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pro vyhledávání: '"Patrick A. Shramm"'
Publikováno v:
Toxins, Vol 15, Iss 3, p 181 (2023)
Streptavidin-Saporin can be considered a type of ‘secondary’ targeted toxin. The scientific community has taken advantage of this conjugate in clever and fruitful ways using many kinds of biotinylated targeting agents to send saporin into a cell
Externí odkaz:
https://doaj.org/article/4f483359dbc54ac189a831b066f185ec
Publikováno v:
Toxins, Vol 14, Iss 3, p 184 (2022)
Saporin is a ribosome-inactivating protein that can cause inhibition of protein synthesis and causes cell death when delivered inside a cell. Development of commercial Saporin results in a technology termed ‘molecular surgery’, with Saporin as th
Externí odkaz:
https://doaj.org/article/4f74c156601d422085fb5fe7856acb28
Autor:
Leonardo Ancheta, Patrick A. Shramm
Publikováno v:
Cancer Research. 79:2177-2177
Quick and efficient screening of targeting agents that internalize effectively is vital for determining their suitability as potential therapeutics. Some of the most recent successes in the treatment of cancers have been from antibodies to cell surfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1f41e6f4edfc1dac18e6c20daddffc
https://doi.org/10.1158/1538-7445.am2019-2177
https://doi.org/10.1158/1538-7445.am2019-2177