Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Patrick Bohn"'
Autor:
Wang Liu-Wei, Wiep van der Toorn, Patrick Bohn, Martin Hölzer, Redmond P. Smyth, Max von Kleist
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Direct RNA sequencing (dRNA-seq) on the Oxford Nanopore Technologies (ONT) platforms can produce reads covering up to full-length gene transcripts, while containing decipherable information about RNA base modifications and poly-A
Externí odkaz:
https://doaj.org/article/cd3c7d0cec67474b96de101bc58c8145
Autor:
Patrick Bohn, Irke Waßmann, Lisa Wendt, Anne Leske, Thomas Hoenen, Birke A Tews, Allison Groseth
Publikováno v:
PLoS Pathogens, Vol 19, Iss 1, p e1011049 (2023)
The arenavirus nucleoprotein (NP) plays an important role in the virus' ability to block interferon (IFN) production, and its exonuclease function appears to contribute to this activity. However, efforts to analyze this contribution are complicated b
Externí odkaz:
https://doaj.org/article/e5d7719fe8464b13924a2921d1d19290
Autor:
Judith Lang, Patrick Bohn, Hilal Bhat, Holger Jastrow, Bernd Walkenfort, Feyza Cansiz, Julian Fink, Michael Bauer, Dominik Olszewski, Ana Ramos-Nascimento, Vikas Duhan, Sarah-Kim Friedrich, Katrin Anne Becker, Adalbert Krawczyk, Michael J. Edwards, Andreas Burchert, Magdalena Huber, Justa Friebus-Kardash, Joachim R. Göthert, Cornelia Hardt, Hans Christian Probst, Fabian Schumacher, Karl Köhrer, Burkhard Kleuser, Eduard B. Babiychuk, Beate Sodeik, Jürgen Seibel, Urs F. Greber, Philipp A. Lang, Erich Gulbins, Karl S. Lang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Macrophages are critical in limiting replication of herpes simplex virus type 1 (HSV-1). Here the authors show how acid ceramidase and its enzymatic product sphingosine enable multivesicular bodies to function as an anti-viral mechanism.
Externí odkaz:
https://doaj.org/article/ce87beeac86246829e4b47c4ed971f39
Autor:
Liqing Ye, Uddhav B. Ambi, Marco Olguin-Nava, Anne-Sophie Gribling-Burrer, Shazeb Ahmad, Patrick Bohn, Melanie M. Weber, Redmond P. Smyth
Publikováno v:
Viruses, Vol 13, Iss 9, p 1788 (2021)
To generate infectious viral particles, viruses must specifically select their genomic RNA from milieu that contains a complex mixture of cellular or non-genomic viral RNAs. In this review, we focus on the role of viral encoded RNA structures in geno
Externí odkaz:
https://doaj.org/article/f1f33ddbdbfd4ebb92b21552c10fa2a6
Publikováno v:
Nature Methods.
Genome-wide measurements of RNA structure can be obtained using reagents that react with unpaired bases, leading to adducts that can be identified by mutational profiling on next-generation sequencing machines. One drawback of these experiments is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f597dd74f6747bfdde358a1f9b12aa84
https://doi.org/10.1038/s41592-023-01862-7
https://doi.org/10.1038/s41592-023-01862-7
Direct RNA sequencing (dRNA-seq) on the Oxford Nanopore Technologies (ONT) platforms can produce reads covering up to full-length gene transcripts while containing decipherable information about RNA base modifications and poly-A tail lengths. Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::330789de20dbbb63c08d918f353bf00b
https://doi.org/10.1101/2023.03.29.534691
https://doi.org/10.1101/2023.03.29.534691
Autor:
Patrick Bohn, Irke Waßmann, Lisa Wendt, Anne Leske, Thomas Hoenen, Birke A. Tews, Allison Groseth
Publikováno v:
PLoS pathogens. 19(1)
The arenavirus nucleoprotein (NP) plays an important role in the virus’ ability to block interferon (IFN) production, and its exonuclease function appears to contribute to this activity. However, efforts to analyze this contribution are complicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291f943d056784aa57d9bfd8a4018d77
https://pubmed.ncbi.nlm.nih.gov/36603036
https://pubmed.ncbi.nlm.nih.gov/36603036
Chemical probing experiments interrogate RNA structure by reacting with unpaired residues whose positions are typically read out by mutational profiling on short-read sequencing machines. Such experiments make rapid and genome-wide measurements of RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70b2641e0e4103f97082b0e16c9b5f46
https://doi.org/10.21203/rs.3.rs-1850122/v1
https://doi.org/10.21203/rs.3.rs-1850122/v1
Autor:
Liqing Ye, Anne-Sophie Gribling-Burrer, Patrick Bohn, Anuja Kibe, Charlene Börtlein, Uddhav B. Ambi, Shazeb Ahmad, Marco Olguin-Nava, Maureen Smith, Neva Caliskan, Max von Kleist, Redmond P. Smyth
RNA dimerization is the noncovalent association of two human immunodeficiency virus-1 (HIV-1) genomes. It is a conserved step in the HIV-1 life cycle and assumed to be a prerequisite for binding to the viral structural protein Pr55Gag during genome p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3baf4892f62e5286fd4d2e1b151eed
http://edoc.rki.de/176904/9792
http://edoc.rki.de/176904/9792
Autor:
Liqing Ye, Anne-Sophie Gribling-Burrer, Patrick Bohn, Anuja Kibe, Charlene Börtlein, Uddhav B. Ambi, Shazeb Ahmad, Marco Olguin-Nava, Maureen Smith, Neva Caliskan, Max von Kleist, Redmond P. Smyth
Publikováno v:
Nature Structural & Molecular Biology. 30:403-403
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7eae7ad0382ee58f7ad8a4c03d89254
https://doi.org/10.1038/s41594-023-00946-4
https://doi.org/10.1038/s41594-023-00946-4