Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Patrick Bertolino"'
Autor:
Kieran English, Rain Kwan, Lauren E. Holz, Claire McGuffog, Jelte M. M. Krol, Daryan Kempe, Tsuneyasu Kaisho, William R. Heath, Leszek Lisowski, Maté Biro, Geoffrey W. McCaughan, David G. Bowen, Patrick Bertolino
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract While CD4+ T cells are a prerequisite for CD8+ T cell-mediated protection against intracellular hepatotropic pathogens, the mechanisms facilitating the transfer of CD4-help to intrahepatic CD8+ T cells are unknown. Here, we developed an expe
Externí odkaz:
https://doaj.org/article/6f41999c730741ea852dc4aa086f5180
Autor:
Lauren E. Holz, Julia E. Prier, David Freestone, Thiago M. Steiner, Kieran English, Darryl N. Johnson, Vanessa Mollard, Anton Cozijnsen, Gayle M. Davey, Dale I. Godfrey, Katsuyuki Yui, Laura K. Mackay, Mireille H. Lahoud, Irina Caminschi, Geoffrey I. McFadden, Patrick Bertolino, Daniel Fernandez-Ruiz, William R. Heath
Publikováno v:
Cell Reports, Vol 25, Iss 1, Pp 68-79.e4 (2018)
Summary: Liver tissue-resident memory T (Trm) cells migrate throughout the sinusoids and are capable of protecting against malaria sporozoite challenge. To gain an understanding of liver Trm cell development, we examined various conditions for their
Externí odkaz:
https://doaj.org/article/f5f33bbac9d74ad79fe3d15e26d1c156
Autor:
Kieran English, Sioh Yang Tan, Rain Kwan, Lauren E Holz, Frederic Sierro, Claire McGuffog, Tsuneyasu Kaisho, William R Heath, Kelli PA MacDonald, Geoffrey W McCaughan, David G Bowen, Patrick Bertolino
Publikováno v:
Immunology & Cell Biology. 100:394-408
Publikováno v:
Immunology & Cell Biology. 99:565-569
Autor:
Jinbiao Chen, Yang Zhao, Fan Zhang, Jia Li, Jade A. Boland, Ngan Ching Cheng, Ken Liu, Jessamy C. Tiffen, Patrick Bertolino, David G. Bowen, Andreas Krueger, Leszek Lisowski, Ian E. Alexander, Mathew A. Vadas, Emad El-Omar, Jennifer R. Gamble, Geoffrey W. McCaughan
Publikováno v:
Cellular and Molecular Life Sciences. 79
MiR-181 expression levels increased in hepatocellular carcinoma (HCC) compared to non-cancerous tissues. MiR-181 has been widely reported as a possible driver of tumourigenesis but also acts as a tumour suppressor. In addition, the miR-181 family reg
Autor:
Simone I. Strasser, Ken Liu, Geoffrey W. McCaughan, Avik Majumdar, David G. Bowen, Patrick Bertolino
Publikováno v:
Liver Transplantation
Autor:
Pouya Faridi, Anthony W. Purcell, Eric Taeyoung Son, David G. Bowen, Mario Leong, Patrick Bertolino, Ian E. Alexander, Moumita Paul-Heng, Alexandra F. Sharland, Nicole A. Mifsud, Kieran English, Nadine L. Dudek, Sri H. Ramarathinam, Leszek Lisowski, Asolina Braun
Publikováno v:
Journal of Clinical Investigation. 131
While direct allorecognition underpins both solid organ allograft rejection and tolerance induction, the specific molecular targets of most directly alloreactive CD8+ T cells have not been defined. In this study, we used a combination of genetically
Autor:
Mainthan Palendira, Yingju Xia, Patrick Bertolino, Warwick J. Britton, John Stambas, Carl G. Feng, Manuela Flórido, James A. Triccas, Leon C. W. Lin, Frederic Sierro, H. Muflihah
Publikováno v:
Mucosal Immunology. 11:1743-1752
The lung is the primary site of infection with the major human pathogen, Mycobacterium tuberculosis. Effective vaccines against M. tuberculosis must stimulate memory T cells to provide early protection in the lung. Recently, tissue-resident memory T
TCR Affinity Controls the Dynamics but Not the Functional Specification of the Antimycobacterial CD4
Autor:
Nayan D, Bhattacharyya, Claudio, Counoupas, Lina, Daniel, Guoliang, Zhang, Stuart J, Cook, Taylor A, Cootes, Sebastian A, Stifter, David G, Bowen, James A, Triccas, Patrick, Bertolino, Warwick J, Britton, Carl G, Feng
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 206(12)
The quality of T cell responses depends on the lymphocytes' ability to undergo clonal expansion, acquire effector functions, and traffic to the site of infection. Although TCR signal strength is thought to dominantly shape the T cell response, by usi
Autor:
Leszek Lisowski, Moumita Paul-Heng, Sri H. Ramarathinam, Nicole A. Mifsud, Kieran English, Eric Taeyoung Son, Patrick Bertolino, Ian E. Alexander, Nadine L. Dudek, Asolina Braun, Pouya Faridi, Alexandra F. Sharland, David G. Bowen, Anthony W. Purcell, Mario Leong
While direct allorecognition underpins both solid organ allograft rejection and tolerance induction, the specific molecular targets of most directly-alloreactive CD8+ T cells have not been defined. In this study, we used a combination of genetically-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1203aecab8fabdcb7819246a067f252d
https://doi.org/10.1101/2020.11.09.359968
https://doi.org/10.1101/2020.11.09.359968