Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Patrick C, Phillips"'
Autor:
Anastasia A Teterina, John H Willis, Matt Lukac, Richard Jovelin, Asher D Cutter, Patrick C Phillips
Publikováno v:
PLoS Genetics, Vol 19, Iss 8, p e1010879 (2023)
Caenorhabditis nematodes form an excellent model for studying how the mode of reproduction affects genetic diversity, as some species reproduce via outcrossing whereas others can self-fertilize. Currently, chromosome-level patterns of diversity and r
Externí odkaz:
https://doaj.org/article/d17da46ea973459db46951865102cf36
Autor:
Zachary C Stevenson, Megan J Moerdyk-Schauwecker, Stephen A Banse, Dhaval S Patel, Hang Lu, Patrick C Phillips
Publikováno v:
eLife, Vol 12 (2023)
High-throughput transgenesis using synthetic DNA libraries is a powerful method for systematically exploring genetic function. Diverse synthesized libraries have been used for protein engineering, identification of protein–protein interactions, cha
Externí odkaz:
https://doaj.org/article/bfdbc13377384f3aa3ceba9921feba5a
Autor:
Eric W. Hammerschmith, Gavin C. Woodruff, Kimberly A. Moser, Erik Johnson, Patrick C. Phillips
Publikováno v:
BMC Zoology, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Background Body size is a fundamental organismal trait. However, as body size and ecological contexts change across developmental time, evolutionary divergence may cause unexpected patterns of body size diversity among developmental stages.
Externí odkaz:
https://doaj.org/article/aca74559c2cf4738a075f8a62e9037c2
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 10, Pp 3775-3782 (2020)
Externí odkaz:
https://doaj.org/article/8acfe8d3fbcd4d4d9fbe578712644fc5
Autor:
Katja R Kasimatis, Megan J Moerdyk-Schauwecker, Ruben Lancaster, Alexander Smith, John H Willis, Patrick C Phillips
Publikováno v:
PLoS Genetics, Vol 18, Iss 2, p e1010063 (2022)
Sexual reproduction is a complex process that contributes to differences between the sexes and divergence between species. From a male's perspective, sexual selection can optimize reproductive success by acting on the variance in mating success (pre-
Externí odkaz:
https://doaj.org/article/0f06aa36ae4d412ca4d8b2bc60f04907
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3813-3824 (2019)
Since the autosomal genome is shared between the sexes, sex-specific fitness optima present an evolutionary challenge. While sexually antagonistic selection might favor different alleles within females and males, segregation randomly reassorts allele
Externí odkaz:
https://doaj.org/article/ee68887b530a42d28ba4669383ee3206
Autor:
Kristin L. Sikkink, Rose M. Reynolds, Catherine M. Ituarte, William A. Cresko, Patrick C. Phillips
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 3, Pp 969-982 (2019)
Organisms can cope with stressful environments via a combination of phenotypic plasticity at the individual level and adaptation at the population level. Changes in gene expression can play an important role in both. Significant advances in our under
Externí odkaz:
https://doaj.org/article/521a16f2c42844308534c2a667a0e4c2
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Variation in body size is thought to be a major driver of a wide variety of ecological and evolutionary patterns, including changes in development, reproduction, and longevity. Additionally, drastic changes in natural context ofte
Externí odkaz:
https://doaj.org/article/28786e108f2b4b6389ef06f2c4c17d66
Autor:
Christine H O’Connor, Kristin L Sikkink, Thomas C Nelson, Janna L Fierst, William A Cresko, Patrick C Phillips
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 4 (2021)
AbstractThe adaptation of complex organisms to changing environments has been a central question in evolutionary quantitative genetics since its inception. The structure of the genotype–phenotype maps is critical because pleiotropic effects can gen
Externí odkaz:
https://doaj.org/article/5b82f49121894bf881773fe3fd6efeea
Autor:
Gavin C. Woodruff, Patrick C. Phillips
Publikováno v:
BMC Ecology, Vol 18, Iss 1, Pp 1-16 (2018)
Abstract Background Biotic interactions are ubiquitous and require information from ecology, evolutionary biology, and functional genetics in order to be understood. However, study systems that are amenable to investigations across such disparate fie
Externí odkaz:
https://doaj.org/article/02b9f806962041b59661cfb49d62d52e