Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Patrick A. Dreyfus"'
Autor:
Christina Gedicke‐Hornung, Verena Behrens‐Gawlik, Silke Reischmann, Birgit Geertz, Doreen Stimpel, Florian Weinberger, Saskia Schlossarek, Guillaume Précigout, Ingke Braren, Thomas Eschenhagen, Giulia Mearini, Stéphanie Lorain, Thomas Voit, Patrick A. Dreyfus, Luis Garcia, Lucie Carrier
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 7, Pp 1128-1145 (2013)
Abstract Exon skipping mediated by antisense oligoribonucleotides (AON) is a promising therapeutic approach for genetic disorders, but has not yet been evaluated for cardiac diseases. We investigated the feasibility and efficacy of viral‐mediated A
Externí odkaz:
https://doaj.org/article/2151f46ca23e4c23b5b19581f81c7297
Autor:
PP Tak, Patrick A. Dreyfus, Sébastien Jacques, Gilles Chiocchia, Jelle L. Vosters, Nienke Roescher, John A. Chiorini, Jean Sibilia, Ghada Alsaleh, Xavier Mariette, Jacques-Eric Gottenberg
Publikováno v:
Molecular therapy, 22(4), 821-827. Nature Publishing Group
BAFF (B-cell–activating factor of the tumor necrosis factor family), a pivotal cytokine for B-cell activation, is overexpressed by salivary gland (SG) epithelial cells in primary Sjogren's syndrome (pSS). ΔBAFF, a physiological inhibitor of BAFF,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c57c8c22ee54633c09bd9e1b8a847b5
Autor:
Cyriaque Beley, Adeline Vulin, Thomas Voit, Stéphanie Lorain, Maëva Le Hir, Luis Garcia, Inès Barthélémy, Rachid Benchaouir, Yves Unterfinger, Graziella Griffith, Jean-Laurent Thibaud, Aurélie Goyenvalle, Patrick A. Dreyfus, Pierre G. Carlier, Stéphane Blot
Publikováno v:
Molecular Therapy. 20(11):2120-2133
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder resulting from lesions of the gene encoding dystrophin. These usually consist of large genomic deletions, the extents of which are not correlated with the severity of the phenotype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9c470871ffc1cdfe1331779839db2e
Autor:
François-Jérôme Authier, M Coquet, Ph. Moretto, Patrick Chariot, Patrick A. Dreyfus, Romain K. Gherardi, Patrick Cherin, Jean-François Pellissier, Laurent Bélec
Publikováno v:
Brain. 124:1821-1831
Macrophagic myofasciitis (MMF) is an emerging condition of unknown cause, detected in patients with diffuse arthromyalgias and fatigue, and characterized by muscle infiltration by granular periodic acid-Schiff's reagent-positive macrophages and lymph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2c980717d883c09b0e763937ad0db8
https://doi.org/10.1093/brain/124.9.1821
https://doi.org/10.1093/brain/124.9.1821
Autor:
Muriel Coulpier, Marc Peschanski, Patrick A. Dreyfus, Christelle Monville, Danielle Riche, Elena Cattaneo, Marcienne Tardy, C. Fages, Luciano Conti, Claudio De-Fraja
Publikováno v:
Molecular and Cellular Neuroscience
Molecular and Cellular Neuroscience, Elsevier, 2001, 17 (2), pp.373-384. ⟨10.1006/mcne.2000.0926⟩
Molecular and Cellular Neuroscience, Elsevier, 2001, 17 (2), pp.373-384. ⟨10.1006/mcne.2000.0926⟩
International audience; Ciliary neurotrophic factor (CNTF) acts on immature astrocytes that express its trimeric receptor. In contrast, mature astrocytes do not significantly express the specific CNTFalpha receptor subunit, yet they respond to CNTF a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395a8c12c9a8a04a3b6940a5f437290b
https://doi.org/10.1006/mcne.2000.0926
https://doi.org/10.1006/mcne.2000.0926
Publikováno v:
Glia. 33:277-287
Activated microglia is associated with neurodegenerative processes, but the precise role of this cell population is difficult to identify. Most experimental models employed to examine microglial responses involve acute alterations of neuronal integri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65ca006f8c7aec3493181daa241788c6
https://doi.org/10.1002/1098-1136(20010315)33:4<277::aid-glia1026>3.0.co
https://doi.org/10.1002/1098-1136(20010315)33:4<277::aid-glia1026>3.0.co
Publikováno v:
Journal of Molecular and Cellular Cardiology. 32:1767-1778
Rat neonatal ventricular cardiomyocytes (RNVM) possess G protein-coupled AT(1)receptors for angiotensin II (AngII) that activate multiple intracellular pathways. To elucidate potential signaling mechanisms involved, we focussed on the nuclear transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9ab715a33fd2b78dd834198b003433
https://doi.org/10.1006/jmcc.2000.1211
https://doi.org/10.1006/jmcc.2000.1211
Publikováno v:
Brain Research. 832:84-96
Breakdown of the blood-brain barrier (BBB) and ensuing gliosis are common events following physical trauma to the central nervous system (CNS) or during autoimmune diseases such as experimental allergic encephalomyelitis (EAE). Some studies of EAE in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e803e4421fdf8c6d0b4e58447ae6d72
https://doi.org/10.1016/s0006-8993(99)01479-1
https://doi.org/10.1016/s0006-8993(99)01479-1
Autor:
Micheline Levame, Serge Adnot, Emmanuel Teiger, Chohreh Partovian, Christian Frelin, Bernadette Raffestin, Patrick A. Dreyfus, Saadia Eddahibi
Publikováno v:
Europe PubMed Central
Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen that is upregulated during exposure to hypoxia. In this study, we analyzed heart and lung VEGF mRNA expression and examined pulmonary vascular remodeling as well as myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403f1555feea70357b44d67f1329b9d3
https://doi.org/10.1152/ajpheart.1998.275.6.h1948
https://doi.org/10.1152/ajpheart.1998.275.6.h1948
Autor:
Marie-Pierre Junier, Patrick A. Dreyfus, Camila V. Esguerra, Muriel Coulpier, Marina Tinel, Mathias Bähr, Pascal Legendre
Publikováno v:
1998, 12 (3), pp.168-177. ⟨10.1006/mcne.1998.0708⟩
Motoneuronal degenerative diseases are characterized by their progressivity; once affected, the motoneurons remain in altered states during an intermediate phase of degeneration prior to their final disappearance. Whether this survival period coincid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256a52ea1bce7a3b143a73ef6d82b551
https://doi.org/10.1006/mcne.1998.0708
https://doi.org/10.1006/mcne.1998.0708