kraan, Paul P, Tak
Publikováno v:
Annals of the rheumatic diseases, 69(11), 2013-2016. BMJ Publishing Group
Annals of the Rheumatic Diseases, 69(11), 2013-2016. BMJ Publishing Group
Annals of the Rheumatic Diseases, 69(11), 2013-2016. BMJ Publishing Group
ObjectiveC-C chemokine receptor type 5 (CCR5), a chemokine receptor expressed on T cells and macrophages, and its ligands are found in inflamed synovial tissue (ST) of patients with rheumatoid arthritis (RA). The rationale for testing CCR5 blockade i