Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Patrick C, Baer"'
Autor:
Anna Schwantes, Anja Wickert, Sabrina Becker, Patrick C. Baer, Andreas Weigert, Bernhard Brüne, Dominik C. Fuhrmann
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103093- (2024)
Solid tumors are characterized by hypoxic areas, which are prone for macrophage infiltration. Once infiltrated, macrophages polarize to tumor associated macrophages (TAM) to support tumor progression. Therefore, the crosstalk between TAMs and tumor c
Externí odkaz:
https://doaj.org/article/2f91d336715c4328869022b52a7eb8da
Autor:
Benjamin Koch, Maximilian Filzmayer, Sammy Patyna, Nils Wetzstein, Sebastian Lampe, Tobias Schmid, Helmut Geiger, Patrick C. Baer, Olga Dolnik
Publikováno v:
Virus Research, Vol 342, Iss , Pp 199337- (2024)
Marburg virus, a member of the Filoviridae, is the causative agent of Marburg virus disease (MVD), a hemorrhagic fever with a case fatality rate of up to 90 %. Acute kidney injury is common in MVD and is associated with increased mortality, but its p
Externí odkaz:
https://doaj.org/article/a4a1b98c21804f4d9bb550fb97b21a12
Autor:
Benjamin Koch, Mahmoud Shehata, Christin Müller-Ruttloff, Shady A. Gouda, Nils Wetzstein, Sammy Patyna, Anica Scholz, Tobias Schmid, Ursula Dietrich, Christian Münch, John Ziebuhr, Helmut Geiger, Luis Martinez-Sobrido, Patrick C. Baer, Ahmed Mostafa, Stephan Pleschka
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionInfluenza A virus (IAV) infection can cause the often-lethal acute respiratory distress syndrome (ARDS) of the lung. Concomitantly, acute kidney injury (AKI) is frequently noticed during IAV infection, correlating with an increased mortal
Externí odkaz:
https://doaj.org/article/7ab24c6b07b54d538909b968359b9e77
Autor:
Olesya Vakhrusheva, Holger H. H. Erb, Vitus Bräunig, Sascha D. Markowitsch, Patricia Schupp, Patrick C. Baer, Kimberly Sue Slade, Anita Thomas, Igor Tsaur, Martin Puhr, Zoran Culig, Jindrich Cinatl, Martin Michaelis, Thomas Efferth, Axel Haferkamp, Eva Juengel
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Novel therapeutic strategies are urgently needed for advanced metastatic prostate cancer (PCa). Phytochemicals used in Traditional Chinese Medicine seem to exhibit tumor suppressive properties. Therefore, the therapeutic potential of artesunate (ART)
Externí odkaz:
https://doaj.org/article/e8bf3189c0f242e381ae779a1a745f9c
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Hematopoietic stem cell transplantation (HSCT) has been proposed as a promising therapeutic opportunity to improve immunity and prevent hematologic malignancies in Ataxia-telangiectasia (A-T). However, experience in the transplantation strategy for A
Externí odkaz:
https://doaj.org/article/67d4c07cd3d0490e99a2d34611bd7177
Autor:
Ruth Duecker, Patrick C. Baer, Aileen Buecker, Sabine Huenecke, Lisa-Marie Pfeffermann, Ute Modlich, Shahrzad Bakhtiar, Peter Bader, Stefan Zielen, Ralf Schubert
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Ataxia-telangiectasia (A-T) is a multisystem disorder with progressive cerebellar ataxia, immunodeficiency, chromosomal instability, and increased cancer susceptibility. Cellular immunodeficiency is based on naïve CD4+ and CD8+ T-cell ly
Externí odkaz:
https://doaj.org/article/e8754e915039445e99bd174d0002e63f
Autor:
Patrick C. Baer
Publikováno v:
Cells, Vol 9, Iss 9, p 1997 (2020)
Adipose tissue is a rich, ubiquitous, and easily accessible source for multipotent mesenchymal stromal/stem cells (MSCs), so-called adipose-derived stromal/stem cells (ASCs) [...]
Externí odkaz:
https://doaj.org/article/3b318ea4276b43d6b5ca70bfad4d801f
Autor:
Patrick C. Baer, Julia Sann, Ruth Pia Duecker, Evelyn Ullrich, Helmut Geiger, Peter Bader, Stefan Zielen, Ralf Schubert
Publikováno v:
Cells, Vol 9, Iss 6, p 1444 (2020)
Pulmonary failure is the main cause of morbidity and mortality in the human chromosomal instability syndrome Ataxia-telangiectasia (A-T). Major phenotypes include recurrent respiratory tract infections and bronchiectasis, aspiration, respiratory musc
Externí odkaz:
https://doaj.org/article/ca2ea4e8e947428489a9c354f9e10f97
Autor:
Patrick C. Baer, Benjamin Koch, Elena Hickmann, Ralf Schubert, Jindrich Cinatl, Ingeborg A. Hauser, Helmut Geiger
Publikováno v:
Cells, Vol 8, Iss 11, p 1346 (2019)
Mesenchymal stromal/stem cells (MSCs) are immature multipotent cells, which represent a rare population in the perivascular niche within nearly all tissues. The most abundant source to isolate MSCs is adipose tissue. Currently, perirenal adipose tiss
Externí odkaz:
https://doaj.org/article/8ae7963e64cf4ab0882748768a251d52
Autor:
Benjamin, Koch, Alec, Geßner, Samira, Farmand, Dominik C, Fuhrmann, Andreas G, Chiocchetti, Ralf, Schubert, Patrick C, Baer
Publikováno v:
International journal of molecular sciences. 23(13)
Mesenchymal stromal/stem cells and their derivates are the most promising cell source for cell therapies in regenerative medicine. The application of extracellular vesicles (EVs) as cell-free therapeuticals requires particles with a maximum regenerat