Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation

Autor: Troy D. Randall, Kim Kusser, William W. Agace, Serge A. van de Pavert, Gera Goverse, Karen Niederreither, Reina E. Mebius, Mark F. R. Vondenhoff, Mascha Greuter, Brenda J. Olivier, Patrick Beke, Rune Blomhoff, Martin Lipp, Uta E. Höpken, Kasia Sitnik, Wouter J. de Jonge

Publikováno v: Nature immunology, 10(11), 1193-1199. Nature Publishing Group
van de Pavert, S A, Olivier, B J, Goverse, G, Vondenhoff, M F R, Greuter, M J, Beke, P, Kusser, K, Hopken, U E, Lipp, M, Niederreither, K, Blomhoff, R, Sitnik, K, Agace, W W, Randall, TD, Jonge, W & Mebius, R E 2009, ' Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation ', Nature Immunology, vol. 10, no. 11, pp. 1193-1U78 . https://doi.org/10.1038/ni.1789
Nature Immunology, 10(11), 1193-1U78. Nature Publishing Group
Nature immunology

The location of embryonic lymph node development is determined by the initial clustering of lymphoid tissue-inducer (LTi) cells. Here we demonstrate that both the chemokine CXCL13 and the chemokine CCL21 attracted LTi cells at embryonic days 12.5-14.

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https://pure.amc.nl/en/publications/chemokine-cxcl13-is-essential-for-lymph-node-initiation-and-is-induced-by-retinoic-acid-and-neuronal-stimulation(f96217e1-3767-4eef-a28f-476990955c86).html