Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Patrick Altermatt"'
Autor:
Naja Nyffenegger, Anna Flace, Ahmet Varol, Patrick Altermatt, Cédric Doucerain, Hanna Sundstrom, Franz Dürrenberger, Vania Manolova
Publikováno v:
HemaSphere, Vol 8, Iss 9, Pp n/a-n/a (2024)
Abstract Hemochromatosis is an inherited iron overload condition caused by mutations that reduce the levels of the iron‐regulatory hormone hepcidin or its binding to ferroportin. The hepcidin–ferroportin axis is pivotal to iron homeostasis, provi
Externí odkaz:
https://doaj.org/article/6275d404ed394da882c80dfa9aa97074
Autor:
Natarajaswamy Kalleda, Anna Flace, Patrick Altermatt, Giada Ingoglia, Cédric Doucerain, Naja Nyffenegger, Franz Dürrenberger, Vania Manolova
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
β-thalassemia is an inherited anemia characterized by ineffective erythropoiesis. Blood transfusions are required for survival in transfusion-dependent β-thalassemia and are also occasionally needed in patients with non-transfusion-dependent β-tha
Externí odkaz:
https://doaj.org/article/686e445672b24fec97d5bcd135b5cf04
Autor:
Elena Farah Lehmann, Márton Liziczai, Katarzyna Drożdżyk, Patrick Altermatt, Cassiano Langini, Vania Manolova, Hanna Sundstrom, Franz Dürrenberger, Raimund Dutzler, Cristina Manatschal
Publikováno v:
eLife, Vol 12 (2023)
A central regulatory mechanism of iron homeostasis in humans involves ferroportin (FPN), the sole cellular iron exporter, and the peptide hormone hepcidin, which inhibits Fe2+ transport and induces internalization and degradation of FPN. Dysregulatio
Externí odkaz:
https://doaj.org/article/4ac4fcae60224999b4e642c1a73380b2
Autor:
Vojtech Dvorak, Tabea Wiedmer, Alvaro Ingles-Prieto, Patrick Altermatt, Helena Batoulis, Felix Bärenz, Eckhard Bender, Daniela Digles, Franz Dürrenberger, Laura H. Heitman, Adriaan P. IJzerman, Douglas B. Kell, Stefanie Kickinger, Daniel Körzö, Philipp Leippe, Thomas Licher, Vania Manolova, Riccardo Rizzetto, Francesca Sassone, Lia Scarabottolo, Avner Schlessinger, Vanessa Schneider, Hubert J. Sijben, Anna-Lena Steck, Hanna Sundström, Sara Tremolada, Maria Wilhelm, Marina Wright Muelas, Diana Zindel, Claire M. Steppan, Giulio Superti-Furga
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The solute carrier (SLC) superfamily represents the biggest family of transporters with important roles in health and disease. Despite being attractive and druggable targets, the majority of SLCs remains understudied. One major hurdle in research on
Externí odkaz:
https://doaj.org/article/57add1b341ee425fb3b53addb4c3b962
Autor:
Márton Liziczai, Elena Farah Lehmann, Katarzyna Drożdżyk, Patrick Altermatt, Cassiano Langini, Vania Manolova, Hanna Sundstrom, Franz Dürrenberger, Raimund Dutzler, Cristina Manatschal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33375ae93130ea3d5ea3085accb79044
https://doi.org/10.7554/elife.83053.sa2
https://doi.org/10.7554/elife.83053.sa2
Autor:
Marcello Polesel, Alvaro Ingles-Prieto, Eirini Christodoulaki, Evandro Ferrada, Cédric Doucerain, Patrick Altermatt, Michelle Knecht, Michael Kuhn, Anna-Lena Steck, Maria Wilhelm, Vania Manolova
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine.
