Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Patrick A. Hennessey"'
Autor:
Daria A Gaykalova, Rajita Vatapalli, Yingying Wei, Hua-Ling Tsai, Hao Wang, Chi Zhang, Patrick T Hennessey, Theresa Guo, Marietta Tan, Ryan Li, Julie Ahn, Zubair Khan, William H Westra, Justin A Bishop, David Zaboli, Wayne M Koch, Tanbir Khan, Michael F Ochs, Joseph A Califano
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142148 (2015)
Head and Neck Squamous Cell Carcinoma (HNSCC) is the fifth most common cancer, annually affecting over half a million people worldwide. Presently, there are no accepted biomarkers for clinical detection and surveillance of HNSCC. In this work, a comp
Externí odkaz:
https://doaj.org/article/b58b6929a104455fb52e9a80a48f1a8f
Autor:
Gary J. Latham, Elizabeth Mambo, Daria A. Gaykalova, Will Darden, Justin A. Bishop, Kalyan Buddavarapu, Tiffany Sanford, William H. Westra, Ludmila Danilova, Wenyue Sun, Alex T. Adai, Ryan J. Li, Joseph A. Califano, Jeffery D. Houghton, Michael F. Ochs, Wayne M. Koch, Andrew Hadd, Patrick T. Hennessey, Ashish Choudhary
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 5, p e0233409 (2020)
PLoS ONE, Vol 15, Iss 5, p e0233409 (2020)
Development of head and neck squamous cell carcinoma (HNSCC) is characterized by accumulation of mutations in several oncogenes and tumor suppressor genes. We have formerly described the mutation pattern of HNSCC and described NOTCH signaling pathway
Autor:
Patrick T Hennessey, Tiffany Sanford, Ashish Choudhary, Wojciech W Mydlarz, David Brown, Alex Tamas Adai, Michael F Ochs, Steven A Ahrendt, Elizabeth Mambo, Joseph A Califano
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32307 (2012)
Non small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality world-wide and the majority of cases are diagnosed at late stages of disease. There is currently no cost-effective screening test for NSCLC, and the development of su
Externí odkaz:
https://doaj.org/article/365b8f94c3a94bf493ff47f7c2f588d7
Autor:
Patrick T. Hennessey, Tiffany Sanford, Ashish Choudhary, Wojciech W. Mydlarz, David Brown, Alex Tamas Adai, Michael F. Ochs, Steven A. Ahrendt, Elizabeth Mambo, Joseph A. Califano
Publikováno v:
PLoS ONE, Vol 7, Iss 5 (2012)
Externí odkaz:
https://doaj.org/article/17ca6f6d26da4fe18b9a8228e987d7bc
Autor:
Brian D. Schmit, Carey L. Holleran, Abigail L. Leddy, Gabrielle Brazg, T. George Hornby, Patrick W. Hennessey, Gordhan B. Mahtani
Publikováno v:
Journal of Neurologic Physical Therapy. 42:94-101
Previous data suggest that large amounts of high-intensity stepping training in variable contexts (tasks and environments) may improve locomotor function, aerobic capacity, and treadmill gait kinematics in individuals poststroke. Whether similar trai
Autor:
Patrick T Hennessey, Michael F Ochs, Wojciech W Mydlarz, Wayne Hsueh, Leslie Cope, Wayne Yu, Joseph A Califano
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20584 (2011)
Studies designed to identify novel methylation events related to cancer often employ cancer cell lines in the discovery phase of the experiments and have a relatively low rate of discovery of cancer-related methylation events. An alternative algorith
Externí odkaz:
https://doaj.org/article/d704da5701f14a5b9c0760ca34c31534
Autor:
Patrick T. Hennessey, Joseph A. Califano, Hao Wang, Wojciech K. Mydlarz, Andre Lopez Carvalho
Publikováno v:
Head & Neck. 38:9-14
Background Detection of hypermethylated circulating tumor DNA has the potential to be a minimally invasive, low cost, and reproducible method for cancer detection. Methods We evaluated serum from 100 patients with known head and neck squamous cell ca
Autor:
Daria A. Gaykalova, Christina Michailidi, Christine H. Chung, Elana J. Fertig, Zubair Khan, Julie Ahn, Patrick T. Hennessey, Judith Manola, Marietta Tan, Michael Considine, Kathryn Morton, Chi Zhang, Wayne M. Koch, Joseph A. Califano, Hiroyuki Ozawa, Michael F. Ochs, Rajni Sharma, Justin A. Bishop, William H. Westra, Veronika Zizkova
Publikováno v:
International Journal of Cancer. 137:1879-1889
Using high-throughput analyses and the TRANSFAC database, we characterized TF signatures of head and neck squamous cell carcinoma (HNSCC) subgroups by inferential analysis of target gene expression, correcting for the effects of DNA methylation and c
Autor:
Patrick T, Hennessey, Douglas D, Reh
Publikováno v:
American journal of rhinologyallergy. 27(3)
Benign sinonasal neoplasms are a heterogeneous group of tumors that present with similar symptoms including nasal obstruction, anosmia, rhinorrhea, and epistaxis. The proper workup and accurate diagnosis is essential for these tumors so that the appr
Autor:
Michael F. Ochs, Daria A. Gaykalova, Komal S. Rathi, Joseph A. Califano, Patrick T. Hennessey
Publikováno v:
Drug Development Research. 75:343-347
Gene set analysis provides a method to generate statistical inferences across sets of linked genes, primarily using high-throughput expression data. Common gene sets include biological pathways, operons, and targets of transcriptional regulators. In