Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Patrick Buschor"'
Autor:
Patrick Buschor, Daniel Brigger, Gabriel Hobi, Clemens A. Dahinden, Fabian Zellweger, Alexander Eggel, Peter M. Villiger
Publikováno v:
Cell Death and Disease, Vol 9, Iss 5, Pp 1-12 (2018)
Zellweger, Fabian; Buschor, Patrick; Hobi, Gabriel; Brigger, Daniel; Dahinden, Clemens A.; Villiger, Peter; Eggel, Alexander (2018). IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils. Cell death & disease, 9(5), p. 510. Nature Publishing Group 10.1038/s41419-018-0526-9
Cell Death & Disease
Zellweger, Fabian; Buschor, Patrick; Hobi, Gabriel; Brigger, Daniel; Dahinden, Clemens A.; Villiger, Peter; Eggel, Alexander (2018). IL-3 but not monomeric IgE regulates FcεRI levels and cell survival in primary human basophils. Cell death & disease, 9(5), p. 510. Nature Publishing Group 10.1038/s41419-018-0526-9
Cell Death & Disease
Binding of allergen-specific IgE to its primary receptor FcεRI on basophils and mast cells represents a central event in the development of allergic diseases. The high-affinity interaction between IgE and FcεRI results in permanent sensitization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708e9cfdba15e41541abe69f5088b054
https://doi.org/10.1038/s41419-018-0526-9
https://doi.org/10.1038/s41419-018-0526-9
Publikováno v:
Immunity, Inflammation and Disease
Fellmann, Marc; Buschor, Patrick; Röthlisberger, Silvan; Zellweger, Fabian; Vogel, Monique (2015). High affinity targeting of CD23 inhibits IgE synthesis in human B cells. Immunity, inflammation and disease, 3(4), pp. 339-349. Wiley 10.1002/iid3.72
Fellmann, Marc; Buschor, Patrick; Röthlisberger, Silvan; Zellweger, Fabian; Vogel, Monique (2015). High affinity targeting of CD23 inhibits IgE synthesis in human B cells. Immunity, inflammation and disease, 3(4), pp. 339-349. Wiley 10.1002/iid3.72
The low‐affinity IgE receptor FcϵRII (CD23) is part of the regulatory system controlling IgE synthesis in human B cells and exists in membrane and soluble forms. Binding of IgE to CD23 has been described to have stabilizing effects and to prevent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131c0b9954a9385126d1498dcee2c0aa
http://europepmc.org/articles/PMC4693728
http://europepmc.org/articles/PMC4693728
Publikováno v:
International Archives of Allergy and Immunology. 163:206-214
Background: Mast cells and basophils express the high-affinity IgE receptor, FcεRI, as well as the low-affinity IgG receptor, FcγRIIb. While FcεRI is responsible for IgE-dependent degranulation upon coaggregation with allergens, FcγRIIb has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e4e6ce0a25e077adeb587f8ce600e5a
https://doi.org/10.1159/000358487
https://doi.org/10.1159/000358487
Autor:
Fabian Zellweger, Monique Vogel, Alexander Eggel, Daniel Brigger, Pascal Gasser, Patrick Buschor
Publikováno v:
Allergy. 72(8)
BACKGROUND: Binding of allergen-specific IgE to its high-affinity receptor FceRI on basophils and mast cells is a central event in the development of allergies. Exposure of these cells to allergens induces the release of soluble mediators causing all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9828e285149bdc3bd73161a66b830eda
https://pubmed.ncbi.nlm.nih.gov/27997998
https://pubmed.ncbi.nlm.nih.gov/27997998
Autor:
Alexander Eggel, Beda M. Stadler, Patrick Buschor, Monique Vogel, Michael J. Baumann, Patrick Amstutz
Publikováno v:
Allergy. 66:961-968
Aggregation of the high-affinity IgE receptor (FceRI) with the low-affinity IgG receptor (FcγRIIb) on basophils or mast cells has been shown to inhibit allergen-induced cell degranulation. Molecules cross-linking these two receptors might therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd8353bc4098163f5a9266e528203bae
https://doi.org/10.1111/j.1398-9995.2011.02546.x
https://doi.org/10.1111/j.1398-9995.2011.02546.x
Autor:
Lavinia Morosi, Florian Weiss, Stefan Halbherr, Peter Halbherr, Roberta Affatato, Andreas Konig, Massimo Broggini, Federica Guffanti, Patrick Buschor, Christoph Matthieu
Publikováno v:
Cancer Research. 77:174-174
Background: InnoMedica is a young company with focus on clinical translation of nanomedicine. The company employs its own manufacturing technology that gives rise to a novel liposome platform. The platform allows for specific shaping of nanosurfaces.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::061b36833a4a94a170e9d1e6f74309e3
https://doi.org/10.1158/1538-7445.am2017-174
https://doi.org/10.1158/1538-7445.am2017-174
Publikováno v:
International archives of allergy and immunology. 163(3)
Mast cells and basophils express the high-affinity IgE receptor, FcεRI, as well as the low-affinity IgG receptor, FcγRIIb. While FcεRI is responsible for IgE-dependent degranulation upon coaggregation with allergens, FcγRIIb has been shown to dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f390403af1280f608055c7da06c3a748
https://pubmed.ncbi.nlm.nih.gov/24557487
https://pubmed.ncbi.nlm.nih.gov/24557487
Autor:
Jeoung-Sook Shin, Beomkyu Kim, Gabriel Hobi, Beda M. Stadler, Theodore S. Jardetzky, Monique Vogel, Alexander Eggel, Günther Baravalle, Patrick Buschor, Patrik Forrer, Clemens A. Dahinden
Publikováno v:
The Journal of allergy and clinical immunology
Background The remarkably stable interaction of IgE with its high-affinity receptor FceRI on basophils and mast cells is critical for the induction of allergic hypersensitivity reactions. Because of the exceptionally slow dissociation rate of IgE-Fce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b5d007f0043e77c6ee29f6b9812ec7
https://doi.org/10.1016/j.jaci.2014.02.005
https://doi.org/10.1016/j.jaci.2014.02.005
Publikováno v:
The Journal of Immunology. 192:119.35-119.35
The low affinity receptor for IgE (CD23, FcepsilonRII) is part of the broad regulatory network controlling IgE synthesis. It occurs as membrane and as soluble receptor generated in vivo by specific proteolysis. Targeting membrane CD23 with either IgE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7075b2b43ad3da77a5fca0f6423ce951
https://doi.org/10.4049/jimmunol.192.supp.119.35
https://doi.org/10.4049/jimmunol.192.supp.119.35
Autor:
Silvan Röthlisberger, Marc Fellmann, Patrick Buschor, Fabian Zellweger, Beda Stadler, Monique Vogel
Publikováno v:
The Journal of Immunology. 192:54.18-54.18
Cross-linking two high affinity IgE Receptors (FcεRI) by incubation with an anti-IgE antibody binding to the receptor bound IgE’s leads to a dose dependent bell-shaped activation of basophils. Besides of the high affinity IgE receptor basophils al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0605dd7108541af29805971f2e6b03e5
https://doi.org/10.4049/jimmunol.192.supp.54.18
https://doi.org/10.4049/jimmunol.192.supp.54.18