Zinc is the second most prevalent metal element present in living organisms, and control of its concentration is pivotal to physiology. The amount of zinc available to the cell cytoplasm is regulated by the activity of members of the SLC39 family, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f211a097a5e3dd528652e9abbc803d5
https://pubmed.ncbi.nlm.nih.gov/36454509
https://pubmed.ncbi.nlm.nih.gov/36454509
Autor:
Elena F. Lehmann, Márton Liziczai, Katarzyna Drożdżyk, Patrick Altermatt, Vania Manolova, Hanna Sundstrom, Franz Dürrenberger, Raimund Dutzler, Cristina Manatschal
A central regulatory mechanism of iron homeostasis in humans involves ferroportin (FPN), the sole cellular iron exporter, and the peptide hormone hepcidin, which inhibits Fe2+ transport and induces internalization and degradation of FPN. Dysregulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db407b6a8ae6923b2865dde06cef1894
https://doi.org/10.1101/2022.08.29.505642
https://doi.org/10.1101/2022.08.29.505642
Autor:
Alvaro Ingles-Prieto, Douglas B. Kell, Laura H. Heitman, Daniela Digles, Stefanie Kickinger, Patrick Altermatt, Diana Zindel, Adriaan P. IJzerman, Vanessa Schneider, Daniel Körzö, Maria Wilhelm, Tabea Wiedmer, Helena Batoulis, Sara Tremolada, Giulio Superti-Furga, Anna Lena Steck, Marina Wright Muelas, Thomas Licher, Eckhard Bender, Vojtech Dvorak, Hubert J. Sijben, Avner Schlessinger, Franz Dürrenberger, Francesca Sassone, Vania Manolova, Riccardo Rizzetto, Philipp Leippe, Lia Scarabottolo, Felix Bärenz, Hanna Sundström, Claire M. Steppan
Publikováno v:
Frontiers in Pharmacology
Dvorak, V, Wiedmer, T, Ingles-Prieto, A, Altermatt, P, Batoulis, H, Bärenz, F, Bender, E, Digles, D, Dürrenberger, F, Heitman, L H, IJzerman, A P, Kell, D B, Kickinger, S, Körzö, D, Leippe, P, Licher, T, Manolova, V, Rizzetto, R, Sassone, F, Scarabottolo, L, Schlessinger, A, Schneider, V, Sijben, H J, Steck, A L, Sundström, H, Tremolada, S, Wilhelm, M, Wright Muelas, M, Zindel, D, Steppan, C M & Superti-Furga, G 2021, ' An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters ', Frontiers in Pharmacology, vol. 12, 722889 . https://doi.org/10.3389/fphar.2021.722889
Frontiers in Pharmacology, 12, 722889
Frontiers in pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Dvorak, V, Wiedmer, T, Ingles-Prieto, A, Altermatt, P, Batoulis, H, Bärenz, F, Bender, E, Digles, D, Dürrenberger, F, Heitman, L H, IJzerman, A P, Kell, D B, Kickinger, S, Körzö, D, Leippe, P, Licher, T, Manolova, V, Rizzetto, R, Sassone, F, Scarabottolo, L, Schlessinger, A, Schneider, V, Sijben, H J, Steck, A L, Sundström, H, Tremolada, S, Wilhelm, M, Wright Muelas, M, Zindel, D, Steppan, C M & Superti-Furga, G 2021, ' An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters ', Frontiers in Pharmacology, vol. 12, 722889 . https://doi.org/10.3389/fphar.2021.722889
Frontiers in Pharmacology, 12, 722889
Frontiers in pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
The solute carrier (SLC) superfamily represents the biggest family of transporters with important roles in health and disease. Despite being attractive and druggable targets, the majority of SLCs remains understudied. One major hurdle in research on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c538438b273fae113d94d4db91b031c
https://phaidra.univie.ac.at/o:1603733
https://phaidra.univie.ac.at/o:1603733
Autor:
Vania Manolova, Cédric Doucerain, Naja Nyffenegger, Franz Dürrenberger, Patrick Altermatt, Hanna Sundström, Anna Flace, Ahmet Varol
β-Thalassemia is a genetic anemia caused by partial or complete loss of β-globin synthesis, leading to ineffective erythropoiesis and RBCs with a short life span. Currently, there is no efficacious oral medication modifying anemia for patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4b3a46cb567309b695aa494591182a
https://europepmc.org/articles/PMC6934209/
https://europepmc.org/articles/PMC6934209/
Autor:
Patrick Altermatt, Gabriele Kiefer
Publikováno v:
AUS. :20-23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7c8e221818b64e702356812bdcfefe4
https://doi.org/10.4206/aus.2010.n7-05
https://doi.org/10.4206/aus.2010.n7-05