Zobrazeno 1 - 10
of 40 316
pro vyhledávání: '"Patrick C"'
Autor:
Patrick Vizeli, Erich Studerus, Friederike Holze, Yasmin Schmid, Patrick C. Dolder, Laura Ley, Isabelle Straumann, Anna M. Becker, Felix Müller, Denis Arikci, Matthias E. Liechti
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The pharmacodynamic effects of lysergic acid diethylamide (LSD) are diverse and different in different individuals. Effects of other psychoactive substances have been shown to be critically influenced by non-pharmacological factors such as p
Externí odkaz:
https://doaj.org/article/dff35d6d882c495e9ff0f88889429865
Autor:
Melkamu B. Tessema, Shouya Feng, Daniel Enosi Tuipulotu, Rubaiyea Farrukee, Chinh Ngo, Catarina Gago da Graça, Masahiro Yamomoto, Daniel T. Utzschneider, Andrew G. Brooks, Sarah L. Londrigan, Si Ming Man, Patrick C. Reading
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Dynamin-like GTPase proteins, including myxoma (Mx) and guanylate-binding proteins (GBPs), are among the many interferon stimulated genes induced following viral infections. While studies report that human (h)GBPs inhibit different viruses i
Externí odkaz:
https://doaj.org/article/ceb6b8a352e24988803a092b6ca91a95
Autor:
Melanie Modder, Claudia P. Coomans, Dirk-Jan Saaltink, Mayke M. H. Tersteeg, Janna Hoogduin, Leonie Scholten, Amanda C. M. Pronk, Reshma A. Lalai, Anita Boelen, Andries Kalsbeek, Patrick C. N. Rensen, Erno Vreugdenhil, Sander Kooijman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Crosstalk between peripheral metabolic organs and the central nervous system is essential for body weight control. At the base of the hypothalamus, β-tanycytes surround the portal capillaries and function as gatekeepers to facilitate transf
Externí odkaz:
https://doaj.org/article/dfe49dbfc38e4ce386cd77ee4e307ebf
Autor:
Jason Fontana, David Sparkman-Yager, Ian Faulkner, Ryan Cardiff, Cholpisit Kiattisewee, Aria Walls, Tommy G. Primo, Patrick C. Kinnunen, Hector Garcia Martin, Jesse G. Zalatan, James M. Carothers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Engineering metabolism to efficiently produce chemicals from multi-step pathways requires optimizing multi-gene expression programs to achieve enzyme balance. CRISPR-Cas transcriptional control systems are emerging as important tools for pro
Externí odkaz:
https://doaj.org/article/5e3002d716ec47ceb8dca2261e3ce3bb
Autor:
James Thorburn, Patrick C. Collins, Amy Garbett, Heather Vance, Natasha Phillips, Alan Drumm, Joseph Cooney, Catherine Waters, Niall Ó’Maoiléidigh, Emmett Johnston, Haley R. Dolton, Simon Berrow, Graham Hall, Jackie Hall, Diego Delvillar, Ross McGill, Fred Whoriskey, Nann A. Fangue, Alexandra G. McInturf, Andrew L. Rypel, Richard Kennedy, Jessie Lilly, Jessica R. Rodger, Colin E. Adams, Nienke C. F. van Geel, Denise Risch, Lorna Wilkie, Suzanne Henderson, Paul A. Mayo, Paul J. Mensink, Matthew J. Witt, Lucy A. Hawkes, A. Peter Klimley, Jonathan D. R. Houghton
Publikováno v:
Animal Biotelemetry, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Acoustic telemetry can provide valuable space-use data for a range of marine species. Yet the deployment of species-specific arrays over vast areas to gather data on highly migratory vertebrates poses formidable challenges, often rendering i
Externí odkaz:
https://doaj.org/article/fa177e96caa640e3a9c7ed345c1fe8bd
Autor:
Carlijn A Hoekx, Borja Martinez-Tellez, Maaike E Straat, Magdalena M A Verkleij, Mirjam Kemmeren, Sander Kooijman, Martin Uhrbom, Saskia C A de Jager, Patrick C N Rensen, Mariëtte R Boon
Publikováno v:
Endocrine Connections, Vol 13, Iss 7, Pp 1-10 (2024)
Objectives: Cold exposure is linked to cardiometabolic benefits. Cold activates brown adipose tissue (BAT), increases energy expenditure, and induces secretion of the hormones fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (
Externí odkaz:
https://doaj.org/article/0be410fb04c2444f94093ce16ab04b39
Autor:
Rubaiyea Farrukee, Lara S. U. Schwab, James B. Barnes, Andrew G. Brooks, Sarah L. Londrigan, Gunther Hartmann, Thomas Zillinger, Patrick C. Reading
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Myxovirus resistance (Mx) proteins are products of interferon stimulated genes (ISGs) and Mx proteins of different species have been reported to mediate antiviral activity against a number of viruses, including influenza A viruses (IAV). Fer
Externí odkaz:
https://doaj.org/article/4f11a884256f454cb786cbb7c1250c09
Autor:
Sergio Cruz-León, Tomáš Majtner, Patrick C. Hoffmann, Jan Philipp Kreysing, Sebastian Kehl, Maarten W. Tuijtel, Stefan L. Schaefer, Katharina Geißler, Martin Beck, Beata Turoňová, Gerhard Hummer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Visual proteomics attempts to build atlases of the molecular content of cells but the automated annotation of cryo electron tomograms remains challenging. Template matching (TM) and methods based on machine learning detect structural signatu
Externí odkaz:
https://doaj.org/article/9efba2ab8fa94381990b79eae1c1bcef
Autor:
Meghan C. Hughes, Sofhia V. Ramos, Aditya N. Brahmbhatt, Patrick C. Turnbull, Nazari N. Polidovitch, Madison C. Garibotti, Uwe Schlattner, Thomas J. Hawke, Jeremy A. Simpson, Peter H. Backx, Christopher GR. Perry
Publikováno v:
Redox Biology, Vol 76, Iss , Pp 103319- (2024)
Mitochondrial creatine kinase (mtCK) regulates the “fast” export of phosphocreatine to support cytoplasmic phosphorylation of ADP to ATP which is more rapid than direct ATP export. Such “creatine-dependent” phosphate shuttling is attenuated i
Externí odkaz:
https://doaj.org/article/a74cffb251704d729df4c25f1d7a8846
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/5dea7a3cad124ef7b4b53c195434ef35