Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Patrick Arriola"'
Autor:
Nicole Koutsodendris, Jessica Blumenfeld, Ayushi Agrawal, Michela Traglia, Brian Grone, Misha Zilberter, Oscar Yip, Antara Rao, Maxine R. Nelson, Yanxia Hao, Reuben Thomas, Seo Yeon Yoon, Patrick Arriola, Yadong Huang
Publikováno v:
Nature aging, vol 3, iss 3
Apolipoprotein E4 (APOE4) is the strongest known genetic risk factor for late-onset Alzheimer’s disease (AD). Conditions of stress or injury induce APOE expression within neurons, but the role of neuronal APOE4 in AD pathogenesis is still unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afe5e2b3e90921ae536bd6d7cbbba0d
https://escholarship.org/uc/item/3mn2s8w7
https://escholarship.org/uc/item/3mn2s8w7
Apolipoprotein E4 (APOE4) genotype and aging are critical risk factors for Alzheimer’s disease (AD). Aged APOE4 knock-in (APOE4-KI) mice have phenotypes reflecting features of AD. We conducted a large-scale single nucleus RNA-sequencing study to id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e10607644e0ca90bd0b18bd6c5a3753d
https://doi.org/10.1101/2022.06.16.496371
https://doi.org/10.1101/2022.06.16.496371