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pro vyhledávání: '"Patrick Bartholomaeus"'
Autor:
Dmitry Tyrsin, Thomas Hünig, Sergey Chuvpilo, Thomas Bukur, John C. Castle, Ulrich Kalinke, Hartmut Hengel, Valesca Boisguerin, Paula Tabares, Alexey A. Matskevich, Linda Y. Semmler, Patrick Bartholomaeus, Paula S. Römer
Publikováno v:
The Journal of Immunology. 192:2091-2098
Following inconspicuous preclinical testing, the superagonistic anti-CD28 mAb TGN1412 was applied to six study participants who all developed a devastating cytokine storm. We verified that TGN1412 treatment of fresh PBMCs induced only moderate respon